| 1. |
- Lundälv, Jörgen, 1966, et al.
(författare)
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Bättre funktionshinderforskning krävs
- 2011
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Ingår i: Debattartikel i Sundsvalls Tidning den 15 augusti 2011.
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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| 2. |
- Want, Elizabeth J, et al.
(författare)
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From exogenous to endogenous : the inevitable imprint of mass spectrometry in metabolomics.
- 2007
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Ingår i: Journal of Proteome Research. - : American Chemical Society (ACS). - 1535-3893 .- 1535-3907. ; 6:2, s. 459-68
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Tidskriftsartikel (refereegranskat)abstract
- Mass spectrometry (MS) is an established technology in drug metabolite analysis and is now expanding into endogenous metabolite research. Its utility derives from its wide dynamic range, reproducible quantitative analysis, and the ability to analyze biofluids with extreme molecular complexity. The aims of developing mass spectrometry for metabolomics range from understanding basic biochemistry to biomarker discovery and the structural characterization of physiologically important metabolites. In this review, we will discuss the techniques involved in this exciting area and the current and future applications of this field.
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| 3. |
- Wang, Zhenkan, et al.
(författare)
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Transition from HCCI to PPC : Investigation of Fuel Distribution by Planar Laser Induced Fluorescence (PLIF)
- 2017
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Ingår i: SAE International Journal of Engines. - : SAE International. - 1946-3936 .- 1946-3944. ; 10:4
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Tidskriftsartikel (refereegranskat)abstract
- In a previous study, in order to investigate the effect of charge stratification on combustion behavior such as combustion efficiency and combustion phasing which also largely affects the emissions, an experiment was conducted in a heavy-duty compression ignition (CI) metal engine. The engine behavior and emission characteristics were studied in the transition from HCCI mode to PPC mode by varying the start of injection (SOI) timing. To gain more detailed information of the mixing process, in-cylinder laser diagnostic measurements, namely fuel-tracer planar laser induced fluorescence (PLIF) imaging, were conducted in an optical version of the heavy-duty CI engine mentioned above. To the authors’ best knowledge, this is the first time to perform fuel-tracer PLIF measurements in an optical engine with a close to production bowl in piston combustion chamber, under transition conditions from HCCI to PPC mode. Results show that four mixing schemes can be distinguished as the SOI timings are varied during the transition. They are linked to the results presented in the reference paper, where emissions were varied in different zones. For SOI at -100 crank angle degree (CAD), fuel distribution is homogeneous as expected. With other SOI timings, a significant part of the fuel mixture was trapped in the squish region and crevice area before start of combustion (SOC) as shown by PLIF results. The observations in the reference metal engine paper were confirmed by this measurement. Results are also in good agreement with computational fluid dynamics (CFD) simulations performed for this engine.
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| 4. |
- Ingelhammar, Caroline, 1962, et al.
(författare)
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Att avveckla befintliga- och utveckla nya utbildningsprogram utan en kris
- 2015
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Ingår i: 5:e Utvecklingskonferensen för Sveriges ingenjörsutbildningar, Uppsala universitet, 18 – 19 november 2015.
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Konferensbidrag (refereegranskat)abstract
- I höst börjar de första studenterna på de nya omgjorda utbildningarna inom Samhällsbyggnadsteknik på Chalmers. De förändringar som genomförs gäller de första tre åren och de utbildningar som idag benämns Väg-och vatten, Byggingenjör samt Affärsutveckling och Entreprenörskap inom byggsektorn.Vi har idag tre populära program som länge har haft högt söktryck. Förändringen har därför inte skett ur en kris som brukligt är, utan anledningen till förändringen är målet att skapa en mer modern utbildning utgående från examensmålen och med tydligare kopplingar och progressioner mellan kurser i programmen. Den kunskap studenterna får i en kurs ska de utveckla och ha nytta av i andra kurser. En röd tråd ska löpa genom hela utbildningen och studenterna ska förstå helheten och sammanhangenEn stor förändring är att flera kurser kommer att samordnas mellan programmen. Under de första två åren samläser högskoleingenjörsstudenterna och civilingenjörsstudenterna mycket. Det tredje året gör studenterna ett profilval mot en tydlig yrkesinriktning. För de som valt att studera till civilingenjör finns masterprogram som bygger vidare på profilerna. Inriktningarna har delvis tillkommit för att möta och tillgodose byggbranschen önskemål och efterfrågan av ingenjörer.Förnyelse och kvalitetshöjning genom bland annat tydligare koppling mellan utbildningens innehåll och examensmål. Strävan att förbättra utbildningarna genom att utgå från examensmålen till lärandemål, examination och därefter lärandeaktivitet. Processen har varit iterativ där information och workshops riktade till lärare, studenter och avnämare pågått under 5 år.Idag är programstrukturen klar för årskurs 1 och 2, medan arbete fortfarande pågår med strukturen på profilerna i åk 3. I årskurs 1 finns färdiga kursplaner och lärandeaktiviteter som ska genomföras från och med hösten. Parallellt intensifieras arbetet med att fastställa de sista detaljerna i kursplaner för årskurs 2. På detta sätta fortsätter utvecklingsarbetet i de högre årskurserna parallellt med att programmets första år genomförs.
