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  • Isacson, MDepartment of Clinical Sciences Lund, Pediatrics, Lund University, Lund, Sweden; Sachs' Children and Youth Hospital, Stockholm, Sweden,Neonatology,Sachs’ Children and Youth Hospital,Neonatologi,Sachsska barn- och ungdomssjukhuset,Lund Univ, Dept Clin Sci Lund, Pediat, Lund, Sweden.;SachsChildren & Youth Hosp, Stockholm, Sweden.,Isacson (författare)

Neurobehavioral outcomes at 10 years of age following delayed umbilical cord clamping : a follow-up study after a randomized trial

  • Artikel/kapitelEngelska2025

Förlag, utgivningsår, omfång ...

  • S. Karger,2025
  • electronicrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:umu-244148
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-244148URI
  • https://doi.org/10.1159/000547383DOI
  • https://gup.ub.gu.se/publication/354053URI
  • oai:portal.research.lu.se:publications/01d4b505-780e-4cf3-8010-679119b35d4eURI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-583668URI
  • https://ki.se/en/research/search-research-information?t=2&query=id%3A1129734URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

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  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • © 2025 The Author(s). Published by S. Karger AG, Basel.
  • Introduction: The aim of this study was to explore long-term behavioral consequences of early versus delayed cord clamping (CC) in school-aged children. The hypothesis was that early CC would be associated with an increased risk of symptoms associated with attention deficit hyperactivity disorder (ADHD) due to the lower iron stores following early CC compared with delayed CC.Methods: Exploratory, long-term follow-up study of a randomized controlled trial in Sweden. Full-term, vaginally born, neonates to healthy mothers were originally included and randomized to either early (≤10 s) or delayed (≥180 s) CC. At 10 years of age, scores from the screening questionnaire Swanson, Nolan and Pelham Scale IV (SNAP-IV), that identifies symptoms suggestive of ADHD (but do not diagnose ADHD), were compared between groups of early and delayed CC.Results: We assessed 139/382 (36.4%) children, 64 early CC and 75 delayed CC. No significance in total score and subgroup scores of SNAP-IV was seen when comparing early and delayed CC. In the primary outcome, total scores, mean (standard deviation) of early CC was 14.64 (13.94) and for delayed CC 13.59 (13.41), p = 0.65.Conclusion: Timing of umbilical CC and iron status were not associated with symptoms associated with ADHD in 10-year-old children. Studies with higher follow-up rates and in populations with high prevalence of iron deficiency are needed to verify or discard the findings. Understanding if delayed CC has long-lasting neurobehavioral or neurodevelopmental effects can help develop guidelines and program about neonatal care.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Hellström-Westas, Lena,1954-Uppsala universitet,Perinatal, neonatal och barnkardiologisk forskning(Swepub:uu)lenwe671 (författare)
  • Domellöf, Magnus,1963-Umeå universitet,Pediatrik,Umeå University,Pediat Umeå Univ, Dept Clin Sci, Umeå, Sweden.(Swepub:umu)mado0002 (författare)
  • Dahlgren, Jovanna,1964Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics,University of Gothenburg,Department of Pediatrics, Göteborg Pediatric Growth Research Center (GP-GRC), Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Univ Gothenburg, Sahlgrenska Acad, Göteborg Pediat Growth Res Ctr GP GRC, Dept Pediat, Gothenburg, Sweden.(Swepub:gu)xdajov (författare)
  • Roswall, Josefine,1972Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics,University of Gothenburg,Department of Pediatrics, Göteborg Pediatric Growth Research Center (GP-GRC), Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Region Halland, Halland's Hospital Halmstad, Halmstad, Sweden,Univ Gothenburg, Sahlgrenska Acad, Göteborg Pediat Growth Res Ctr GP GRC, Dept Pediat, Gothenburg, Sweden.;Hallands Hosp Halmstad, Halmstad, Region Halland, Sweden.(Swepub:gu)xanjos (författare)
  • Andersson, OlaDepartment of Clinical Sciences Lund, Pediatrics, Lund University, Lund, Sweden; Department of Neonatology, Skåne University Hospital, Malmö, Sweden,Neonatology,Neonatologi,Lund Univ, Dept Clin Sci Lund, Pediat, Lund, Sweden.;Skane Univ Hosp, Dept Neonatol, Malmö, Sweden.(Swepub:lu)1e77fe69-f227-45cf-991c-dd60f27ab80e (författare)
  • Department of Clinical Sciences Lund, Pediatrics, Lund University, Lund, Sweden; Sachs' Children and Youth Hospital, Stockholm, SwedenNeonatology (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Neonatology: S. Karger122:6, s. 695-7031661-78001661-7819

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