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Sökning: onr:"swepub:oai:DiVA.org:uu-369524" > A Risk Assessment o...

A Risk Assessment of Aflatoxin M1 Exposure in Low and Mid-Income Dairy Consumers in Kenya

Ahlberg, Sara (författare)
Int Livestock Res Inst, Dept Biosci, POB 30709, Nairobi 00100, Kenya;Univ Helsinki, Dept Food & Environm Sci, POB 66, FI-00014 Helsinki, Finland
Grace, Delia (författare)
Int Livestock Res Inst, Dept Biosci, POB 30709, Nairobi 00100, Kenya
Kiarie, Gideon (författare)
Mt Kenya Univ, POB 342, Thika 01000, Kenya
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Kirino, Yumi (författare)
Univ Miyazaki, Dept Vet Sci, 1-1 Gakuen Kibanadai Nishi, Miyazaki 8892192, Japan
Lindahl, Johanna (författare)
Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Uppsala universitet,Institutionen för medicinsk biokemi och mikrobiologi,Int Livestock Res Inst, Dept Biosci, POB 30709, Nairobi 00100, Kenya;Swedish Univ Agr Sci, Dept Clin Sci, POB 7054, S-75007 Uppsala, Sweden,Institutionen för kliniska vetenskaper (KV),Department of Clinical Sciences,International Livestock Research Institute (ILRI),Uppsala University
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 (creator_code:org_t)
 
MDPI, 2018
2018
Engelska.
Ingår i: Toxins. - : MDPI. - 2072-6651 .- 2072-6651. ; 10:9
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Aflatoxin M-1 (AFM(1)), a human carcinogen, is found in milk products and may have potentially severe health impacts on milk consumers. We assessed the risk of cancer and stunting as a result of AFM(1) consumption in Nairobi, Kenya, using worst case assumptions of toxicity and data from previous studies. Almost all (99.5%) milk was contaminated with AFM(1). Cancer risk caused by AFM(1) was lower among consumers purchasing from formal markets (0.003 cases per 100,000) than for low-income consumers (0.006 cases per 100,000) purchasing from informal markets. Overall cancer risk (0.004 cases per 100,000) from AFM(1) alone was low. Stunting is multifactorial, but assuming only AFM(1) consumption was the determinant, consumption of milk contaminated with AFM(1) levels found in this study could contribute to 2.1% of children below three years in middle-income families, and 2.4% in low-income families, being stunted. Overall, 2.7% of children could hypothetically be stunted due to AFM(1) exposure from milk. Based on our results AFM(1) levels found in milk could contribute to an average of -0.340 height for age z-score reduction in growth. The exposure to AFM(1) from milk is 46 ng/day on average, but children bear higher exposure of 3.5 ng/kg bodyweight (bw)/day compared to adults, at 0.8 ng/kg bw/day. Our paper shows that concern over aflatoxins in milk in Nairobi is disproportionate if only risk of cancer is considered, but that the effect on stunting children might be much more significant from a public health perspective; however, there is still insufficient data on the health effects of AFM(1).

Ämnesord

AGRICULTURAL SCIENCES  -- Agricultural Science, Forestry and Fisheries -- Food Science (hsv//eng)
LANTBRUKSVETENSKAPER  -- Lantbruksvetenskap, skogsbruk och fiske -- Livsmedelsvetenskap (hsv//swe)
LANTBRUKSVETENSKAPER  -- Lantbruksvetenskap, skogsbruk och fiske (hsv//swe)
AGRICULTURAL SCIENCES  -- Agriculture, Forestry and Fisheries (hsv//eng)
LANTBRUKSVETENSKAPER  -- Veterinärmedicin (hsv//swe)
AGRICULTURAL SCIENCES  -- Veterinary Science (hsv//eng)

Nyckelord

urban consumers
cancer
stunting
milk
dairy products

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