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New susceptibility locus for coronary artery disease on chromosome 3q22.3

Erdmann, Jeanette (author)
Grosshennig, Anika (author)
Braund, Peter S. (author)
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Koenig, Inke R. (author)
Hengstenberg, Christian (author)
Hall, Alistair S. (author)
Linsel-Nitschke, Patrick (author)
Kathiresan, Sekar (author)
Wright, Ben (author)
Tregouet, David-Alexandre (author)
Cambien, Francois (author)
Bruse, Petra (author)
Aherrahrou, Zouhair (author)
Wagner, Arnika K. (author)
Stark, Klaus (author)
Schwartz, Stephen M. (author)
Salomaa, Veikko (author)
Elosua, Roberto (author)
Melander, Olle (author)
Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups
Voight, Benjamin F. (author)
O'Donnell, Christopher J. (author)
Peltonen, Leena (author)
Siscovick, David S. (author)
Altshuler, David (author)
Merlini, Piera Angelica (author)
Peyvandi, Flora (author)
Bernardinelli, Luisa (author)
Ardissino, Diego (author)
Schillert, Arne (author)
Blankenberg, Stefan (author)
Zeller, Tanja (author)
Wild, Philipp (author)
Schwarz, Daniel F. (author)
Tiret, Laurence (author)
Perret, Claire (author)
Schreiber, Stefan (author)
El Mokhtari, Nour Eddine (author)
Schaefer, Arne (author)
Maerz, Winfried (author)
Renner, Wilfried (author)
Bugert, Peter (author)
Klueter, Harald (author)
Schrezenmeir, Juergen (author)
Rubin, Diana (author)
Ball, Stephen G. (author)
Balmforth, Anthony J. (author)
Wichmann, H-Erich (author)
Meitinger, Thomas (author)
Fischer, Marcus (author)
Meisinger, Christa (author)
Baumert, Jens (author)
Peters, Annette (author)
Ouwehand, Willem H. (author)
Deloukas, Panos (author)
Thompson, John R. (author)
Ziegler, Andreas (author)
Samani, Nilesh J. (author)
Schunkert, Heribert (author)
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 (creator_code:org_t)
2009-02-08
2009
English.
In: Nature Genetics. - : Springer Science and Business Media LLC. - 1546-1718 .- 1061-4036. ; 41:3, s. 280-282
Related links:
http://dx.doi.org/10...
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https://europepmc.or...
https://lup.lub.lu.s...
https://doi.org/10.1...
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  • Journal article (peer-reviewed)
Abstract Subject headings
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  • We present a three-stage analysis of genome-wide SNP data in 1,222 German individuals with myocardial infarction and 1,298 controls, in silico replication in three additional genome-wide datasets of coronary artery disease (CAD) and subsequent replication in similar to 25,000 subjects. We identified one new CAD risk locus on 3q22.3 in MRAS (P = 7.44 x 10(-13); OR = 1.15, 95% CI = 1.11-1.19), and suggestive association with a locus on 12q24.31 near HNF1A-C12orf43 (P = 4.81 x 10(-7); OR = 1.08, 95% CI = 1.05-1.11).

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Publication and Content Type

art (subject category)
ref (subject category)

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