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High prevalence of ...
High prevalence of hospital-acquired infections caused by gram-negative carbapenem resistant strains in Vietnamese pediatric ICUs A multi-centre point prevalence survey
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Le, Ngai Kien (författare)
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Wertheim, HF (författare)
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Vu, Phu Dinh (författare)
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Khu, Dung Thi Khanh (författare)
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Le, Hai Tanh (författare)
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Hoang, Bich Thi Ngoc (författare)
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Vo, Vu Thanh (författare)
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Lam, YM (författare)
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Vu, DTV (författare)
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Nguyen, TH (författare)
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Thai, TQ (författare)
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Nilsson, Lennart E (författare)
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Rydell, Ulf (författare)
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Van Nguyen, K (författare)
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Nadjm, Behzad (författare)
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Clarkson, Louise (författare)
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Hanberger, Håkan (författare)
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Larsson, Mattias (författare)
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- LIPPINCOTT WILLIAMS & WILKINS 2016
- 2016
- Engelska.
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Ingår i: Medicine (Baltimore, Md.). - 0025-7974. ; 95:27
Abstract
Ämnesord
Stäng
- There is scarce information regarding hospital-acquired infections (HAIs) among children in resource-constrained settings. This study aims to measure prevalence of HAIs in Vietnamese pediatric hospitals. Monthly point prevalence surveys (PPSs) in 6 pediatric intensive care units (ICUs) in 3 referral hospitals during 1 year. A total of 1363 cases (1143 children) were surveyed, 59.9% male, average age 11 months. Admission sources were: other hospital 49.3%, current hospital 36.5%, and community 15.3%. Reasons for admission were: infectious disease (66%), noninfectious (20.8%), and surgery/trauma (11.3%). Intubation rate was 47.8%, central venous catheter 29.4%, peripheral venous catheter 86.2%, urinary catheter 14.6%, and hemodialysis/filtration 1.7%. HAI was diagnosed in 33.1% of the cases: pneumonia (52.2%), septicemia (26.4%), surgical site infection (2%), and necrotizing enterocolitis (2%). Significant risk factors for HAI included age under 7 months, intubation and infection at admission. Microbiological findings were reported in 212 cases (43%) with 276 isolates: 50 Klebsiella pneumoniae, 46 Pseudomonas aeruginosa, and 39 Acinetobacter baumannii, with carbapenem resistance detected in 55%, 71%, and 65%, respectively. Staphylococcus aureus was cultured in 18 cases, with 81% methicillin-resistant Staphylococcus aureus. Most children (87.6%) received antibiotics, with an average of 1.6 antibiotics per case. Colistin was administered to 96 patients, 93% with HAI and 49% with culture confirmed carbapenem resistance. The high prevalence of HAI with carbapenem resistant gram-negative strains and common treatment with broad-spectrum antibiotics and colistin suggests that interventions are needed to prevent HAI and to optimize antibiotic use.
Ämnesord
- Medical and Health Sciences (hsv)
- Clinical Medicine (hsv)
- Family Medicine (hsv)
- Medicin och hälsovetenskap (hsv)
- Klinisk medicin (hsv)
- Allmän medicin (hsv)
Nyckelord
- hospital-acquired infections; ICU; pediatric; Vietnam
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Till lärosätets databas
- Av författaren/redakt...
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Le, Ngai Kien
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Wertheim, HF
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Vu, Phu Dinh
-
Khu, Dung Thi Kh ...
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Le, Hai Tanh
-
Hoang, Bich Thi ...
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visa fler...
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Vo, Vu Thanh
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Lam, YM
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Vu, DTV
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Nguyen, TH
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Thai, TQ
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Nilsson, Lennart ...
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Rydell, Ulf
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Van Nguyen, K
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Nadjm, Behzad
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Clarkson, Louise
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Hanberger, Håkan
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Larsson, Mattias
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visa färre...
- Av lärosätet
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