SwePub
Sök i LIBRIS databas

  Utökad sökning

onr:"swepub:oai:DiVA.org:umu-224181"
 

Sökning: onr:"swepub:oai:DiVA.org:umu-224181" > Fine-mapping analys...

Fine-mapping analysis including over 254 000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes

Chen, Zhishan (författare)
Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States
Guo, Xingyi (författare)
Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States; Department of Biomedical Informatics, Vanderbilt University School of Medicine, TN, Nashville, United States
Tao, Ran (författare)
Department of Biostatistics, Vanderbilt University Medical Center, TN, Nashville, United States; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, TN, Nashville, United States
visa fler...
Huyghe, Jeroen R. (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States
Law, Philip J. (författare)
Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom
Fernandez-Rozadilla, Ceres (författare)
Edinburgh Cancer Research Centre, Institute of Genomics and Cancer, University of Edinburgh, Edinburgh, United Kingdom; Genomic Medicine Group, Instituto de Investigacion Sanitaria de Santiago, Santiago de Compostela, Spain
Ping, Jie (författare)
Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States
Jia, Guochong (författare)
Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States
Long, Jirong (författare)
Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States
Li, Chao (författare)
Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States
Shen, Quanhu (författare)
Department of Biostatistics, Vanderbilt University Medical Center, TN, Nashville, United States
Xie, Yuhan (författare)
Department of Biostatistics, Yale School of Public Health, CT, New Haven, United States
Timofeeva, Maria N. (författare)
Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom; Danish Institute for Advanced Study, Department of Public Health, University of Southern Denmark, Odense, Denmark
Thomas, Minta (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States
Schmit, Stephanie L. (författare)
Genomic Medicine Institute, Cleveland Clinic, OH, Cleveland, United States; Population and Cancer Prevention Program, Case Comprehensive Cancer Center, OH, Cleveland, United States
Díez-Obrero, Virginia (författare)
Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute, Barcelona, Spain; Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Spain; Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona, Spain; Oncology Data Analytics Program, Catalan Institute of Oncology, Barcelona, Spain
Devall, Matthew (författare)
Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, VA, Charlottesville, United States
Moratalla-Navarro, Ferran (författare)
Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute, Barcelona, Spain; Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Spain; Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona, Spain; Oncology Data Analytics Program, Catalan Institute of Oncology, Barcelona, Spain
Fernandez-Tajes, Juan (författare)
Edinburgh Cancer Research Centre, Institute of Genomics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
Palles, Claire (författare)
Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom
Sherwood, Kitty (författare)
Edinburgh Cancer Research Centre, Institute of Genomics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
Briggs, Sarah E. W. (författare)
Department of Public Health, Richard Doll Building, University of Oxford, Oxford, United Kingdom
Svinti, Victoria (författare)
Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
Donnelly, Kevin (författare)
Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
Farrington, Susan M. (författare)
Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
Blackmur, James (författare)
Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
Vaughan-Shaw, Peter G. (författare)
Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
Shu, Xiao-Ou (författare)
Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States
Lu, Yingchang (författare)
Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States
Broderick, Peter (författare)
Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom
Studd, James (författare)
Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom
Harrison, Tabitha A. (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States
Conti, David V. (författare)
Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States
Schumacher, Fredrick R. (författare)
Case Comprehensive Cancer Center, Case Western Reserve University, OH, Cleveland, United States; Department of Population and Quantitative Health Sciences, Case Western Reserve University, OH, Cleveland, United States
Melas, Marilena (författare)
The Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children’s Hospital, OH, Columbus, United States
Rennert, Gad (författare)
Clalit National Cancer Control Center, Haifa, Israel; Department of Community Medicine and Epidemiology, Lady Davis Carmel Medical Center, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
