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Assessment of gene-by-sex interaction effect on bone mineral density

Liu, Ching-Ti (author)
Estrada, Karol (author)
Yerges-Armstrong, Laura M. (author)
show more...
Amin, Najaf (author)
Evangelou, Evangelos (author)
Li, Guo (author)
Minster, Ryan L. (author)
Carless, Melanie A. (author)
Kammerer, Candace M. (author)
Oei, Ling (author)
Zhou, Yanhua (author)
Alonso, Nerea (author)
Dailiana, Zoe (author)
Eriksson, Joel (author)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Centre for Bone and Arthritis Research,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Garcia-Giralt, Natalia (author)
Giroux, Sylvie (author)
Husted, Lise Bjerre (author)
Khusainova, Rita I. (author)
Koromila, Theodora (author)
Kung, Annie WaiChee (author)
Lewis, Joshua R. (author)
Masi, Laura (author)
Mencej-Bedrac, Simona (author)
Nogues, Xavier (author)
Patel, Millan S. (author)
Prezelj, Janez (author)
Richards, J. Brent (author)
Sham, Pak Chung (author)
Spector, Timothy (author)
Vandenput, Liesbeth, 1974 (author)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Centre for Bone and Arthritis Research,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Xiao, Su-Mei (author)
Zheng, Hou-Feng (author)
Zhu, Kun (author)
Balcells, Susana (author)
Brandi, Maria Luisa (author)
Frost, Morten (author)
Goltzman, David (author)
Gonzalez-Macias, Jesus (author)
Karlsson, Magnus (author)
Lund University,Lunds universitet,Ortopedi - klinisk och molekylär osteoporosforskning,Forskargrupper vid Lunds universitet,Orthopedics - Clinical and Molecular Osteoporosis Research,Lund University Research Groups
Khusnutdinova, Elza K. (author)
Kollia, Panagoula (author)
Langdahl, Bente Lomholt (author)
Ljunggren, Oesten (author)
Lorentzon, Mattias, 1970 (author)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Centre for Bone and Arthritis Research,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Marc, Janja (author)
Mellström, Dan, 1945 (author)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Centre for Bone and Arthritis Research,Institute of Medicine, School of Public Health and Community Medicine
Ohlsson, Claes, 1965 (author)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Centre for Bone and Arthritis Research,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Olmos, Jose M. (author)
Ralston, Stuart H. (author)
Riancho, Jose A. (author)
Rousseau, Francois (author)
Urreizti, Roser (author)
Van Hul, Wim (author)
Zarrabeitia, Maria T. (author)
Castano-Betancourt, Martha (author)
Demissie, Serkalem (author)
Grundberg, Elin (author)
Herrera, Lizbeth (author)
Kwan, Tony (author)
Medina-Gomez, Carolina (author)
Pastinen, Tomi (author)
Sigurdsson, Gunnar (author)
Thorleifsson, Gudmar (author)
VanMeurs, Joyce B. J. (author)
Blangero, John (author)
Hofman, Albert (author)
Liu, Yongmei (author)
Mitchell, Braxton D. (author)
O'Connell, Jeffrey R. (author)
Oostra, Ben A. (author)
Rotter, Jerome I. (author)
Stefansson, Kari (author)
Streeten, Elizabeth A. (author)
Styrkarsdottir, Unnur (author)
Thorsteinsdottir, Unnur (author)
Tylavsky, Frances A. (author)
Uitterlinden, Andre (author)
Cauley, Jane A. (author)
Harris, Tamara B. (author)
Ioannidis, John P. A. (author)
Psaty, Bruce M. (author)
Robbins, John A. (author)
Zillikens, M. Carola (author)
VanDuijn, Cornelia M. (author)
Prince, Richard L. (author)
Karasik, David (author)
Rivadeneira, Fernando (author)
Kiel, Douglas P. (author)
Cupples, L. Adrienne (author)
Hsu, Yi-Hsiang (author)
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 (creator_code:org_t)
2012-09-18
2012
English.
In: Journal of Bone and Mineral Research. - : Wiley. - 1523-4681 .- 0884-0431. ; 27:10, s. 2051-2064
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • Sexual dimorphism in various bone phenotypes, including bone mineral density (BMD), is widely observed; however, the extent to which genes explain these sex differences is unclear. To identify variants with different effects by sex, we examined gene-by-sex autosomal interactions genome-wide, and performed expression quantitative trait loci (eQTL) analysis and bioinformatics network analysis. We conducted an autosomal genome-wide meta-analysis of gene-by-sex interaction on lumbar spine (LS) and femoral neck (FN) BMD in 25,353 individuals from 8 cohorts. In a second stage, we followed up the 12 top single-nucleotide polymorphisms (SNPs; p?