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| 5. |
- Carrizo, Daniel, et al.
(författare)
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Spatial Distributions of DDTs in the Water Masses of the Arctic Ocean
- 2017
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Ingår i: Environmental Science and Technology. - : American Chemical Society (ACS). - 0013-936X .- 1520-5851. ; 51:14, s. 7913-7919
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Tidskriftsartikel (refereegranskat)abstract
- There is a scarcity of data on the amount and distribution of the organochlorine pesticide dichlorodiphenyltrichloroethane (DDT) and its metabolites in intermediate and deep ocean water masses. Here, the distribution and inventories of DDTs in water of the Arctic shelf seas and the interior basin are presented. The occurrence of Sigma 6DDT (0.10-66 pg L-1) in the surface water was dominated by 4,4'-DDE. In the Central Arctic Ocean increasing concentrations of DDE with depth were observed in the Makarov and Amundsen basins. The increasing concentrations down to 2500 m depth is in accordance with previous findings for PCBs and PBDEs. Similar concentrations of DDT and DDEs were found in the surface water, while the relative contribution of DDEs increased with depth, demonstrating a transformation over time and depth. Higher concentrations of DDTs were found in the European part of the Arctic Ocean; these distributions likely reflect a combination of different usage patterns, transport, and fate of these compounds. For instance, the elevated concentrations of DDTs in the Barents and Atlantic sectors of the Arctic Ocean indicate the northbound Atlantic current as a significant conveyor of DDTs. This study contributes to the very rare data on OCPs in the vast deep-water compartments and combined with surface water distribution across the Arctic Ocean helps to improve our understanding of the large-scale fate of DDTs in the Arctic.
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| 6. |
- Odenstedt, Anders
(författare)
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History as Conversation Versus History as Science. Gadamer and Dilthey
- 2011
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Ingår i: Hermeneutics and the Art of Conversation. - Berlin : LIT Verlag. - 9783643111722 ; , s. 481-504
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Bokkapitel (refereegranskat)abstract
- Gadamer holds that Dilthey’s approach to history does not permit a "genuine conversation" (echten Gespräch) with the claims of the past. A genuine conversation, Gadamer holds, is such that its subject matter (Sache) is stressed. Although trust normally prevails in cases of this kind, one may of course come to doubt the claims of the other. But doubt is then expressed in critique, i.e., in claims to the effect that the other has failed to describe the subject matter properly. What Dilthey does, Gadamer holds, is something different. Dilthey neither affirms nor denies the claims of the past in treating them as a collection of historical sources. According to Gadamer, this approach fails to respect the “moral bond” (sittliche Verbindlichkeit) as it occurs in, e.g., everyday conversation. Respecting this bond means treating claims as true or false and not as mere expressions of the speaker or of his historical context. In this paper, the validity of Gadamer's views on everyday conversation in general and on Dilthey in particular is discussed.
