Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models

Allesøe, Rosa Lundbye (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark; Copenhagen Research Centre for Mental Health, Mental Health Centre Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark

Lundgaard, Agnete Troen (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Hernández Medina, Ricardo (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Aguayo-Orozco, Alejandro (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Johansen, Joachim (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Nissen, Jakob Nybo (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Brorsson, Caroline (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Mazzoni, Gianluca (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Niu, Lili (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Biel, Jorge Hernansanz (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Brasas, Valentas (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Webel, Henry (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Benros, Michael Eriksen (författare)

Copenhagen Research Centre for Mental Health, Mental Health Centre Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark; Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Pedersen, Anders Gorm (författare)

Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Chmura, Piotr Jaroslaw (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Jacobsen, Ulrik Plesner (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Mari, Andrea (författare)

C.N.R. Institute of Neuroscience, Padova, Italy

Koivula, Robert (författare)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK

Mahajan, Anubha (författare)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK

Vinuela, Ana (författare)

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK

Tajes, Juan Fernandez (författare)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK

Sharma, Sapna (författare)

Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Bavaria, Germany, Bavaria; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Bavaria, Germany, Bavaria; Chair of Food Chemistry and Molecular and Sensory Science, Technical University of Munich, Freising, Germany

Haid, Mark (författare)

Metabolomics and Proteomics Core, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health, Neuherberg, Germany

Hong, Mun-Gwan (författare)

KTH,Science for Life Laboratory, SciLifeLab,Proteinvetenskap

Musholt, Petra B. (författare)

Research and Development Global Development, Translational Medicine and Clinical Pharmacology, Sanofi-Aventis Deutschland, Frankfurt, Germany

De Masi, Federico (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Vogt, Josef (författare)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Pedersen, Helle Krogh (författare)

Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Gudmundsdottir, Valborg (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Jones, Angus (författare)

University of Exeter Medical School, Exeter, UK

Kennedy, Gwen (författare)

The Immunoassay Biomarker Core Laboratory, School of Medicine, University of Dundee, Dundee, UK

Bell, Jimmy (författare)

Research Centre for Optimal Health, Department of Life Sciences, University of Westminster, London, UK

Thomas, E. Louise (författare)

Research Centre for Optimal Health, Department of Life Sciences, University of Westminster, London, UK

Frost, Gary (författare)

Section for Nutrition Research, Faculty of Medicine, Imperial College London, London, UK

Thomsen, Henrik (författare)

Department of Radiology, Copenhagen University Hospital Herlev-Gentofte, Herlev, Denmark

Hansen, Elizaveta (författare)

Department of Radiology, Copenhagen University Hospital Herlev-Gentofte, Herlev, Denmark

Hansen, Tue Haldor (författare)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Vestergaard, Henrik (författare)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Ridderstråle, M. (författare)

Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups

Blom, Marieke T. (författare)

Department of General Practice, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands

‘t Hart, Leen M. (författare)

Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands; Department of Biomedical Data Science, Section Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands

Pattou, Francois (författare)

Inserm, Univ Lille, CHU Lille, Lille Pasteur Institute, EGID, Lille, France

Raverdy, Violeta (författare)

Inserm, Univ Lille, CHU Lille, Lille Pasteur Institute, EGID, Lille, France

Brage, Soren (författare)

MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK

Kokkola, Tarja (författare)

Department of Medicine, University of Eastern Finland, Kuopio, Finland

Heggie, Alison (författare)

Institute of Cellular Medicine, Newcastle University, Newcastle, UK

McEvoy, Donna (författare)

Diabetes Research Network, Royal Victoria Infirmary, Newcastle, UK

Klintenberg, M. (författare)

Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups

Kaye, Jane (författare)

Centre for Health, Law and Emerging Technologies (HeLEX), Faculty of Law, University of Oxford, Oxford, UK

Hattersley, Andrew (författare)

University of Exeter Medical School, Exeter, UK

McDonald, Timothy (författare)

University of Exeter Medical School, Exeter, UK

Ridderstråle, Martin (författare)

Lund University Diabetes Centre, Department of Clinical Sciences, Lund University, Malmö, Sweden

Walker, Mark (författare)

Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle, UK

Forgie, Ian (författare)

Division of Population Health & Genomics, School of Medicine, University of Dundee, Dundee, UK

Giordano, G.N. (författare)

Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups

Pavo, Imre (författare)

Eli Lilly Regional Operations, Vienna, Austria

Ruetten, Hartmut (författare)

Research and Development Global Development, Translational Medicine and Clinical Pharmacology, Sanofi-Aventis Deutschland, Frankfurt, Germany

Pedersen, Oluf (författare)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Hansen, Torben (författare)

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Dermitzakis, Emmanouil (författare)

Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland

Franks, P.W. (författare)

Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups

Schwenk, Jochen M. (författare)