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Ortopedi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Orthopaedics (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Keyword

GENE-BY-SEX INTERACTION
BMD
ASSOCIATION
AGING
gene-by-sex; interaction; BMD; association; aging

Publication and Content Type

art (subject category)
ref (subject category)

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By the author/editor
Liu, Ching-Ti
Estrada, Karol
Yerges-Armstrong ...
Amin, Najaf
Evangelou, Evang ...
Li, Guo
show more...
Minster, Ryan L.
Carless, Melanie ...
Kammerer, Candac ...
Oei, Ling
Zhou, Yanhua
Alonso, Nerea
Dailiana, Zoe
Eriksson, Joel
Garcia-Giralt, N ...
Giroux, Sylvie
Husted, Lise Bje ...
Khusainova, Rita ...
Koromila, Theodo ...
Kung, Annie WaiC ...
Lewis, Joshua R.
Masi, Laura
Mencej-Bedrac, S ...
Nogues, Xavier
Patel, Millan S.
Prezelj, Janez
Richards, J. Bre ...
Sham, Pak Chung
Spector, Timothy
Vandenput, Liesb ...
Xiao, Su-Mei
Zheng, Hou-Feng
Zhu, Kun
Balcells, Susana
Brandi, Maria Lu ...
Frost, Morten
Goltzman, David
Gonzalez-Macias, ...
Karlsson, Magnus
Khusnutdinova, E ...
Kollia, Panagoul ...
Langdahl, Bente ...
Ljunggren, Oeste ...
Lorentzon, Matti ...
Marc, Janja
Mellström, Dan, ...
Ohlsson, Claes, ...
Olmos, Jose M.
Ralston, Stuart ...
Riancho, Jose A.
Rousseau, Franco ...
Urreizti, Roser
Van Hul, Wim
Zarrabeitia, Mar ...
Castano-Betancou ...
Demissie, Serkal ...
Grundberg, Elin
Herrera, Lizbeth
Kwan, Tony
Medina-Gomez, Ca ...
Pastinen, Tomi
Sigurdsson, Gunn ...
Thorleifsson, Gu ...
VanMeurs, Joyce ...
Blangero, John
Hofman, Albert
Liu, Yongmei
Mitchell, Braxto ...
O'Connell, Jeffr ...
Oostra, Ben A.
Rotter, Jerome I ...
Stefansson, Kari
Streeten, Elizab ...
Styrkarsdottir, ...
Thorsteinsdottir ...
Tylavsky, France ...
Uitterlinden, An ...
Cauley, Jane A.
Harris, Tamara B ...
Ioannidis, John ...
Psaty, Bruce M.
Robbins, John A.
Zillikens, M. Ca ...
VanDuijn, Cornel ...
Prince, Richard ...
Karasik, David
Rivadeneira, Fer ...
Kiel, Douglas P.
Cupples, L. Adri ...
Hsu, Yi-Hsiang
show less...
About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Orthopaedics
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Endocrinology an ...
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
Articles in the publication
Journal of Bone ...
By the university
Lund University
University of Gothenburg

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