Obón-Santacana, Mireia (författare)
Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute, Barcelona, Spain; Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Spain; Oncology Data Analytics Program, Catalan Institute of Oncology, Barcelona, Spain
Martín-Sánchez, Vicente (författare)
Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Spain; Biomedicine Institute, University of León, León, Spain
Oh, Jae Hwan (författare)
Center for Colorectal Cancer, National Cancer Center Hospital, National Cancer Center, Gyeonggi-do, South Korea
Kim, Jeongseon (författare)
Department of Cancer Biomedical Science, Graduate School of Cancer Science and Policy, National Cancer Center, Gyeonggi-do, South Korea
Jee, Sun Ha (författare)
Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, South Korea
Jung, Keum Ji (författare)
Department of Epidemiology and Health Promotion, Graduate School of Public Health, Yonsei University, Seoul, South Korea
Kweon, Sun-Seog (författare)
Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, South Korea
Shin, Min-Ho (författare)
Department of Preventive Medicine, Chonnam National University Medical School, Gwangju, South Korea
Shin, Aesun (författare)
Cancer Research Institute, Seoul National University, Seoul, South Korea; Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, South Korea
Ahn, Yoon-Ok (författare)
Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, South Korea
Kim, Dong-Hyun (författare)
Department of Social and Preventive Medicine, Hallym University College of Medicine, Okcheon-dong, South Korea
Oze, Isao (författare)
Division of Cancer Epidemiology and Prevention, Aichi Cancer Center Research Institute, Nagoya, Japan
Wen, Wanqing (författare)
Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States
Matsuo, Keitaro (författare)
Department of Epidemiology, Nagoya University Graduate School of Medicine, Nagoya, Japan; Division of Molecular and Clinical Epidemiology, Aichi Cancer Center Research Institute, Nagoya, Japan
Matsuda, Koichi (författare)
Laboratory of Clinical Genome Sequencing, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, University of Tokyo, Tokyo, Japan
Tanikawa, Chizu (författare)
Laboratory of Genome Technology, Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan
Ren, Zefang (författare)
School of Public Health, Sun Yat-sen University, Guangzhou, China
Gao, Yu-Tang (författare)
State Key Laboratory of Oncogenes and Related Genes and Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
Jia, Wei-Hua (författare)
State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat-sen University, Guangzhou, China
Hopper, John L. (författare)
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, VIC, Melbourne, Australia; Department of Epidemiology, School of Public Health and Institute of Health and Environment, Seoul National University, Seoul, South Korea
Jenkins, Mark A. (författare)
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, VIC, Melbourne, Australia
Win, Aung Ko (författare)
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, VIC, Melbourne, Australia
Pai, Rish K. (författare)
Department of Laboratory Medicine and Pathology, Mayo Clinic Arizona, AZ, Scottsdale, United States
Figueiredo, Jane C. (författare)
Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States; Department of Medicine, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, CA, Los Angeles, United States
Haile, Robert W. (författare)
Division of Oncology, Department of Medicine, Cedars-Sinai Cancer Research Center for Health Equity, CA, Los Angeles, United States
Gallinger, Steven (författare)
Lunenfeld Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, ON, Toronto, Canada
Woods, Michael O. (författare)
Division of Biomedical Sciences, Memorial University of Newfoundland, ON, St. John, Canada
Newcomb, Polly A. (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States; School of Public Health, University of Washington, WA, Seattle, United States
Duggan, David (författare)
City of Hope National Medical Center, Translational Genomics Research Institute, AZ, Phoenix, United States
Cheadle, Jeremy P. (författare)
Institute of Medical Genetics, Cardiff University, Cardiff, United Kingdom
Kaplan, Richard (författare)
MRC Clinical Trials Unit, Medical Research Council, Cardiff, United Kingdom
Kerr, Rachel (författare)
Department of Oncology, University of Oxford, Oxford, United Kingdom
Kerr, David (författare)
Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
Kirac, Iva (författare)
Department of Surgical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Böhm, Jan (författare)
Department of Pathology, Central Finland Health Care District, Jyväskylä, Finland
Mecklin, Jukka-Pekka (författare)
Central Finland Health Care District, Jyväskylä, Finland
Jousilahti, Pekka (författare)
Department of Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland
