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CSF monoamine metab...
CSF monoamine metabolites in relation to the diagnostic interview for borderline patients (DIB)
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- Chotai, Jayanti (författare)
- Umeå universitet,Psykiatri
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- Kullgren, Gunnar (författare)
- Umeå universitet,Psykiatri
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- Asberg, M (författare)
- Karolinska Institutet
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(creator_code:org_t)
- 1998-11-09
- 1998
- Engelska.
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Ingår i: Neuropsychobiology. - : S. Karger AG. - 0302-282X .- 1423-0224. ; 38:4, s. 207-212
- Relaterad länk:
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http://kipublication...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- The cerebrospinal fluid concentrations of the monoamine metabolites 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA), 3-methoxy-4-hydroxyphenylglycol, and their ratios were studied in relation to the Diagnostic Interview for Borderline patients (DIB) evaluated retrospectively from hospital records for a sample of 202 patients participating in psychobiological programs on mood disorders. No correlations with the total DIB score were significant. Patients with borderline personality disorder (BPD) defined by a total DIB score of at least 7 or 6, respectively, did not differ significantly from non-BPD regarding the metabolites. However, for section II (impulse action pattern) of the DIB, those with an intermediate value of the section score had significantly higher levels of 5-HIAA and HVA, suggesting that such higher than normal concentrations may be protective against impulsive or suicidal behavior generated by an underlying psychiatric morbidity due to other risk factors.
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- art (ämneskategori)
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