Clinical outcome in bipolar disorder in a community-based follow-up study in Butajira, Ethiopia

Fekadu, AbebawInstitute of Psychiatry, Kings College London, London (författare)

Objective: To determine the clinical outcome of bipolar disorder in a developing country setup. Method: After assessing 68 378 individuals, aged 15–49 years, in a double-sampling design in a rural community in Ethiopia, 312 patients with bipolar disorder were prospectively monitored with symptom rating scales and clinically for an average of 2.5 years. Results: Overall, 65.9% of the cohort experienced a relapse – 47.8% manic, 44.3% depressive and 7.7% mixed episodes – and 31.1% had persistent illness. Female gender predicted depressive relapse, while male gender predicted manic relapse. Being on psychotropic medication was associated with remission. Conclusion: This large community-based study confirms the relapsing nature of bipolar disorder and a tendency for chronicity. This may be partly because of lack of appropriate interventions in this setting; however, it may also indicate the underlying severity of the disorder irrespective of setting.

Kebede, DCommunity Health, Addis Ababa University, Addis Ababa, Ethiopia (författare)
Alem, APsychiatry, Addis Ababa University, Addis Ababa, Ethiopia (författare)
Fekadu, DInstitute of Psychiatry, Kings College London, London (författare)
Mogga, SInstitute of Psychiatry, Kings College London, London (författare)
Negash, Alemayehu,1962-Psychiatry, Addis Ababa University, Addis Ababa, Ethiopia (författare)
Medhin, GPathobiology, Addis Ababa University, Addis Ababa, Ethiopia (författare)
Beyero, TCommunity Health, Addis Ababa University, Addis Ababa, Ethiopia (författare)
Shibre, TPsychiatry, Addis Ababa University, Addis Ababa, Ethiopia (författare)
Institute of Psychiatry, Kings College London, LondonCommunity Health, Addis Ababa University, Addis Ababa, Ethiopia (creator_code:org_t)

Ingår i:Acta Psychiatrica Scandinavica: Wiley114:6, s. 426-4340001-690X1600-0447

Av författaren/redakt...: Fekadu, Abebaw; Kebede, D; Alem, A; Fekadu, D; Mogga, S; Negash, Alemayeh ...; visa fler...; Medhin, G; Beyero, T; Shibre, T; visa färre...

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Psykiatri

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