Knekt, Paul (författare)
Department of Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland
Aaltonen, Lauri A. (författare)
Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland; Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland
Rissanen, Harri (författare)
Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland
Pukkala, Eero (författare)
Faculty of Social Sciences, Tampere University, Tampere, Finland; Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland
Eriksson, Johan G. (författare)
Folkhälsan Research Centre, University of Helsinki, Helsinki, Finland; Human Potential Translational Research Programme, National University of Singapore, Singapore, Singapore; Unit of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Cajuso, Tatiana (författare)
Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland; Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland
Hänninen, Ulrika (författare)
Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland; Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland
Kondelin, Johanna (författare)
Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland; Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland
Palin, Kimmo (författare)
Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland; Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland
Tanskanen, Tomas (författare)
Department of Medical and Clinical Genetics, University of Helsinki, Helsinki, Finland; Genome-Scale Biology Research Program, University of Helsinki, Helsinki, Finland
Renkonen-Sinisalo, Laura (författare)
Department of Surgery, Abdominal Centre, Helsinki University Hospital, Helsinki, Finland
Männistö, Satu (författare)
Department of Public Health and Welfare, Finnish Institute for Health and Welfare, Helsinki, Finland
Albanes, Demetrius (författare)
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States
Weinstein, Stephanie J. (författare)
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States
Ruiz-Narvaez, Edward (författare)
Department of Nutritional Sciences, School of Public Health, University of Michigan, MI, Ann Arbor, United States
Palmer, Julie R. (författare)
Department of Medicine, Boston University School of Medicine, MA, Boston, United States; Slone Epidemiology Center at Boston University, MA, Boston, United States
Buchanan, Daniel D. (författare)
Colorectal Oncogenomics Group, Department of Clinical Pathology, University of Melbourne, VIC, Parkville, Australia; Genomic Medicine and Family Cancer Clinic, Royal Melbourne Hospital, VIC, Parkville, Australia; University of Melbourne Centre for Cancer Research, Victorian Comprehensive Cancer Centre, VIC, Parkville, Australia
Platz, Elizabeth A. (författare)
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, MD, Baltimore, United States
Visvanathan, Kala (författare)
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, MD, Baltimore, United States
Ulrich, Cornelia M. (författare)
Huntsman Cancer Institute and Department of Population Health Sciences, University of Utah, UT, Salt Lake City, United States
Siegel, Erin (författare)
Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, FL, Tampa, United States
Brezina, Stefanie (författare)
Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria
Gsur, Andrea (författare)
Institute of Cancer Research, Department of Medicine I, Medical University Vienna, Vienna, Austria
Campbell, Peter T. (författare)
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, NY, New York, United States
Chang-Claude, Jenny (författare)
Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany; University Medical Centre Hamburg-Eppendorf, University Cancer Centre Hamburg, Hamburg, Germany
Hoffmeister, Michael (författare)
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
Brenner, Hermann (författare)
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany; Division of Preventive Oncology, German Cancer Research Center and National Center for Tumor Diseases, Heidelberg, Germany; German Cancer Consortium, German Cancer Research Center, Heidelberg, Germany
Slattery, Martha L. (författare)
Department of Internal Medicine, University of Utah, UT, Salt Lake City, United States
Potter, John D. (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States; Research Centre for Hauora and Health, Massey University, Wellington, New Zealand
Tsilidis, Kostas K. (författare)
Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom; Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
Schulze, Matthias B. (författare)
Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany; Institute of Nutritional Science, University of Potsdam, Potsdam, Germany
Gunter, Marc J. (författare)
Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France
Murphy, Neil (författare)
Nutrition and Metabolism Branch, International Agency for Research on Cancer, World Health Organization, Lyon, France
Castells, Antoni (författare)
