| 1. |
- Håkansson, Bo, et al.
(författare)
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A novel bone conduction implant (BCI)
- 2009
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Ingår i: 2<sup>nd</sup> Int Symposium on Bone Conduction Hearing – Craniofacial Osseointegration, Göteborg, Sweden.
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Konferensbidrag (refereegranskat)
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| 2. |
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| 3. |
- Håkansson, Bo, 1953, et al.
(författare)
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Percutaneous Versus Transcutaneous Bone Conduction Implant System : A Feasibility Study on a Cadaver Head
- 2008
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Ingår i: Otology and Neurotology. - 1531-7129 .- 1537-4505. ; 29:8, s. 1132-1139
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Tidskriftsartikel (refereegranskat)abstract
- Objective: Percutaneous bone-anchored hearing aid (BAHA) is an important rehabilitation alternative for patients who have conductive or mixed hearing loss. However, these devices use a percutaneous and bone-anchored implant that has some drawbacks reported. A transcutaneous bone conduction implant system (BCI) is proposed as an alternative to the percutaneous system because it leaves the skin intact. The BCI transmits the signal to a permanently implanted transducer with an induction loop system through the intact skin. The aim of this study was to compare the electroacoustic performance of the BAHA Classic-300 with a full-scale BCI on a cadaver head in a sound field. The BCI comprised the audio processor of the vibrant sound bridge connected to a balanced vibration transducer (balanced electromagnetic separation transducer).Methods: Implants with snap abutments were placed in the parietal bone (Classic-300) and 15-mm deep in the temporal bone (BCI). The vibration responses at the ipsilateral and contralateral cochlear promontories were measured with a laser Doppler vibrometer, with the beam aimed through the ear canal.Results: Results show that the BCI produces approximately 5 dB higher maximum output level and has a slightly lower distortion than the Classic-300 at the ipsilateral promontorium at speech frequencies. At the contralateral promontorium, the maximum output level was considerably lower for the BCI than for the Classic-300 except in the 1-2 kHz range, where it was similar.Conclusion: Present results support the proposal that a BCI system can be a realistic alternative to a BAHA.
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| 4. |
- Håkansson, Katarina, et al.
(författare)
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Degradation of acetonitrile through a sequence of microbial processes
- 2005
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Ingår i: Water Research. - 0043-1354 .- 1879-2448. ; , s. 648-654-
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Tidskriftsartikel (refereegranskat)abstract
- Degradation of nitrogen containing organic compounds often leads to formation of ammonium and low molecular weight organic compounds. The study is focuseed on degradtion of acetonitrile in a sequence of stirred biofilm reactors, where degradation of acetonitrile to acetic acid and ammonia takes place in the first two reactors. A large fraction of the acetic acid is also degraded in these reactors. The subsequent two reactors were introduced in order to take care of the ammonia, while a fifth reactor was a polishing step before the water was released to the recipient. From earlier studies it is known that the rate of acetonitrile degradation is approximately 80 g acetonitrile/(m3 reactor h). This means that the reactors involved in remval of the nitrogen component needs to be far larger than those dealing with degradation of the more complex molecules.
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| 5. |
- Håkansson, Kristina, et al.
(författare)
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Degradation of acetonitrile through a sequence of microbial reactors
- 2005
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Ingår i: Water Research. - : Elsevier BV. - 1879-2448 .- 0043-1354. ; 39:4, s. 648-654
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Tidskriftsartikel (refereegranskat)abstract
- Degradation of nitrogen containing organic compounds often leads to formation of ammonium and some low molecular weight organic compounds. The study is focused on degradation of acetonitrile in a sequence of stirred biofilm reactors, where the degradation of acetonitrile into acetic acid and ammonia takes place in the first two reactors. A large fraction of the acetic acid is also degraded in these reactors. The subsequent two reactors were introduced in order to take care of the ammonia, while a fifth reactor was a polishing step before the water was released to the recipient. From earlier studies it is known that the rate of acetonitrile degradation is approximately 80 g acetonitrile/(m(3) reactor h). In the present study nitrification proceeded with 10g NH4+-N/(m(3) reactor h) and the denitrification by 35g NOx--N/ (m(3) reactor h). This means that the reactors involved in removal of the nitrogen component needs to be far larger than those dealing with degradation of the more complex molecules. (C) 2004 Elsevier Ltd. All rights reserved.
