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The Microbiology of...
The Microbiology of Infective Native Aortic Aneurysms in a Population-Based Setting
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- Sorelius, Karl (author)
- Uppsala universitet,Institutionen för kirurgiska vetenskaper,Rigshosp, Dept Vasc Surg, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.;Univ Copenhagen, Fac Hlth & Med Sci, Copenhagen, Denmark.
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- Wanhainen, Anders (author)
- Uppsala universitet,Kärlkirurgi
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- Furebring, Mia (author)
- Uppsala universitet,Infektionsmedicin
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- Mani, Kevin, 1975- (author)
- Uppsala universitet,Kärlkirurgi
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- Resch, T. (author)
- Rigshosp, Dept Vasc Surg, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.;Univ Copenhagen, Fac Hlth & Med Sci, Copenhagen, Denmark.
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- Hultgren, R. (author)
- Karolinska Institutet,Karolinska Hosp, Dept Vasc Surg, Stockholm, Sweden.,Sahlgrens Univ Hosp, Dept Hybrid & Intervent Surg, Unit Vasc Surg, Gothenburg, Sweden.
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- Wahlgren, C. M. (author)
- Karolinska Institutet,Karolinska Hosp, Dept Vasc Surg, Stockholm, Sweden.,Reg Hosp Sundsvall, Dept Surg, Sundsvall, Sweden.
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- Roos, H. (author)
- Sahlgrens Univ Hosp, Dept Hybrid & Intervent Surg, Unit Vasc Surg, Gothenburg, Sweden.
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- Ojersjo, A. (author)
- Kalmar Hosp, Dept Surg, Kalmar, Sweden.
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- Lindström, David (author)
- Uppsala universitet,Kärlkirurgi
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- Vaccarino, R. (author)
- Skane Univ Hosp, Vasc Ctr, Malmö, Sweden.
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- Arvidsson, B. (author)
- Linköping Univ, Dept Thorac & Vasc Surg, Linköping, Sweden.;Linköping Univ, Dept Med & Hlth Sci, Linköping, Sweden.,Västerås Hosp, Dept Vasc Surg, Västerås, Sweden.
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- Bilos, L. (author)
- Örebro Univ Hosp, Fac Med & Vasc Surg, Dept Cardiothorac & Vasc Surg, Örebro, Sweden.
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- Pirouzram, A. (author)
- Örebro Univ Hosp, Fac Med & Vasc Surg, Dept Cardiothorac & Vasc Surg, Örebro, Sweden.
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- Arnerlov, C. (author)
- Umeå Univ Hosp, Dept Surg & Perioperat Sci, Surg, Umeå, Sweden.
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- Simo, G. (author)
- Cent Hosp Karlstad, Dept Surg, Karlstad, Sweden.
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- Svensson, M. (author)
- Falun Cent Hosp, Dept Surg, Falun, Sweden.,NU Hospitalgrp, Dept Surg, Trollhättan Uddevalla, Sweden.
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- Magnusson, J. (author)
- Helsingborg Hosp, Dept Surg, Helsingborg, Sweden.
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- Astrand, H. (author)
- Jönköping Hosp, Dept Surg, Jönköping, Sweden.
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- Palm, M. (author)
- Sunderby Hosp, Dept Surg, Sunderbyn, Sweden.
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- Holsti, M. (author)
- Umeå Univ Hosp, Dept Surg & Perioperat Sci, Surg, Umeå, Sweden.
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- Mellander, S. (author)
- NU Hospitalgrp, Dept Surg, Trollhättan Uddevalla, Sweden.
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- Korman, D. (author)
- Östersunds Hosp, Dept Surg, Östersund, Sweden.,Gävle Cent Hosp, Dept Surg, Gävle, Sweden.
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- Djavani-Gidlund, K. (author)
- Gävle Cent Hosp, Dept Surg, Gävle, Sweden.
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- Huss, M. (author)
- Karolinska Hosp, Dept Vasc Surg, Stockholm, Sweden.
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- Bertszel, A. (author)
- Västerås Hosp, Dept Vasc Surg, Västerås, Sweden.
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- Docter, M. (author)
- Hudiksvall Hosp, Dept Surg, Hudiksvall, Sweden.
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- Drott, C. (author)
- Borås Hosp, Dept Surg, Borås, Sweden.