KTH,Science for Life Laboratory, SciLifeLab,Affinitets-proteomik

Adamski, Jerzy (författare)

Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

McCarthy, Mark I. (författare)

Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK; Genentech, South San Francisco, CA, USA

Pearson, Ewan (författare)

Division of Population Health & Genomics, School of Medicine, University of Dundee, Dundee, UK

Banasik, Karina (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Rasmussen, Simon (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Brunak, Søren (författare)

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Froguel, Philippe (författare)

Inserm, Univ Lille, CHU Lille, Lille Pasteur Institute, EGID, Lille, France; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK

Thomas, Cecilia Engel (författare)

KTH,Affinitets-proteomik,Science for Life Laboratory, SciLifeLab,Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Häussler, Ragna S. (författare)

KTH,Affinitets-proteomik,Science for Life Laboratory, SciLifeLab

Beulens, Joline (författare)

Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands

Rutters, Femke (författare)

Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands

Nijpels, Giel (författare)

Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands

van Oort, Sabine (författare)

Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands

Groeneveld, Lenka (författare)

Department of Epidemiology and Data Science, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands

Elders, Petra (författare)

Department of General Practice, Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands

Giorgino, Toni (författare)

Biophysics Institute (IBF-CNR), National Research Council of Italy, Milan, Italy; Department of Biosciences, University of Milan, Milan, Italy

Rodriquez, Marianne (författare)

Biotech & Biomarkers Research Department, Institut de Recherches Internationales Servier, Croissy sur Seine, France

Nice, Rachel (författare)

Blood Sciences, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK

Perry, Mandy (författare)

Blood Sciences, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK

Bianzano, Susanna (författare)

Boehringer Ingelheim International, Therapeutic Area CardioMetabolism and Respiratory Medicine, Ingelheim am Rhein, Germany

Graefe-Mody, Ulrike (författare)

Boehringer Ingelheim International, Therapeutic Area CNS, Retinopathies and Emerging Areas, Ingelheim am Rhein, Germany

Hennige, Anita (författare)

Boehringer Ingelheim International, Medicine Cardiometabolism and Respiratory, Biberach an der Riss, Germany

Grempler, Rolf (författare)

Boehringer Ingelheim International, Translational Medicine & Clinical Pharmacology, Biberach an der Riss, Germany

Baum, Patrick (författare)

Boehringer Ingelheim International, Translational Medicine & Clinical Pharmacology, Biberach an der Riss, Germany

Stærfeldt, Hans Henrik (författare)

Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

Shah, Nisha (författare)

Centre for Health, Law and Emerging Technologies (HeLEX), Faculty of Law, University of Oxford, Oxford, UK

Teare, Harriet (författare)

Centre for Health, Law and Emerging Technologies (HeLEX), Faculty of Law, University of Oxford, Oxford, UK

Ehrhardt, Beate (författare)

Centre for Mathematics and Algorithms for Data, University of Bath, Bath, UK

Tillner, Joachim (författare)

Clinical Operations, Sanofi-Aventis Deutschland, Frankfurt, Germany

Dings, Christiane (författare)

Clinical Pharmacy, Saarland University, Saarbrücken, Germany

Lehr, Thorsten (författare)

Clinical Pharmacy, Saarland University, Saarbrücken, Germany

Scherer, Nina (författare)

Clinical Pharmacy, Saarland University, Saarbrücken, Germany

Sihinevich, Iryna (författare)

Clinical Pharmacy, Saarland University, Saarbrücken, Germany

Cabrelli, Louise (författare)

Clinical Research Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland, UK, Scotland

Loftus, Heather (författare)

Clinical Research Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee, Scotland, UK, Scotland

Bizzotto, Roberto (författare)

C.N.R. Institute of Neuroscience, Padova, Italy

Tura, Andrea (författare)

C.N.R. Institute of Neuroscience, Padova, Italy

Dekkers, Koen (författare)

Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands

Groop, L. (författare)

Lund University,Lunds universitet,Genomik, diabetes och endokrinologi,Forskargrupper vid Lunds universitet,Genomics, Diabetes and Endocrinology,Lund University Research Groups

Pasdar, N.A. (författare)

Fitipaldi, H. (författare)

Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups

Kurbasic, A. (författare)

Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups

Mutie, P. (författare)

Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups

Pomares-Millan, H. (författare)

Lund University,Lunds universitet,Genetisk och molekylär epidemiologi,Forskargrupper vid Lunds universitet,Genetic and Molecular Epidemiology,Lund University Research Groups

Abdalla, M. (författare)

University of Oxford

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 (creator_code:org_t)

2023-01-02

2023

Engelska.

Ingår i: Nature Biotechnology. - : Springer Nature. - 1087-0156 .- 1546-1696. ; 41:3, s. 399-408

Relaterad länk:

https://doi.org/10.1...

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