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Use of Linked Nordi...
Use of Linked Nordic Registries for Population Studies in Hematologic Cancers: The Case of Multiple Myeloma
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- Abildgaard, Niels (författare)
- Hematology Research Unit, Department of Hematology, Odense University Hospital, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense, Denmark
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- Freilich, Jonatan (författare)
- Umeå University,Umeå universitet,Dermatologi och venereologi,Department of Access Consulting, PAREXEL International, Stockholm, Sweden
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- Anttila, Pekka (författare)
- Comprehensive Cancer Center, Department of Hematology, University of Helsinki, Helsinki University Hospital, Helsinki, Finland
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- Bent-Ennakhil, Nawal (författare)
- Takeda Pharmaceuticals International AG, Zurich, Switzerland
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- Ma, Yuanjun (författare)
- Department of Access Consulting, PAREXEL International, Stockholm, Sweden
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- Lassenius, Mariann (författare)
- Medaffcon, Espoo, Finland
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- Ørstavik, Sigurd (författare)
- Takeda Pharmaceuticals International AG, Oslo, Norway
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- Toppila, Iiro (författare)
- Medaffcon, Espoo, Finland
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- Waage, Anders (författare)
- Department of Hematology, St Olav’s University Hospital, Trondheim, Norway
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- Turesson, Ingemar (författare)
- Lund University,Lunds universitet,Myelomgruppen,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Myeloma research group,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital
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- Hansson, Markus (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine,Sahlgrenska Academy and Sahlgrenska University Hospital, Göteborg, Sweden
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(creator_code:org_t)
- Dove Medical Press, 2023
- 2023
- Engelska.
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Ingår i: Clinical Epidemiology. - : Dove Medical Press. - 1179-1349. ; 15, s. 987-999
- Relaterad länk:
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https://doi.org/10.2...
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https://umu.diva-por... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://gup.ub.gu.se...
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https://doi.org/10.2...
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https://urn.kb.se/re...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- Purpose: Linked health-care registries and high coverage in Nordic countries lend themselves well to epidemiologic research. Given its relatively high incidence in Western Europe, complexity in diagnosis, and challenges in registration, multiple myeloma (MM) wasselected to compare registries in Denmark, Finland, and Sweden.Patients and Methods: Data were obtained from four archetypal registries in each country (spanning January 2005–October 2018):National Patient Registry (NPR), Prescribed Drug Registry (PDR), Cancer Registry (CR), and Cause of Death Registry. Patients newlydiagnosed with MM who received MM-specific treatment were included. PDR/NPR treatment records were used to assess incidentNPR cases. The registration quality of MM-specific drugs in the PDR of each country was also evaluated.Results: In Denmark, only 6% of patients in the NPR were not registered in the CR; in Sweden, it was 16.9%. No systematicdifferences were identified that could explain this discrepancy. In Denmark, lenalidomide and bortezomib were registered in the NPRwith high coverage, but less expensive drugs typically given in combination with bortezomib were not covered in any of the registries.In Finland and Sweden, bortezomib records were not identified in the PDR, but some were in the NPR; other drugs had good coveragein the PDR.Conclusions: The registries evaluated in this study can be used to identify the MM population; however, given the gaps in MMregistration in the Finnish and Swedish CRs, Danish registries provide the most comprehensive datasets for research on treatmentpatterns for MM.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Samhällsfarmaci och klinisk farmaci (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Social and Clinical Pharmacy (hsv//eng)
Nyckelord
- incidence
- prevalence
- real-world evidence
- incidence
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- ref (ämneskategori)
- art (ämneskategori)
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Abildgaard, Niel ...
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Freilich, Jonata ...
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Anttila, Pekka
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Bent-Ennakhil, N ...
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Ma, Yuanjun
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Lassenius, Maria ...
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Ørstavik, Sigurd
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Toppila, Iiro
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Waage, Anders
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Turesson, Ingema ...
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Hansson, Markus
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Göteborgs universitet
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Umeå universitet
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Lunds universitet