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- Nelzen, O. (author)
- Skaraborg Hosp, Dept Vasc Surg, Skoevde, Sweden.
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- Wetterling, T. (author)
- Kristianstad Hosp, Dept Surg, Kristianstad, Sweden.
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- Chu, M. (author)
- Reg Hosp Sundsvall, Dept Surg, Sundsvall, Sweden.
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- Gilgen, N-P (author)
- Karolinska Institutet,Malar Hosp, Dept Surg, Eskilstuna, Sweden.,Soder Sjukhuset, Karolinska Inst, Dept Clin Sci & Educ, Stockholm, Sweden.;Soder Sjukhuset, Unit Vasc Surg, Dept Surg, Stockholm, Sweden.
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- Gillgren, P. (author)
- Soder Sjukhuset, Karolinska Inst, Dept Clin Sci & Educ, Stockholm, Sweden.;Soder Sjukhuset, Unit Vasc Surg, Dept Surg, Stockholm, Sweden.
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(creator_code:org_t)
- Elsevier, 2022
- 2022
- English.
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In: Annals of Vascular Surgery. - : Elsevier. - 0890-5096 .- 1615-5947. ; 78, s. 112-122
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Objective: The aim was to describe the microbiology of surgically treated infective native (mycotic) aortic aneurysms (INAAs), and associated survival and development of infection-related complications (IRCs). Methods: Data were pooled from 2 nationwide studies on surgically treated patients with INAAs in Sweden, between 1994 - 2016. Patients were grouped and analyzed according to culture results: 1) Staphylococcus aureus, 2) Streptococcus species (sp.), 3) Salmonella sp., 4) Enterococcus sp., 5) Gram-negative intestinal bacteria, 6) Other sp. (all other species found in culture), and 7) Negative cultures. Results: A sum of 182 patients were included, mean age 71 years (standard deviation; SD: 8.9). The median follow-up was 50.3 months (range 0 - 360). 128 (70.3%) patients had positive blood and/or tissue culture; Staphylococcus aureus n = 38 (20.9%), Streptococcus sp. n = 37 (20.3%), Salmonella sp. n = 19 (10.4%), Enterococcus sp. n = 16 (8.8%), Gram-negative intestinal bacteria n = 6, (3.3%), Other sp. n = 12 (6.6%) and Negative cultures n = 54 (29.7%). The estimated survival for the largest groups at 2-years after surgery was: Staphylococcus aureus 62% (95% Confidence interval 53.9 - 70.1), Streptococcus sp. 74.7% (67.4 - 82.0), Salmonella sp. 73.7% (63.6 - 83.8), Enterococcus sp. 61.9% (49.6 - 74.2), and Negative cultures 89.8% (85.5 - 94.1), P =.051. There were 37 IRCs (20.3%), and 19 (51.4%) were fatal, the frequency was insignificant between the groups. The majority of IRCs, 30/37 (81%), developed during the first postoperative year. Conclusion: In this assessment of microbiological findings of INAAs in Sweden, 50% of the pathogens were Staphylococcus aureus, Streptococcus sp., or Salmonella sp.. The overall 20%-frequency of IRCs, and its association with high mortality, motivates long-term antibiotic treatment regardless of microbial findings.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Infektionsmedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Infectious Medicine (hsv//eng)
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Sorelius, Karl
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Wanhainen, Ander ...
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Furebring, Mia
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Mani, Kevin, 197 ...
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Resch, T.
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Hultgren, R.
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show more...
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Wahlgren, C. M.
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Roos, H.
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Ojersjo, A.
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Lindström, David
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Vaccarino, R.
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Arvidsson, B.
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Bilos, L.
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Pirouzram, A.
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Arnerlov, C.
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Simo, G.
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Svensson, M.
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Magnusson, J.
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Astrand, H.
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Palm, M.
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Holsti, M.
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Mellander, S.
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Korman, D.
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Djavani-Gidlund, ...
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Huss, M.
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Bertszel, A.
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Docter, M.
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Drott, C.
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Nelzen, O.
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Wetterling, T.
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Chu, M.
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Gilgen, N-P
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Gillgren, P.
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Surgery
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Infectious Medic ...
- Articles in the publication
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Annals of Vascul ...
- By the university
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Uppsala University
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Karolinska Institutet