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Sökning: onr:"swepub:oai:lup.lub.lu.se:ebf50aab-c58d-40d4-aaa9-56503a048e69" > The association bet...

The association between adult attained height and sitting height with mortality in the European prospective investigation into cancer and nutrition (EPIC)

Sawada, Norie (författare)
Imperial College London,National Cancer Center Tokyo
Wark, Petra A. (författare)
Imperial College London
Merritt, Melissa A (författare)
Imperial College London
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Tsugane, Shoichiro (författare)
National Cancer Center Tokyo
Ward, Heather A. (författare)
Imperial College London
Rinaldi, Sabina (författare)
International Agency for Research on Cancer, World Health Organization
Weiderpass, Elisabete (författare)
Karolinska Institutet,UiT The Arctic University of Norway, Tromsø,Cancer Registry of Norway, Institute of Population-Based Cancer Research,Folkhälsan Research Center
Dartois, Laureen (författare)
University of Paris-Saclay
His, Mathilde (författare)
University of Paris-Saclay
Boutron-Ruault, Marie-Christine (författare)
University of Paris-Saclay
Turzanski-Fortner, Renée (författare)
German Cancer Research Centre
Kaaks, Rudolf (författare)
German Cancer Research Centre
Overvad, Kim (författare)
Aarhus University,Aalborg University Hospital
Redondo, María Luisa (författare)
Public Health Directorate
Travier, Noemie (författare)
Catalan Institute of Oncology
Molina-Portillo, Elena (författare)
CIBER Epidemiology and Public Health (CIBERESP),University of Granada
Dorronsoro, Miren (författare)
CIBER Epidemiology and Public Health (CIBERESP)
Cirera, Lluis (författare)
Murcia Regional Health Council
Ardanaz, Eva (författare)
Navara Public Health Institute,CIBER Epidemiology and Public Health (CIBERESP)
Perez-Cornago, Aurora (författare)
University of Oxford
Trichopoulou, Antonia (författare)
National and Kapodistrian University of Athens,Hellenic Health Foundation, Athens
Lagiou, Pagona (författare)
Harvard University,Hellenic Health Foundation, Athens,National and Kapodistrian University of Athens
Valanou, Elissavet (författare)
Hellenic Health Foundation, Athens
Masala, Giovanna (författare)
Cancer Research and Prevention Institute (ISPO)
Pala, Valeria (författare)
Istituto Nazionale dei Tumori
Peeters, Petra H. M. (författare)
University Medical Center Utrecht
van der Schouw, Yvonne T. (författare)
University Medical Center Utrecht
Melander, Olle (författare)
Lund University,Lunds universitet,Institutionen för kliniska vetenskaper, Malmö,Medicinska fakulteten,Department of Clinical Sciences, Malmö,Faculty of Medicine
Manjer, Jonas (författare)
Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups
da Silva, Marisa (författare)
UiT The Arctic University of Norway, Tromsø
Skeie, Guri (författare)
UiT The Arctic University of Norway, Tromsø
Tjønneland, Anne (författare)
Danish Cancer Society
Olsen, Anja (författare)
Danish Cancer Society
Gunter, Marc J. (författare)
International Agency for Research on Cancer, World Health Organization
Riboli, Elio (författare)
Imperial College London
Cross, Amanda J (författare)
Imperial College London
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 (creator_code:org_t)
2017-03-03
2017
Engelska.
Ingår i: PLoS ONE. - : Public Library of Science (PLoS). - 1932-6203. ; 12:3
Relaterad länk:
http://dx.doi.org/10... (free)
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https://journals.plo...
https://lup.lub.lu.s...
https://doi.org/10.1...
http://kipublication...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Adult height and sitting height may reflect genetic and environmental factors, including early life nutrition, physical and social environments. Previous studies have reported divergent associations for height and chronic disease mortality, with positive associations observed for cancer mortality but inverse associations for circulatory disease mortality. Sitting height might be more strongly associated with insulin resistance; however, data on sitting height and mortality is sparse. Using the European Prospective Investigation into Cancer and Nutrition study, a prospective cohort of 409,748 individuals, we examined adult height and sitting height in relation to all-cause and cause-specific mortality. Height was measured in the majority of participants; sitting height was measured in 253,000 participants. During an average of 12.5 years of follow-up, 29,810 deaths (11,931 from cancer and 7,346 from circulatory disease) were identified. Hazard ratios (HR) with 95% confidence intervals (CI) for death were calculated using multivariable Cox regression within quintiles of height. Height was positively associated with cancer mortality (men: Q5.svQ1 = 1.11, 95%CI = 1.00-1.24; women: Q5.svQ1 = 1.17, 95%CI = 1.07-1.28). In contrast, height was inversely associated with circulatory disease mortality (men: Q5.svQ1 = 0.63, 95%CI = 0.56-0.71; women: vs.1Q= 0.81, 95%CI = 0.70-0.93). Although sitting height was not associated with cancer mortality, it was inversely associated with circulatory disease (men: Q5.svQ1 = 0.64, 95%CI = 0.55-0.75; women: vs.1Q= 0.60, 95%CI = 0.49-0.74) and respiratory disease mortality (men: Q5.svQ1 = 0.45, 95%CI = 0.28-0.71; women: vs.1Q= 0.60, 95%CI = 0.40-0.89). We observed opposing effects of height on cancer and circulatory disease mortality. Sitting height was inversely associated with circulatory disease and respiratory disease mortality.

Nyckelord

cancer
Nutrition
mortality
attained height
sitting height

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art (ämneskategori)
ref (ämneskategori)

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