Gastroenterology Department, Hospital Clínic, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University of Barcelona, Barcelona, Spain
Castellví-Bel, Sergi (författare)
Gastroenterology Department, Hospital Clínic, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University of Barcelona, Barcelona, Spain
Moreira, Leticia (författare)
Gastroenterology Department, Hospital Clínic, Institut d’Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, University of Barcelona, Barcelona, Spain
Arndt, Volker (författare)
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
Shcherbina, Anna (författare)
Department of Genetics, Stanford University, CA, Stanford, United States
Bishop, D. Timothy (författare)
Leeds Institute of Medical Research at St James’s, University of Leeds, Leeds, United Kingdom
Giles, Graham G. (författare)
Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, VIC, Melbourne, Australia; Cancer Epidemiology Division, Cancer Council Victoria, VIC, Melbourne, Australia; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, VIC, Clayton, Australia
Southey, Melissa C. (författare)
Cancer Epidemiology Division, Cancer Council Victoria, VIC, Melbourne, Australia; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, VIC, Clayton, Australia; Department of Clinical Pathology, University of Melbourne, VIC, Melbourne, Australia
Idos, Gregory E. (författare)
Department of Medical Oncology and Center For Precision Medicine, City of Hope National Medical Center, CA, Duarte, United States
McDonnell, Kevin J. (författare)
Clalit National Cancer Control Center, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel; Department of Medical Oncology and Center For Precision Medicine, City of Hope National Medical Center, CA, Duarte, United States
Abu-Ful, Zomoroda (författare)
Department of Community Medicine and Epidemiology, Lady Davis Carmel Medical Center, Haifa, Israel
Greenson, Joel K. (författare)
Clalit National Cancer Control Center, Haifa, Israel; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel; Department of Pathology, University of Michigan, MI, Ann Arbor, United States
Shulman, Katerina (författare)
Department of Community Medicine and Epidemiology, Lady Davis Carmel Medical Center, Haifa, Israel
Lejbkowicz, Flavio (författare)
Clalit National Cancer Control Center, Haifa, Israel; Department of Community Medicine and Epidemiology, Lady Davis Carmel Medical Center, Haifa, Israel; Clalit Health Services, Personalized Genomic Service, Lady Davis Carmel Medical Center, Haifa, Israel
Offit, Kenneth (författare)
Clinical Genetics Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, NY, New York, United States; Department of Medicine, Weill Cornell Medical College, NY, New York, United States
Su, Yu-Ru (författare)
Kaiser Permanente Washington Health Research Institute, WA, Seattle, United States
Steinfelder, Robert (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States
Keku, Temitope O. (författare)
Center for Gastrointestinal Biology and Disease, University of North Carolina, NC, Chapel Hill, United States
van Guelpen, Bethany (författare)
Umeå universitet,Wallenberg centrum för molekylär medicin vid Umeå universitet (WCMM),Onkologi
Hudson, Thomas J. (författare)
Ontario Institute for Cancer Research, ON, Toronto, Canada
Hampel, Heather (författare)
Division of Human Genetics, Department of Internal Medicine, Ohio State University Comprehensive Cancer Center, OH, Columbus, United States
Pearlman, Rachel (författare)
Division of Human Genetics, Department of Internal Medicine, Ohio State University Comprehensive Cancer Center, OH, Columbus, United States
Berndt, Sonja I. (författare)
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States
Hayes, Richard B. (författare)
Division of Epidemiology, Department of Population Health, New York University School of Medicine, NY, New York, United States
Martinez, Marie Elena (författare)
Department of Family Medicine and Public Health, University of California San Diego, La Jolla, CA, United States; Population Sciences, Disparities and Community Engagement, University of California San Diego Moores Cancer Center, La Jolla, CA, United States
Thomas, Sushma S. (författare)
Fred Hutchinson Cancer Center, WA, Seattle, United States
Pharoah, Paul D. P. (författare)
Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom
Larsson, Susanna C. (författare)
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Yen, Yun (författare)
Taipei Medical University, Taipei, Taiwan
Lenz, Heinz-Josef (författare)
Department of Medicine, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States
White, Emily (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States; Department of Epidemiology, University of Washington School of Public Health, WA, Seattle, United States
Li, Li (författare)
Case Comprehensive Cancer Center, Case Western Reserve University, OH, Cleveland, United States
Doheny, Kimberly F. (författare)
Center for Inherited Disease Research, Department of Genetic Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, United States
