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Free beta- human ch...
Free beta- human chorionic gonadotropin, total human chorionic gonadotropin and maternal risk of breast cancer
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Toriola, Adetunji T. (författare)
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- Tolockiene, Egle (författare)
- Umeå universitet,Patologi
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- Schock, Helena (författare)
- Umeå universitet,Patologi
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Surcel, Helja-Marja (författare)
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Zeleniuch-Jacquotte, Anne (författare)
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- Wadell, Göran (författare)
- Umeå universitet,Virologi
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Toniolo, Paolo (författare)
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- Lundin, Eva (författare)
- Umeå universitet,Patologi
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- Grankvist, Kjell (författare)
- Umeå universitet,Klinisk kemi
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- Lukanova, Annekatrin (författare)
- Umeå universitet,Patologi
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(creator_code:org_t)
- 2014
- 2014
- Engelska.
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Ingår i: Future Oncology. - 1479-6694 .- 1744-8301. ; 10:3, s. 377-384
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.2...
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Abstract
Ämnesord
Stäng
- Background: We investigated whether the free -human chorionic gonadotropin (free -hCG) would provide additional information to that provided by total hCG alone and thus be useful in future epidemiological studies relating hCG to maternal breast cancer risk. Materials & methods: Cases (n = 159) and controls (n = 286) were a subset of our previous study within the Northern Sweden Maternity Cohort on total hCG during primiparous pregnancy and breast cancer risk. Results: The associations between total hCG (hazard ratio: 0.79; 95% CI: 0.49-1.27), free -hCG (hazard ratio: 0.85; 95% CI: 0.33-2.18) and maternal risk of breast cancer were very similar in all analyses and mutual adjustment for either one had minor effects on the risk estimates. Conclusion: In the absence of a reliable assay on intact hCG, total hCG alone can be used in epidemiological studies investigating hCG and breast cancer risk, as free -hCG does not appear to provide any additional information.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- breast cancer
- free -human chorionic gonadotropin
- human chorionic gonadotropin
- nested case-control study
- pregnancy
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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