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Sökning: onr:"swepub:oai:DiVA.org:umu-212087" > Drinking alcohol in...

Drinking alcohol in moderation is associated with lower rate of all-cause mortality in individuals with higher rather than lower educational level : findings from the MORGAM project

Di Castelnuovo, Augusto (författare)
Mediterranea Cardiocentro, Naples, Italy
Bonaccio, Marialaura (författare)
Department of Epidemiology and Prevention, IRCCS NEUROMED, IS, Pozzilli, Italy
Costanzo, Simona (författare)
Department of Epidemiology and Prevention, IRCCS NEUROMED, IS, Pozzilli, Italy
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McElduff, Patrick (författare)
Hunter Medical Research Institute, University of Newcastle, Newcastle, Australia
Linneberg, Allen (författare)
Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Salomaa, Veikko (författare)
Finnish Institute for Health and Welfare, Helsinki, Finland
Männistö, Satu (författare)
Finnish Institute for Health and Welfare, Helsinki, Finland
Ferrières, Jean (författare)
Department of Cardiology and INSERM UMR 1295, Toulouse University Hospital, Toulouse, France
Dallongeville, Jean (författare)
Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1167 - RID-AGE, Lille, France
Thorand, Barbara (författare)
Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany
Brenner, Hermann (författare)
Division of Clinical Epidemiology and Aging Research and Division of Preventive Oncology, German Cancer Research Center, Heidelberg, Germany
Ferrario, Marco (författare)
Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Varese, Italy
Veronesi, Giovanni (författare)
Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Varese, Italy
Tamosiunas, Abdonas (författare)
Lithuanian University of Health Sciences, Kaunas, Lithuania
Grimsgaard, Sameline (författare)
Department of Community Medicine, Faculty of Health Sciences, UiT the Arctic University of Norway, Tromsø, Norway
Drygas, Wojciech (författare)
Department of Epidemiology CVD Prevention and Health Promotion, National Institute of Cardiology, Warsaw, Poland; Calisia University, Kalisz, Poland
Malyutina, Sofia (författare)
The Institute of Internal and Preventive Medicine -Branch of the “FRC Institute of Cytology and Genetics SB RAS”, Novosibirsk, Russian Federation
Söderberg, Stefan (författare)
Umeå universitet,Institutionen för folkhälsa och klinisk medicin
Nordendahl, Maria (författare)
Umeå universitet,Institutionen för folkhälsa och klinisk medicin
Kee, Frank (författare)
Centre for Public Health, Queens University of Belfast, Belfast, United Kingdom
Grassi, Guido (författare)
Clinica Medica, Università Milano-Bicocca, Milan, Italy
Dabboura, Salim (författare)
Clinic of General and Interventional Cardiology, University Heart & Vascular Center Hamburg, Germany, and German Center for Cardiovascular Research, partner site Hamburg/Lübeck/Kiel, Hamburg, Germany
Borchini, Rossana (författare)
Occupational and Preventive Medicine, ASST Lariana, Como, Italy
Westermann, Dirk (författare)
Department for Cardiology and Angiology, Medical Faculty of Medicine, University Heart Center Freiburg-Bad Krozingen, University of Freiburg, Freiburg, Germany
Schrage, Benedikt (författare)
Clinic of General and Interventional Cardiology, University Heart & Vascular Center Hamburg, Germany, and German Center for Cardiovascular Research, partner site Hamburg/Lübeck/Kiel, Hamburg, Germany
Zeller, Tanja (författare)
Clinic of General and Interventional Cardiology, University Heart & Vascular Center Hamburg, Germany, and German Center for Cardiovascular Research, partner site Hamburg/Lübeck/Kiel, Hamburg, Germany
Kuulasmaa, Kari (författare)
Finnish Institute for Health and Welfare, Helsinki, Finland
Blankenberg, Stefan (författare)
Clinic of General and Interventional Cardiology, University Heart & Vascular Center Hamburg, Germany, and German Center for Cardiovascular Research, partner site Hamburg/Lübeck/Kiel, Hamburg, Germany
Donati, Maria Benedetta (författare)
Department of Epidemiology and Prevention, IRCCS NEUROMED, IS, Pozzilli, Italy
Iacoviello, Licia (författare)
Department of Epidemiology and Prevention, IRCCS NEUROMED, IS, Pozzilli, Italy; Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Varese, Italy
de Gaetano, Giovanni (författare)
Department of Epidemiology and Prevention, IRCCS NEUROMED, IS, Pozzilli, Italy
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 (creator_code:org_t)
Springer Nature, 2023
2023
Engelska.
Ingår i: European Journal of Epidemiology. - : Springer Nature. - 0393-2990 .- 1573-7284. ; 38:8, s. 869-881
Relaterad länk:
https://urn.kb.se/re...
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https://doi.org/10.1...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • The association between socioeconomic status (SES) and alcohol-related diseases has been widely explored. Less is known, however, on whether the association of moderate drinking with all-cause mortality is modified by educational level (EL). Using harmonized data from 16 cohorts in the MORGAM Project (N = 142,066) the association of pattern of alcohol intake with hazard of all-cause mortality across EL (lower = primary-school; middle = secondary-school; higher = university/college degree) was assessed using multivariable Cox-regression and spline curves. A total of 16,695 deaths occurred in 11.8 years (median). In comparison with life-long abstainers, participants drinking 0.1–10 g/d of ethanol had 13% (HR = 0.87; 95%CI: 0.74–1.02), 11% (HR = 0.89; 0.84–0.95) and 5% (HR = 0.95; 0.89–1.02) lower rate of death in higher, middle and lower EL, respectively. Conversely, drinkers > 20 g/d had 1% (HR = 1.01; 0.82–1.25), 10% (HR = 1.10; 1.02–1.19) and 17% (HR = 1.17; 1.09–1.26) higher rate of death. The association of alcohol consumption with all-cause mortality was nonlinear, with a different J-shape by EL levels. It was consistent across both sexes and in various approaches of measuring alcohol consumption, including combining quantity and frequency and it was more evident when the beverage of preference was wine. We observed that drinking in moderation (≤ 10 g/d) is associated with lower mortality rate more evidently in individuals with higher EL than in people with lower EL, while heavy drinking is associated with higher mortality rate more evidently in individuals with lower EL than in people with higher EL, suggesting that advice on reducing alcohol intake should especially target individuals of low EL.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

Nyckelord

Alcohol
All-cause mortality
Educational levels
Social status

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