Pugh, Elizabeth (författare)
Center for Inherited Disease Research, Department of Genetic Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, United States
Shelford, Tameka (författare)
Center for Inherited Disease Research, Department of Genetic Medicine, Johns Hopkins University School of Medicine, MD, Baltimore, United States
Chan, Andrew T. (författare)
Broad Institute of Harvard and MIT, MA, Cambridge, United States; Channing Division of Network Medicine, Brigham and Women’s Hospital and Harvard Medical School, MA, Boston, United States; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, MA, Boston, United States; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States; Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, MA, Boston, United States
Cruz-Correa, Marcia (författare)
Comprehensive Cancer Center, University of Puerto Rico, San Juan, Puerto Rico
Lindblom, Annika (författare)
Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Hunter, David J. (författare)
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States; Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom
Joshi, Amit D. (författare)
Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, MA, Boston, United States; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States
Schafmayer, Clemens (författare)
Department of General Surgery, University Hospital Rostock, Rostock, Germany
Scacheri, Peter C. (författare)
Department of Genetics and Genome Sciences, Case Western Reserve University, OH, Cleveland, United States
Kundaje, Anshul (författare)
Department of Genetics, Stanford University, CA, Stanford, United States; Department of Computer Science, Stanford University, CA, Stanford, United States
Schoen, Robert E. (författare)
Department of Medicine and Epidemiology, University of Pittsburgh Medical Center, PA, Pittsburgh, United States
Hampe, Jochen (författare)
Department of Medicine I, University Hospital Dresden, Technische Universität Dresden, Dresden, Germany
Stadler, Zsofia K. (författare)
Department of Medicine, Weill Cornell Medical College, NY, New York, United States; Department of Medicine, Memorial Sloan-Kettering Cancer Center, NY, New York, United States
Vodicka, Pavel (författare)
Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czech Republic; Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic
Vodickova, Ludmila (författare)
Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czech Republic; Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic
Vymetalkova, Veronika (författare)
Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Prague, Czech Republic; Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic
Edlund, Christopher K. (författare)
Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States
Gauderman, W. James (författare)
Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States
Shibata, David (författare)
Department of Surgery, University of Tennessee Health Science Center, TN, Memphis, United States
Toland, Amanda (författare)
Departments of Cancer Biology and Genetics and Internal Medicine, Comprehensive Cancer Center, Ohio State University, OH, Columbus, United States
Markowitz, Sanford (författare)
Departments of Medicine and Genetics, Case Comprehensive Cancer Center, Case Western Reserve University and University Hospitals of Cleveland, OH, Cleveland, United States
Kim, Andre (författare)
Department of Preventive Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States
Chanock, Stephen J. (författare)
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, MD, Bethesda, United States
van Duijnhoven, Franzel (författare)
Division of Human Nutrition and Health, Wageningen University and Research, Wageningen, Netherlands
Feskens, Edith J. M. (författare)
Division of Human Nutrition, Wageningen University and Research, Wageningen, Netherlands
Sakoda, Lori C. (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States; Division of Research, Kaiser Permanente Northern California, CA, Oakland, United States
Gago-Dominguez, Manuela (författare)
Genomic Medicine Group, Galician Public Foundation of Genomic Medicine, Servicio Galego de Saude, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela, Santiago de Compostela, Spain
Wolk, Alicja (författare)
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Pardini, Barbara (författare)
Candiolo Cancer Institute FPO-IRCCS, (TO), Candiolo, Italy; Italian Institute for Genomic Medicine, Candiolo Cancer Institute FPO-IRCCS, (TO), Candiolo, Italy
FitzGerald, Liesel M. (författare)
Cancer Epidemiology Division, Cancer Council Victoria, VIC, Melbourne, Australia; Menzies Institute for Medical Research, University of Tasmania, TAS, Hobart, Australia
Lee, Soo Chin (författare)
National University Cancer Institute, Singapore, Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
Ogino, Shuji (författare)
