Human polyomaviruses were not detected in cerebrospinal fluid of patients with neurological complications after hematopoietic stem cell transplantation
Gustafsson, Britt (författare)
Department of Clinical Science, Intervention and Technology (CLINTEC),Astrid Lindgren Children‘s Hospital, Karolinska University Hospital-Huddinge, Department of Clinical Science, Intervention & Technology, CLINTEC, Karolinska Institutet, Stockholm, Sweden,Department of Clinical Science, Intervention and Technology (CLINTEC),Department of Clinical Science, Intervention and Technology (CLINTEC)
Priftakis, Peter (författare)
Astrid Lindgren Children‘s Hospital, Karolinska University Hospital-Huddinge, Department of Clinical Science, Intervention & Technology, CLINTEC, Karolinska Institutet, Stockholm, Sweden
Rubin, Johanna (författare)
Department of Clinical Science, Intervention and Technology (CLINTEC),Astrid Lindgren Children‘s Hospital, Karolinska University Hospital-Huddinge, Department of Clinical Science, Intervention & Technology, CLINTEC, Karolinska Institutet, Stockholm, Sweden,Department of Clinical Science, Intervention and Technology (CLINTEC),Department of Clinical Science, Intervention and Technology (CLINTEC)
Uppsala universitet,Neuroonkologi och neurodegeneration,Barnonkologisk klinisk och translationell forskning,Science for Life Laboratory, SciLifeLab,Mälarsjukhuset, Eskilstuna, Sweden;Department of Oncology–Pathology, Karolinska Institutet, Cancer Center Karolinska, Karolinska University Hospital, Stockholm, Sweden
Ramqvist, Torbjörn (författare)
Department of Clinical Science, Intervention and Technology (CLINTEC),Department of Oncology–Pathology, Karolinska Institutet, Cancer Center Karolinska, Karolinska University Hospital, Stockholm, Sweden,Department of Clinical Science, Intervention and Technology (CLINTEC),Department of Clinical Science, Intervention and Technology (CLINTEC)
Dalianis, Tina (författare)
Department of Clinical Science, Intervention and Technology (CLINTEC),Department of Oncology–Pathology, Karolinska Institutet, Cancer Center Karolinska, Karolinska University Hospital, Stockholm, Sweden,Department of Clinical Science, Intervention and Technology (CLINTEC),Department of Clinical Science, Intervention and Technology (CLINTEC)
Gustafsson, B (författare)
Department of Clinical Science, Intervention and Technology (CLINTEC)
Priftakis, P(författare)
Rubin, J (författare)
Department of Clinical Science, Intervention and Technology (CLINTEC)
Giraud, G (författare)
Department of Clinical Science, Intervention and Technology (CLINTEC)
Ramqvist, T (författare)
Department of Clinical Science, Intervention and Technology (CLINTEC)
Dalianis, T (författare)
Department of Clinical Science, Intervention and Technology (CLINTEC)
Background: Neurological complications after allogeneic hematopoietic stem cell transplantation (HSCT) are associated with increased mortality. Reactivation of JC virus, a well-known human polyomavirus (HPyV), can be associated with progressive multifocal leukoencephalopathy after HSCT. Aim: To investigate whether reactivation of the newly discovered HPyVs KIPyV, WUPyV, Merkel cell polyomavirus, HPyV6, HPyV7, trichodysplasia spinulosa polyomavirus, HPyV9 or HPyV10 (MWPyV) is associated with neurological complications after HSCT. Materials & methods: Cerebrospinal fluid from 32 HSCT patients with neurological symptoms was analyzed for the presence of the above HPyVs, including BK virus and JC virus, as well as the primate polyomaviruses lymphotropic polyomavirus and simian virus 40. Results & conclusion: No HPyV DNA was detected or associated with the neurological symptoms the patients showed post-HSCT.
Ämnesord
MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Klinisk laboratoriemedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Clinical Laboratory Medicine (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)