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Validation of the H...
Validation of the Health Assessment Tool (HAT) based on four aging cohorts from the Swedish National study on Aging and Care
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- Abbadi, Ahmad (författare)
- Karolinska Institute,Karolinska Institutet
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- Kokoroskos, Emmanouil (författare)
- Karolinska Institute
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- Stamets, Matthew (författare)
- Karolinska Institute
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- Vetrano, Davide L. (författare)
- Karolinska Institute,Karolinska Institutet,Stockholm Gerontology Research Center
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- Orsini, Nicola (författare)
- Karolinska Institute
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- Elmståhl, Sölve (författare)
- Lund University,Lunds universitet,Geriatrik,Forskargrupper vid Lunds universitet,Geriatrics,Lund University Research Groups
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- Fagerström, Cecilia, Professor, 1973- (författare)
- Linnaeus University,Linnéuniversitetet,Institutionen för hälso- och vårdvetenskap (HV),Region Kalmar, Sweden
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- Wimo, Anders (författare)
- Karolinska Institute
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- Sköldunger, Anders (författare)
- Karolinska Institute
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- Sanmartin Berglund, Johan, Professor (författare)
- Blekinge Tekniska Högskola,Institutionen för hälsa,Blekinge Institute of Technology, Sweden
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- Olsson, Christina B. (författare)
- Karolinska Institute,Karolinska Institutet,Academic Primary Health Care Center,Aging Research Center
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- Wachtler, Caroline (författare)
- Karolinska Institute,Academic Primary Health Care Center,Aging Research Center
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- Fratiglioni, Laura (författare)
- Karolinska Institute,Stockholm Gerontology Research Center
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- Calderón-Larrañaga, Amaia (författare)
- Karolinska Institute,Stockholm Gerontology Research Center
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(creator_code:org_t)
- BioMed Central (BMC), 2024
- 2024
- Engelska.
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Ingår i: BMC Medicine. - : BioMed Central (BMC). - 1741-7015. ; 22:1
- Relaterad länk:
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https://doi.org/10.1...
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https://bth.diva-por... (primary) (Raw object)
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http://dx.doi.org/10... (free)
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- Background: As global aging accelerates, routinely assessing the functional status and morbidity burden of older patients becomes paramount. The aim of this study is to assess the validity of the comprehensive clinical and functional Health Assessment Tool (HAT) based on four cohorts of older adults (60 + years) from the Swedish National study on Aging and Care (SNAC) spanning urban, suburban, and rural areas.Methods: The HAT integrates five health indicators (gait speed, global cognition, number of chronic diseases, and basic and instrumental activities of daily living), providing an individual-level score between 0 and 10. The tool was constructed using nominal response models, first separately for each cohort and then in a harmonized dataset. Outcomes included all-cause mortality over a maximum follow-up of 16 years and unplanned hospital admissions over a maximum of 3 years of follow-up. The predictive capacity was assessed through the area under the curve (AUC) using logistic regressions. For time to death, Cox regressions were performed, and Harrell’s C-indices were reported. Results from the four cohorts were pooled using individual participant data meta-analysis and compared with those from the harmonized dataset.Results: The HAT demonstrated high predictive capacity across all cohorts as well as in the harmonized dataset. In the harmonized dataset, the AUC was 0.84 (95% CI 0.81–0.87) for 1-year mortality, 0.81 (95% CI 0.80–0.83) for 3-year mortality, 0.80 (95% CI 0.79–0.82) for 5-year mortality, 0.69 (95% CI 0.67–0.70) for 1-year unplanned admissions, and 0.69 (95% CI 0.68–0.70) for 3-year unplanned admissions. The Harrell’s C for time-to-death throughout 16 years of follow-up was 0.75 (95% CI 0.74–0.75).Conclusions: The HAT is a highly predictive, clinically intuitive, and externally valid instrument with potential for better addressing older adults’ health needs and optimizing risk stratification at the population level. © The Author(s) 2024.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Geriatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Geriatrics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Omvårdnad (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nursing (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- Aging cohorts
- External validation
- Frailty
- Geriatric health assessment
- Activities of Daily Living
- Aged
- Aged
- 80 and over
- Aging
- Chronic Disease
- Cohort Studies
- Female
- Geriatric Assessment
- Humans
- Male
- Middle Aged
- Sweden
- adult
- all cause mortality
- area under the curve
- Article
- cognition
- daily life activity
- follow up
- gait
- health care
- hospital admission
- hospitalization
- human
- major clinical study
- Mini Mental State Examination
- mortality
- nurse
- nurse practitioner
- proportional hazards model
- psychologist
- quality of life
- questionnaire
- time series analysis
- validation study
- waist circumference
- cohort analysis
- epidemiology
- procedures
- very elderly
- Omvårdnad
- Aging cohorts
- External validation
- Frailty
- Geriatric health assessment
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Abbadi, Ahmad
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Kokoroskos, Emma ...
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Stamets, Matthew
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Vetrano, Davide ...
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Orsini, Nicola
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Elmståhl, Sölve
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Fagerström, Ceci ...
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Wimo, Anders
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Sköldunger, Ande ...
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Sanmartin Berglu ...
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Olsson, Christin ...
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Wachtler, Caroli ...
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Fratiglioni, Lau ...
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Calderón-Larraña ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Geriatrik
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Omvårdnad
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Folkhälsovetensk ...
- Artiklar i publikationen
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BMC Medicine
- Av lärosätet
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Blekinge Tekniska Högskola
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Linnéuniversitetet
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Karolinska Institutet
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Lunds universitet