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, MA, Boston, United States; Broad Institute of MIT and Harvard, MA, Cambridge, United States; Cancer Immunology Program, Dana-Farber Harvard Cancer Center, MA, Boston, United States; Department of Pathology, Brigham and Women’s Hospital, Harvard Medical School, MA, Boston, United States
Bien, Stephanie A. (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States
Kooperberg, Charles (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States
Li, Christopher I. (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States
Lin, Yi (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States
Prentice, Ross (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States; Department of Biostatistics, University of Washington, WA, Seattle, United States
Qu, Conghui (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States
Bézieau, Stéphane (författare)
Service de Génétique Médicale, Centre Hospitalier Universitaire Nantes, Nantes, France
Yamaji, Taiki (författare)
Division of Epidemiology, National Cancer Center Institute for Cancer Control, National Cancer Center, Tokyo, Japan
Sawada, Norie (författare)
Division of Cohort Research, National Cancer Center Institute for Cancer Control, National Cancer Center, Tokyo, Japan
Iwasaki, Motoki (författare)
Division of Epidemiology, National Cancer Center Institute for Cancer Control, National Cancer Center, Tokyo, Japan; Division of Cohort Research, National Cancer Center Institute for Cancer Control, National Cancer Center, Tokyo, Japan
Le Marchand, Loic (författare)
Cancer Center, University of Hawaii, HI, Honolulu, United States
Wu, Anna H. (författare)
Preventative Medicine, University of Southern California, CA, Los Angeles, United States
Qu, Chenxu (författare)
USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States
McNeil, Caroline E. (författare)
USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, CA, Los Angeles, United States
Coetzee, Gerhard (författare)
Van Andel Research Institute, MI, Grand Rapids, United States
Hayward, Caroline (författare)
MRC Human Genetics Unit, Institute of Genomics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
Deary, Ian J. (författare)
Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom
Harris, Sarah E. (författare)
Lothian Birth Cohorts group, Department of Psychology, University of Edinburgh, Edinburgh, United Kingdom
Theodoratou, Evropi (författare)
Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom
Reid, Stuart (författare)
Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
Walker, Marion (författare)
Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
Ooi, Li Yin (författare)
Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom; Department of Pathology, National University Hospital, National University Health System, Singapore, Singapore
Lau, Ken S. (författare)
Epithelial Biology Center and Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, TN, Nashville, United States
Zhao, Hongyu (författare)
Department of Biostatistics, Yale School of Public Health, CT, New Haven, United States; Department of Genetics, Yale School of Medicine, CT, New Haven, United States; Program in Computational Biology and Bioinformatics, Yale University, CT, New Haven, United States
Hsu, Li (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States; Department of Biostatistics, School of Public Health, University of Washington, WA, Seattle, United States
Cai, Qiuyin (författare)
Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States
Dunlop, Malcolm G. (författare)
Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, United Kingdom
Gruber, Stephen B. (författare)
Department of Medical Oncology and Center For Precision Medicine, City of Hope National Medical Center, CA, Duarte, United States
Houlston, Richard S. (författare)
Division of Genetics and Epidemiology, Institute of Cancer Research, London, United Kingdom
Moreno, Victor (författare)
Colorectal Cancer Group, ONCOBELL Program, Bellvitge Biomedical Research Institute, Barcelona, Spain; Consortium for Biomedical Research in Epidemiology and Public Health, Madrid, Spain; Department of Clinical Sciences, Faculty of Medicine, University of Barcelona, Barcelona, Spain; Oncology Data Analytics Program, Catalan Institute of Oncology, Barcelona, Spain
Casey, Graham (författare)
Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, VA, Charlottesville, United States
Peters, Ulrike (författare)
Public Health Sciences Division, Fred Hutchinson Cancer Center, WA, Seattle, United States; Department of Epidemiology, University of Washington, WA, Seattle, United States
Tomlinson, Ian (författare)
Edinburgh Cancer Research Centre, Institute of Genomics and Cancer, University of Edinburgh, Edinburgh, United Kingdom; Institute of Cancer and Genomic Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom
Zheng, Wei (författare)
Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University Medical Center, TN, Nashville, United States
visa färre...
