Sökning: onr:"swepub:oai:gup.ub.gu.se/86296" >
Cerebrospinal fluid...
Cerebrospinal fluid protein reactions during non-neurological surgery.
-
Anckarsäter, Rolf, 1956 (författare)
-
Vasic, N (författare)
-
- Jidéus, Lena (författare)
- Uppsala universitet,Thoraxkirurgi,Thorac Surgery
-
visa fler...
-
- Kristiansson, M (författare)
- Karolinska Institutet
-
- Zetterberg, Henrik, 1973 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
-
- Blennow, Kaj, 1958 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
-
- Anckarsäter, Henrik, 1966 (författare)
- Lund University,Lunds universitet,Rättspsykiatri, Malmö,Forskargrupper vid Lunds universitet,Forensic Psychiatry, Malmö,Lund University Research Groups
-
visa färre...
-
(creator_code:org_t)
- Hindawi Limited, 2007
- 2007
- Engelska.
-
Ingår i: Acta neurologica Scandinavica. - : Hindawi Limited. - 0001-6314 .- 1600-0404. ; 115:4, s. 254-9
- Relaterad länk:
-
http://dx.doi.org/10...
-
visa fler...
-
https://gup.ub.gu.se...
-
https://doi.org/10.1...
-
https://lup.lub.lu.s...
-
https://urn.kb.se/re...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- OBJECTIVE: To study changes in cerebrospinal fluid (CSF) protein markers of blood-CSF barrier integrity and immunological reactions during surgical stress. SUBJECTS AND METHODS: Thirty-five patients without neurological or psychiatric disorders undergoing knee replacements had CSF and serum samples drawn from spinal and arterial catheters before, 3 h after and the morning after surgery. RESULTS: Serum albumin decreased during surgery and CSF albumin decreased during and after surgery, and, as a consequence, the CSF/serum albumin ratio decreased significantly during the study period, especially after the intervention. In contrast, CSF concentrations of beta-2-microglobuline (beta2M) increased significantly during surgery and remained high. The CSF general marker beta-trace protein (betaTP) remained unchanged. CONCLUSIONS: Central nervous system protein reactions to a non-neurological surgical intervention include sharply decreased permeability of albumin into the CSF and signs of intrathecal inflammatory activity.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Nyckelord
- Aged
- Aged
- 80 and over
- Arthroplasty
- Replacement
- Knee
- adverse effects
- Cerebrospinal Fluid Proteins
- metabolism
- Female
- Humans
- Intramolecular Oxidoreductases
- blood
- cerebrospinal fluid
- Intraoperative Period
- Lipocalins
- Male
- Middle Aged
- Postoperative Period
- Serum Albumin
- metabolism
- Stress
- Physiological
- blood
- cerebrospinal fluid
- etiology
- beta 2-Microglobulin
- blood
- cerebrospinal fluid
- spinal anaesthesia
- stress
- inflammation
- fluid
- cerebrospinal
- blood-brain barrier
- albumin
- beta-2-microglobuline
- Albumin
- MEDICINE
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas