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Sökning: onr:"swepub:oai:gup.ub.gu.se/307558" > Cumulative incidenc...

Cumulative incidence of ureteroenteric strictures after radical cystectomy in a population-based Swedish cohort

Magnusson, J. (författare)
Department of Urology, Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Urol, Bruna Straket 11B, S-41345 Gothenburg, Sweden.
Hagberg, Oskar (författare)
Lund University,Lunds universitet,Urologi - blåscancer, Malmö,Forskargrupper vid Lunds universitet,Urology - urothelial cancer, Malmö,Lund University Research Groups
Abdul-Sattar Aljabery, Firas (författare)
Linköping University,Linköpings universitet,Medicinska fakulteten,Avdelningen för kirurgi, ortopedi och onkologi,Region Östergötland, Urologiska kliniken i Östergötland
visa fler...
Hosseini, A. (författare)
Department of Molecular Medicine and Surgery, Karolinska Institutet and Department of Pelvic Surgery, Karolinska University Hospital, Stockholm, Sweden,Karolinska Univ Hosp, Karolinska Inst, Dept Mol Med & Surg, Stockholm, Sweden.;Karolinska Univ Hosp, Dept Pelv Surg, Stockholm, Sweden.
Jahnson, Staffan (författare)
Linköping University,Linköpings universitet,Avdelningen för Kirurgi, Ortopedi och Onkologi,Medicinska fakulteten,Region Östergötland, Urologiska kliniken i Östergötland
Jerlström, Tomas, 1969- (författare)
Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Urology, School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Örebro Univ, Fac Med & Hlth, Sch Med Sci, Dept Urol, Örebro, Sweden.
Sherif, Amir (författare)
Umeå University,Umeå universitet,Urologi och andrologi,Umeå Univ, Dept Surg & Perioperat Sci Urol & Androl, Umeå, Sweden.
Soderkvist, K. (författare)
Umeå University
Ströck, Viveka (författare)
Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för urologi,Institute of Clinical Sciences, Department of Urology,Department of Urology, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Urology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Urol, Bruna Straket 11B, S-41345 Gothenburg, Sweden.;Univ Gothenburg, Sahlgrenska Acad, Inst Clin Sci, Dept Urol, Gothenburg, Sweden.
Ullen, A. (författare)
Karolinska Institutet
Häggström, Christel (författare)
Uppsala University,Umeå University,Uppsala universitet,Umeå universitet,Näringsforskning,Department of Surgical Sciences, Uppsala University, Uppsala, Sweden;,Endokrinkirurgi,Uppsala Univ, Dept Surg Sci, Uppsala, Sweden.;Umeå Univ, Northern Register Ctr, Dept Publ Hlth & Clin Med, Umeå, Sweden.
Holmberg, L. (författare)
Uppsala University,King's College London
Kjölhede, Henrik, 1981 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för urologi,Institute of Clinical Sciences, Department of Urology,Department of Urology, Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Urology, Institute of Clinical Science, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Urol, Bruna Straket 11B, S-41345 Gothenburg, Sweden.;Univ Gothenburg, Sahlgrenska Acad, Inst Clin Sci, Dept Urol, Gothenburg, Sweden.
Söderström, Karin (författare)
Umeå universitet,Onkologi
visa färre...
Department of Urology, Sahlgrenska University Hospital, Gothenburg, Sweden Sahlgrens Univ Hosp, Dept Urol, Bruna Straket 11B, S-41345 Gothenburg, Sweden (creator_code:org_t)
2021-07-27
2021
Engelska.
Ingår i: Scandinavian Journal of Urology. - : Medical Journals Sweden AB. - 2168-1805 .- 2168-1813. ; 55:5, s. 361-365
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Objective The incidence of benign ureteroenteric strictures following radical cystectomy (RC) for urinary bladder cancer (UBC) is investigated mainly in single-centre studies from high-volume centres. The aim of this study was to evaluate the cumulative incidence of strictures and risk factors in a population-based cohort. Patients and methods Data was collected from Bladder Cancer Data Base Sweden (BladderBaSe). The primary endpoint was stricture with intervention. Secondary endpoint included hydronephrosis both with/without intervention. Results In total, 5,816 patients were registered as having had RC due to UBC between 1997 and 2014. After a median follow-up of 23.5 months (IQR = 9.0-63.1 months; range = 0.0-214.0 months), we found that 515 (8.9%) patients underwent intervention for stricture. Seven hundred and sixty-one (13.1%) patients were diagnosed with hydronephrosis without intervention. The cumulative incidence of strictures with intervention was 19.7% (95% CI = 16.7-23.1%) during the 17 years of follow-up. In the first year, the cumulative incidence of strictures was 5.6% (95% CI = 5.0-6.2%), and in the first 2 years 8.4% (95% CI = 7.6-9.3%). For the secondary endpoint, the cumulative incidence was 30.4% (95% CI = 26.7-33.1%) after 17 years. Only the year of RC was associated with stricture incidence in Cox regression analysis, whereas hospital cystectomy volume, patient age and patient sex were not. Conclusion Ureteroenteric strictures requiring intervention may be more common than previously reported, affecting nearly one fifth of patients who have undergone RC for UBC. The annual incidence was highest in the first 2 years after surgery but the cumulative incidence increased continuously during 17 years of follow-up.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Nyckelord

bladder cancer
ureteric stricture
population-based
radical
cystectomy
complications
urinary-diversion
Urology & Nephrology
Bladder cancer
radical cystectomy

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