 (creator_code:org_t)
Springer Nature, 2024
2024
Engelska.
Ingår i: Nature Communications. - : Springer Nature. - 2041-1723. ; 15:1
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Genome-wide association studies (GWAS) have identified more than 200 common genetic variants independently associated with colorectal cancer (CRC) risk, but the causal variants and target genes are mostly unknown. We sought to fine-map all known CRC risk loci using GWAS data from 100,204 cases and 154,587 controls of East Asian and European ancestry. Our stepwise conditional analyses revealed 238 independent association signals of CRC risk, each with a set of credible causal variants (CCVs), of which 28 signals had a single CCV. Our cis-eQTL/mQTL and colocalization analyses using colorectal tissue-specific transcriptome and methylome data separately from 1299 and 321 individuals, along with functional genomic investigation, uncovered 136 putative CRC susceptibility genes, including 56 genes not previously reported. Analyses of single-cell RNA-seq data from colorectal tissues revealed 17 putative CRC susceptibility genes with distinct expression patterns in specific cell types. Analyses of whole exome sequencing data provided additional support for several target genes identified in this study as CRC susceptibility genes. Enrichment analyses of the 136 genes uncover pathways not previously linked to CRC risk. Our study substantially expanded association signals for CRC and provided additional insight into the biological mechanisms underlying CRC development.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Medicinsk genetik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Medical Genetics (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

Hitta via bibliotek

Till lärosätets databas

Hitta mer i SwePub

Av författaren/redakt...
Chen, Zhishan
Guo, Xingyi
Tao, Ran
Huyghe, Jeroen R ...
Law, Philip J.
Fernandez-Rozadi ...
visa fler...
Ping, Jie
Jia, Guochong
Long, Jirong
Li, Chao
Shen, Quanhu
Xie, Yuhan
Timofeeva, Maria ...
Thomas, Minta
Schmit, Stephani ...
Díez-Obrero, Vir ...
Devall, Matthew
Moratalla-Navarr ...
Fernandez-Tajes, ...
Palles, Claire
Sherwood, Kitty
Briggs, Sarah E. ...
Svinti, Victoria
Donnelly, Kevin
Farrington, Susa ...
Blackmur, James
Vaughan-Shaw, Pe ...
Shu, Xiao-Ou
Lu, Yingchang
Broderick, Peter
Studd, James
Harrison, Tabith ...
Conti, David V.
Schumacher, Fred ...
Melas, Marilena
Rennert, Gad
Obón-Santacana, ...
Martín-Sánchez, ...
Oh, Jae Hwan
Kim, Jeongseon
Jee, Sun Ha
Jung, Keum Ji
Kweon, Sun-Seog
Shin, Min-Ho
Shin, Aesun
Ahn, Yoon-Ok
Kim, Dong-Hyun
Oze, Isao
Wen, Wanqing
Matsuo, Keitaro
Matsuda, Koichi
Tanikawa, Chizu
Ren, Zefang
Gao, Yu-Tang
Jia, Wei-Hua
Hopper, John L.
Jenkins, Mark A.
Win, Aung Ko
Pai, Rish K.
Figueiredo, Jane ...
Haile, Robert W.
Gallinger, Steve ...
Woods, Michael O ...
Newcomb, Polly A ...
Duggan, David
Cheadle, Jeremy ...
Kaplan, Richard
Kerr, Rachel
Kerr, David
Kirac, Iva
Böhm, Jan
Mecklin, Jukka-P ...
Jousilahti, Pekk ...
Knekt, Paul
Aaltonen, Lauri ...
Rissanen, Harri
Pukkala, Eero
Eriksson, Johan ...
Cajuso, Tatiana
Hänninen, Ulrika
Kondelin, Johann ...
Palin, Kimmo
Tanskanen, Tomas
Renkonen-Sinisal ...
