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Exploring gender dy...
Exploring gender dysphoria and related outcomes in a prospective cohort study: protocol for the Swedish Gender Dysphoria Study (SKDS)
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- Özel, Faith (author)
- Uppsala universitet,Institutionen för organismbiologi,WoMHeR (Centre for Women’s Mental Health during the Reproductive Lifespan),Uppsala Univ, Sweden
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- Indremo, Malin (author)
- Uppsala universitet,Psykiatri,Uppsala Univ, Sweden
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- Karamanis, Georgios (author)
- Uppsala universitet,Psykiatri,Uppsala Univ, Sweden
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- Elofsson, Ulf (author)
- Uppsala universitet,Obstetrisk och reproduktiv hälsoforskning,Psykiatri,Uppsala Univ, Sweden
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- Beckman, Ulrika (author)
- Department of Psychiatry, Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Psychiat, Gothenburg, Sweden.
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- Fazekas, A. (author)
- Department of Psychiatry, Lund University, Lund, Sweden,Lund Univ, Dept Psychiat, Lund, Sweden.
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- Frisen, L. (author)
- Karolinska Institutet,Karolinska Inst, Dept Clin Neurosci, Stockholm, Sweden.
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- Isaksson, Magnus (author)
- Uppsala universitet,Autoimmunitet,Endokrinologi och mineralmetabolism,Uppsala Univ, Sweden
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- Sandström, Lotta (author)
- Umeå universitet,Psykiatri,ANOVA, Sexual Medicine and Transgender Medicine, Karolinska University Hospital, Stockholm, Sweden,Karolinska Univ Hosp, ANOVA, Androl Sexual Med & Transgender Med, Stockholm, Sweden.;Umeå Univ, Dept Clin Sci, Psychiat, Umeå, Sweden.
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- Thelin, Nils (author)
- Department of Psychiatry, Linköping University Hospital, Linköping, Sweden,Linköping Univ Hosp, Dept Psychiat, Linköping, Sweden.,Region Östergötland, Psykiatriska kliniken i Linköping
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- Tivesten, Åsa, 1969 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,Wallenberg Laboratory for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden,Univ Gothenburg, Sahlgrenska Acad, Wallenberg Lab Cardiovasc & Metab Res, Dept Mol & Clin Med,Inst Med, Gothenburg, Sweden.;Sahlgrens Univ Hosp, Dept Endocrinol, Gothenburg, Sweden.
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- Wahlberg, Jeanette, 1969- (author)
- Örebro universitet,Institutionen för medicinska vetenskaper,Department of Endocrinology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Örebro Univ, Dept Endocrinol, Fac Med & Hlth, Örebro, Sweden.
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- Skalkidou, Alkistis, 1977- (author)
- Uppsala universitet,Institutionen för kvinnors och barns hälsa,Uppsala Univ, Sweden
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- Bodlund, Owe (author)
- Umeå universitet,Psykiatri,Umeå Univ, Dept Clin Sci, Psychiat, Umeå, Sweden.
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- Papadopoulos, F. C. (author)
- Uppsala universitet,Psykiatri,Uppsala Univ, Sweden
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(creator_code:org_t)
- BMJ Publishing Group Ltd, 2023
- 2023
- English.
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In: Bmj Open. - : BMJ Publishing Group Ltd. - 2044-6055. ; 13:4
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Abstract
Subject headings
Close
- Introduction There has been a drastic increase in the reported number of people seeking help for gender dysphoria in many countries over the last two decades. Yet, our knowledge of gender dysphoria and related outcomes is restricted due to the lack of high-quality studies employing comprehensive approaches. This longitudinal study aims to enhance our knowledge of gender dysphoria; different aspects will be scrutinised, focusing primarily on the psychosocial and mental health outcomes, prognostic markers and, secondarily, on the underlying mechanisms for its origin. Methods and analysis The Swedish Gender Dysphoria Study is an ongoing multicentre longitudinal cohort study with 501 registered participants with gender dysphoria who are 15 years old or older. Participants at different phases of their clinical evaluation process can enter the study, and the expected follow-up duration is three years. The study also includes a comparison group of 458 age- and county-matched individuals without gender dysphoria. Data on the core outcomes of the study, which are gender incongruence and experienced gender dysphoria, body satisfaction and satisfaction with gender-affirming treatments, as well as other relevant outcomes, including mental health, social functioning and life satisfaction, are collected via web surveys. Two different research visits, before and after starting on gender-affirming hormonal treatment (if applicable), are planned to collect respective biological and cognitive measures. Data analysis will be performed using appropriate biostatistical methods. A power analysis showed that the current sample size is big enough to analyse continuous and categorical outcomes, and participant recruitment will continue until December 2022. Ethics and dissemination The ethical permission for this study was obtained from the Local Ethical Review Board in Uppsala, Sweden. Results of the study will be presented at national and international conferences and published in peer-reviewed journals. Dissemination will also be implemented through the Swedish Gender Dysphoria Study network in Sweden.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap -- Gerontologi, medicinsk/hälsovetenskaplig inriktning (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences -- Gerontology, specialising in Medical and Health Sciences (hsv//eng)
Keyword
- Child & adolescent psychiatry
- Adult psychiatry
- EPIDEMIOLOGY
- psychometric evaluation
- health
- scale
- transgender
- validation
- questionnaire
- metaanalysis
- disorder
- twins
- life
- General & Internal Medicine
- Adult psychiatry
Publication and Content Type
- ref (subject category)
- art (subject category)
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Özel, Faith
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Indremo, Malin
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Karamanis, Georg ...
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Elofsson, Ulf
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Beckman, Ulrika
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Fazekas, A.
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Frisen, L.
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Isaksson, Magnus
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Sandström, Lotta
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Thelin, Nils
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Tivesten, Åsa, 1 ...
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Wahlberg, Jeanet ...
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Skalkidou, Alkis ...
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Bodlund, Owe
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Papadopoulos, F. ...
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