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| 7. |
- Tasin, Marco
(författare)
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Spotting the invaders: A monitoring system based on plant volatiles to forecast apple fruit moth attacks in apple orchards
- 2015
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Ingår i: Basic and Applied Ecology. - : Elsevier BV. - 1439-1791 .- 1618-0089. ; 16, s. 354-364
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Tidskriftsartikel (refereegranskat)abstract
- The exploitation of cues mediating insect-plant interactions with a view to enhance sustainable management of agroecosystems is an exciting and emergent area. Practical applications are, however, limited due to discrepancies between attraction of insects to lures in the laboratory and in the field. We hypothesised that the background odour of the crop along with the modality of release of volatiles in the field could play a role in filling the gap. Our study system comprised the apple fruit moth Argyresthia conjugella, its native host, rowan, Sorbus aucuparia, and the recurrently colonised secondary host apple, Malus communis. The attractiveness of several sources, including host plants, their collected headspaces and synthetic mimics, was measured both in the laboratory and in the field. In orchards, apple fruit moth females and males were caught in traps baited with rowan clusters. In the wind tunnel, attraction was observed when rowan (either as plant or headspace) was used as stimulus. The background from apple did not affect the attraction to the rowan odour. Whilst the response to a two-component rowan mimic decreased in the presence of an apple background, a seven-component mimic remained effective in such a background. In rowan intermast years, traps baited with this blend caught consistent numbers of moths during their migration to apple. Long lasting dispensing devices with a controlled release over the entire period of pest migration allowed a much more consistent catch of moths compared to a standard device. Results indicate that knowledge of the volatile background of the crop and of the optimisation of the dispensing device is essential when moving attractants from the laboratory or semi-laboratory environment out into the field. By considering these factors, we developed a plant volatile-based attractant to monitor the apple fruit moth and use insecticides only where and when needed. Our concept can be extended to other insect-plant interactions.
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| 8. |
- Isotalo, A. E., et al.
(författare)
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Preventing xenon oscillations in Monte Carlo burnup calculations by enforcing equilibrium xenon distribution
- 2013
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Ingår i: Annals of Nuclear Energy. - : Elsevier BV. - 0306-4549 .- 1873-2100. ; 60, s. 78-85
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Tidskriftsartikel (refereegranskat)abstract
- Existing Monte Carlo burnup codes suffer from instabilities caused by spatial xenon oscillations. These oscillations can be prevented by forcing equilibrium between the neutron flux and saturated xenon distribution. The equilibrium calculation can be integrated to Monte Carlo neutronics, which provides a simple and lightweight solution that can be used with any of the existing burnup calculation algorithms. The stabilizing effect of this approach, as well as its limitations are demonstrated using the reactor physics code Serpent.
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| 9. |
- Larsson, Charlotte A, et al.
(författare)
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Clusters of AMI risk factors and their association with left ventricular hypertrophy: A population-based study within the Skaraborg Project, Sweden.
- 2013
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Ingår i: International Journal of Cardiology. - : Elsevier BV. - 0167-5273. ; 168:6, s. 5416-5421
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVES: Risk factors for acute myocardial infarction (AMI) are known to cluster and to be differently distributed in men and women. The aim of this study was to sex-specifically explore clusters of acknowledged AMI risk factors by factor analysis, and to study whether such clusters are associated with left ventricular hypertrophy (LVH), used as a subclinical measure of CHD. METHODS: In 2001-2005, 2328 subjects (30-74years) were randomly selected from two municipalities in Sweden (participation-rate 76%) and were assessed with regard to cardiovascular risk factors; 852 participants also had an echocardiographic examination performed. RESULTS: Factor analysis identified three identical factors in men and women. WHR, HOMA-ir, systolic blood pressure, and ApoB/ApoA1 loaded significantly on the principal "metabolic factor", leisure-time physical activity and self-rated health loaded significantly on the "vitality factor", and smoking and alcohol consumption loaded significantly on the "addiction factor". The metabolic factor was associated with LVH in both men (P<0.001) and women (P<0.001), whereas the addiction factor was associated with LVH solely in men (P=0.002). CONCLUSIONS: The consistent pattern in the clustering of acknowledged AMI risk factors suggests common underlying mechanisms in both men and women. However, whereas the metabolic factor was paramount in both men and women in the association with LVH, the addiction factor had an impact solely in men. As LVH often precedes AMI, a deeper understanding of risk factors for LVH, including consideration of the supposed sex differences, can be useful in order to explore prevention strategies for AMI. © 2013.
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