Männistö, Satu
Albanes, Demetri ...
Weinstein, Steph ...
Ruiz-Narvaez, Ed ...
Palmer, Julie R.
Buchanan, Daniel ...
Platz, Elizabeth ...
Visvanathan, Kal ...
Ulrich, Cornelia ...
Siegel, Erin
Brezina, Stefani ...
Gsur, Andrea
Campbell, Peter ...
Chang-Claude, Je ...
Hoffmeister, Mic ...
Brenner, Hermann
Slattery, Martha ...
Potter, John D.
Tsilidis, Kostas ...
Schulze, Matthia ...
Gunter, Marc J.
Murphy, Neil
Castells, Antoni
Castellví-Bel, S ...
Moreira, Leticia
Arndt, Volker
Shcherbina, Anna
Bishop, D. Timot ...
Giles, Graham G.
Southey, Melissa ...
Idos, Gregory E.
McDonnell, Kevin ...
Abu-Ful, Zomorod ...
Greenson, Joel K ...
Shulman, Katerin ...
Lejbkowicz, Flav ...
Offit, Kenneth
Su, Yu-Ru
Steinfelder, Rob ...
Keku, Temitope O ...
van Guelpen, Bet ...
Hudson, Thomas J ...
Hampel, Heather
Pearlman, Rachel
Berndt, Sonja I.
Hayes, Richard B ...
Martinez, Marie ...
Thomas, Sushma S ...
Pharoah, Paul D. ...
Larsson, Susanna ...
Yen, Yun
Lenz, Heinz-Jose ...
White, Emily
Li, Li
Doheny, Kimberly ...
Pugh, Elizabeth
Shelford, Tameka
Chan, Andrew T.
Cruz-Correa, Mar ...
Lindblom, Annika
Hunter, David J.
Joshi, Amit D.
Schafmayer, Clem ...
Scacheri, Peter ...
Kundaje, Anshul
Schoen, Robert E ...
Hampe, Jochen
Stadler, Zsofia ...
Vodicka, Pavel
Vodickova, Ludmi ...
Vymetalkova, Ver ...
Edlund, Christop ...
Gauderman, W. Ja ...
Shibata, David
Toland, Amanda
Markowitz, Sanfo ...
Kim, Andre
Chanock, Stephen ...
van Duijnhoven, ...
Feskens, Edith J ...
Sakoda, Lori C.
Gago-Dominguez, ...
Wolk, Alicja
Pardini, Barbara
FitzGerald, Lies ...
Lee, Soo Chin
Ogino, Shuji
Bien, Stephanie ...
Kooperberg, Char ...
Li, Christopher ...
Lin, Yi
Prentice, Ross
Qu, Conghui
Bézieau, Stéphan ...
Yamaji, Taiki
Sawada, Norie
Iwasaki, Motoki
Le Marchand, Loi ...
Wu, Anna H.
Qu, Chenxu
McNeil, Caroline ...
Coetzee, Gerhard
Hayward, Carolin ...
Deary, Ian J.
Harris, Sarah E.
Theodoratou, Evr ...
Reid, Stuart
Walker, Marion
Ooi, Li Yin
Lau, Ken S.
Zhao, Hongyu
Hsu, Li
Cai, Qiuyin
Dunlop, Malcolm ...
Gruber, Stephen ...
Houlston, Richar ...
Moreno, Victor
Casey, Graham
Peters, Ulrike
Tomlinson, Ian
Zheng, Wei
visa färre...
Om ämnet
MEDICIN OCH HÄLSOVETENSKAP
MEDICIN OCH HÄLS ...
och Medicinska och f ...
och Medicinsk geneti ...
MEDICIN OCH HÄLSOVETENSKAP
MEDICIN OCH HÄLS ...
och Klinisk medicin
och Cancer och onkol ...
Artiklar i publikationen
Nature Communica ...
Av lärosätet
Umeå universitet
Karolinska Institutet

Sök utanför SwePub

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy