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Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study

Deschasaux, M. (författare)
Sorbonne Paris Nord University
Huybrechts, I. (författare)
International Agency for Research on Cancer, World Health Organization
Murphy, N. (författare)
International Agency for Research on Cancer, World Health Organization
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Julia, C. (författare)
Sorbonne Paris Nord University
Hercberg, S. (författare)
Sorbonne Paris Nord University
Srour, B. (författare)
Sorbonne Paris Nord University
Kesse-Guyot, E. (författare)
Sorbonne Paris Nord University
Latino-Martel, P. (författare)
Sorbonne Paris Nord University
Biessy, C. (författare)
International Agency for Research on Cancer, World Health Organization
Casagrande, C. (författare)
International Agency for Research on Cancer, World Health Organization,Aarhus University
Jenab, M. (författare)
International Agency for Research on Cancer, World Health Organization
Ward, H. (författare)
Imperial College London
Weiderpass, E. (författare)
Karolinska Institutet,Karolinska Institute,University of Helsinki,Folkhälsan Research Center,Cancer Registry of Norway, Institute of Population-Based Cancer Research,UiT The Arctic University of Norway, Tromsø
Dahm, C. C. (författare)
Overvad, K. (författare)
Aarhus University
Kyro, C. (författare)
Danish Cancer Society
Olsen, A. (författare)
Danish Cancer Society
Affret, A. (författare)
University of Paris-Saclay,Institut Gustave Roussy
Boutron-Ruault, M. C. (författare)
Institut Gustave Roussy,University of Paris-Saclay
Mahamat-Saleh, Y. (författare)
Institut Gustave Roussy,University of Paris-Saclay
Kaaks, R. (författare)
German Cancer Research Centre
Kuhn, T. (författare)
German Cancer Research Centre,University of Ioannina,Imperial College London
Boeing, H. (författare)
German Institute of Human Nutrition
Schwingshackl, L. (författare)
German Institute of Human Nutrition
Bamia, C. (författare)
National and Kapodistrian University of Athens,Hellenic Health Foundation, Athens
Peppa, E. (författare)
Hellenic Health Foundation, Athens
Trichopoulou, A. (författare)
Hellenic Health Foundation, Athens,National and Kapodistrian University of Athens
Masala, G. (författare)
Cancer Research and Prevention Institute (ISPO)
Krogh, V. (författare)
Istituto Nazionale dei Tumori
Panico, S. (författare)
University of Naples Federico II
Tumino, R. (författare)
Civic and M.P Arezzo Hospital
Sacerdote, C. (författare)
Citta' della Salute e della Scienza Hospital-University of Turin
Buen-de-Mesquita, B. (författare)
National Institute for Public Health and the Environment (RIVM),University Medical Center Utrecht,Imperial College London,University of Malaya
Peeters, P. H. (författare)
University Medical Center Utrecht
Hjartaker, A. (författare)
University of Oslo
Rylander, C. (författare)
UiT The Arctic University of Norway, Tromsø
Skeie, G. (författare)
UiT The Arctic University of Norway, Tromsø
Quiros, J. R. (författare)
Public Health Directorate
Jakszyn, P. (författare)
Catalan Institute of Oncology,Ramon Llull University
Salamanca-Fernandez, E. (författare)
CIBER Epidemiology and Public Health (CIBERESP),University of Granada
Huerta, J. M. (författare)
CIBER Epidemiology and Public Health (CIBERESP),Murcia Regional Health Council
Ardanaz, Eva (författare)
CIBER Epidemiology and Public Health (CIBERESP),Health Research Institute of Navarra (IDISNA)
Amiano, P. (författare)
CIBER Epidemiology and Public Health (CIBERESP),Basque Government
Ericson, Ulrika (författare)
Lund University,Lunds universitet,Diabetes - kardiovaskulär sjukdom,Forskargrupper vid Lunds universitet,Diabetes - Cardiovascular Disease,Lund University Research Groups
Sonestedt, Emily (författare)
Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups
Huseinovic, Ena (författare)
University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Johansson, Ingegerd (författare)
Umeå University,Umeå universitet,Institutionen för odontologi
Khaw, K. T. (författare)
University of Cambridge,Addenbrooke's Hospital
Wareham, N. (författare)
University of Cambridge
Bradbury, K. E. (författare)
University of Oxford
Perez-Cornago, A. (författare)
University of Oxford
Tsilidis, K. K. (författare)
Ferrari, P. (författare)
International Agency for Research on Cancer, World Health Organization
Riboli, E. (författare)
Imperial College London
Gunter, M. J. (författare)
Touvier, M. (författare)
Sorbonne Paris Nord University
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 (creator_code:org_t)
2018-09-18
2018
Engelska.
Ingår i: Plos Medicine. - : Public Library of Science (PLoS). - 1549-1676 .- 1549-1277. ; 15:9
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background Helping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling system to reflect the nutritional quality of food products. The Nutri-Score, a five-colour nutrition label, is derived from the Nutrient Profiling System of the British Food Standards Agency (modified version) (FSAm-NPS). How the consumption of foods with high/low FSAm-NPS relates to cancer risk has been studied in national/regional cohorts but has not been characterized in diverse European populations. This prospective analysis included 471,495 adults from the European Prospective Investigation into Cancer and Nutrition (EPIC, 1992-2014, median follow-up: 15.3 y), among whom there were 49,794 incident cancer cases (main locations: breast, n = 12,063; prostate, n = 6,745; colon-rectum, n = 5,806). Usual food intakes were assessed with standardized country-specific diet assessment methods. The FSAm-NPS was calculated for each food/beverage using their 100-g content in energy, sugar, saturated fatty acid, sodium, fibres, proteins, and fruits/vegetables/legumes/nuts. The FSAm-NPS scores of all food items usually consumed by a participant were averaged to obtain the individual FSAm-NPS Dietary Index (DI) scores. Multi-adjusted Cox proportional hazards models were computed. A higher FSAm-NPS DI score, reflecting a lower nutritional quality of the food consumed, was associated with a higher risk of total cancer (HRQ5 versus (Q1) = 1.07; 95% CI 1.03-1.10, P-trend < 0.001). Absolute cancer rates in those with high and low (quintiles 5 and 1) FSAm-NPS DI scores were 81.4 and 69.5 cases/10,000 person-years, respectively. Higher FSAm-NPS DI scores were specifically associated with higher risks of cancers of the colon-rectum, upper aerodigestive tract and stomach, lung for men, and liver and postmenopausal breast for women (all P < 0.05). The main study limitation is that it was based on an observational cohort using self-reported dietary data obtained through a single baseline food frequency questionnaire; thus, exposure misclassification and residual confounding cannot be ruled out. In this large multinational European cohort, the consumption of food products with a higher FSAm-NPS score (lower nutritional quality) was associated with a higher risk of cancer. This supports the relevance of the FSAm-NPS as underlying nutrient profiling system for front-of-pack nutrition labels, as well as for other public health nutritional measures.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Näringslära (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

Nyckelord

cardiovascular-disease risk
front-of-package
dietary index
prospective association
su.vi.max cohort
french adults
validation
database
project
france
General & Internal Medicine

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