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Sökning: onr:"swepub:oai:DiVA.org:umu-37808" > Symptomatic and fun...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00003604naa a2200421 4500
001oai:DiVA.org:umu-37808
003SwePub
008101115s2006 | |||||||||||000 ||eng|
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-378082 URI
0247 a https://doi.org/10.1016/j.jad.2005.11.0092 DOI
040 a (SwePub)umu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
1001 a Kebede, Derege4 aut
2451 0a Symptomatic and functional outcome of bipolar disorder in Butajira, Ethiopia
264 1b Elsevier BV,c 2006
338 a print2 rdacarrier
520 a BACKGROUND: Limited information is available on the outcome of bipolar disorder in developing countries. OBJECTIVE: To describe the symptomatic and functional outcome of bipolar disorder. METHODS: The psychoses and affective disorder modules of the CIDI were used to screen 68,378 individuals by a door-to-door survey of a defined district in Ethiopia. In addition, key informants were used to identify individuals with probable major mental illnesses. SCAN interviews were completed at the second stage to confirm the diagnosis. A total of 315 cases of bipolar disorder were identified, of which 264 (69 recent-onset and 195 prevalent cases) were prospectively followed for a mean of 2.5 (range 1-4) years by baseline and annual clinical assessments using symptom rating scales. Functional dimensions of the SF-36 scale were used to describe functional outcome. Random coefficient analyses were used to evaluate potential correlates of outcome. RESULTS: The magnitudes of mania and depression symptoms were elevated at baseline but improved with follow-up, although the improvement was less marked for depression. Sociodemographic or clinical variables were not associated with the improvements in symptomatic outcome. Between 35% and 47% of the recent-onset cases had functional role restrictions, while 42-52% of long-standing cases had such restrictions during the follow-up years. Similarly, social and physical functioning deficits were also present in 52-86% and 35-47% of recent-onset and long-standing cases, respectively. The magnitude of depression and mania symptoms was associated with poor functional outcome, while male sex, rural residence and being married were associated with better functional outcome. CONCLUSION: Although there were improvements in function with follow-up, between one-third and one-half of cases continued to have functional deficits.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Psykiatri0 (SwePub)302152 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Psychiatry0 (SwePub)302152 hsv//eng
653 a Bipolar disorder; Outcome; Ethiopia
653 a Psychiatry
653 a Psykiatri
653 a Psychiatry
653 a psykiatri
7001 a Alem, Atalayu Umeå universitet,Psykiatri4 aut
7001 a Shibire, Teshomeu Umeå universitet,Psykiatri4 aut
7001 a Deyassa, Negussieu Umeå universitet,Psykiatri4 aut0 (Swepub:umu)nede0005
7001 a Negash, Alemayehuu Umeå universitet,Psykiatri4 aut
7001 a Beyero, Teferra4 aut
7001 a Medhin, Ghirmay4 aut
7001 a Fekadu, Abebawu Umeå universitet,Psykiatri4 aut
7102 a Umeå universitetb Psykiatri4 org
7730 t Journal of Affective Disordersd : Elsevier BVg 90:2-3, s. 239-249q 90:2-3<239-249x 0165-0327x 1573-2517
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-37808
8564 8u https://doi.org/10.1016/j.jad.2005.11.009

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