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| 6. |
- Håkansson, Stellan, et al.
(författare)
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Group B streptococcal carriage in Sweden : a national study on risk factors for mother and infant colonisation
- 2008
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Ingår i: Acta Obstetricia et Gynecologica Scandinavica. - Stockholm : Wiley. - 0001-6349 .- 1600-0412. ; 87:1, s. 50-58
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Tidskriftsartikel (refereegranskat)abstract
- Background. To study group B streptococcus (GBS) colonisation in parturients and infants in relation to obstetric outcome and to define serotypes and antibiotic resistance in GBS isolates acquired. Methods. A population-based, national cohort of parturients and their infants was investigated. During 1 calendar week in 2005 all women giving birth (n=1,754) were requested to participate in the study. Results. A total of 1,569 mother/infant pairs with obstetric and bacteriological data were obtained. Maternal carriage rate was 25.4% (95% confidence interval (CI): 23.3-27.6). In GBS-positive mothers with vaginal delivery and no intrapartum antibiotics, the infant colonisation rate was 68%. Some 30% of infants were colonised after acute caesarean section, and 0% were colonised after an elective procedure. Duration of transport of maternal recto/vaginal swabs of more than 1 day impeded culture sensitivity. Infant mMales were more frequently colonised than females (76.9 versus 59.8%, odds ratio (OR): 2.16; 95% CI: 1.27-3.70), as were infants born after rupture of membranes ≥24 h (p =0.039). Gestational age, birth weight and duration of labor did not significantly influence infant colonisation. Some 30% of parturients with at least one risk factor for neonatal disease received intrapartum antibiotics. The most common GBS serotypes were type III and V. Some 5% of the isolates were resistant to clindamycin and erythromycin, respectively. Conclusions. Maternal GBS prevalence and infant transfer rate were high in Sweden. Males were more frequently colonised than females. The sensitivity of maternal cultures decreased with the duration of sample transport. Clindamycin resistance was scarce. The use of intrapartum antibiotics was limited in parturients with obstetric risk factors for early onset group B streptococcal disease.
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| 7. |
- Håkansson, Torbjörn, et al.
(författare)
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Sulphate reducing bacteria to precipitate mercury after electrokinetic soil remediation
- 2008
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Ingår i: International journal of environmental science and technology. - 1735-1472 .- 1735-2630. ; 5:2, s. 267-274
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Tidskriftsartikel (refereegranskat)abstract
- Combined treatment with electroremediation and sulphate reducing bacteria (SRB) was tested in laboratory and pilot scale. The contaminated soil came from a chlor-alkali factory and contained about 100 mg/kg Hg. Iodide/iodine complexing agent was used to mobilize mercury. Mercury iodide complexes were moved to the anode solution using an electric field. The anode solution was then mixed with hydrogen sulphide (H2S) containing water, causing precipitation of mercury sulphide. The H2S was produced at site by a SRB reactor. Precipitation problems arising from the nature of the anode solution were expected, since this solution is highly acidic, very oxidised and may contain iodide/iodine that strongly complexes mercury and can hinder mercury sulphide precipitation. Mercury concentrations in the anode solution were up to 65.7 mg/L (field) and 15.4 mg/L (lab. scale). Reduction of mercury in the water was >93% at all times. Iodide did not hinder the process: Nonetheless, in the lab system, iodide concentration was high in the anode solution but mercury reduction was > 99.9%. The redox potential was sufficiently low for HgS precipitation during the experiments, except for a short period, when the mercury removal decreased to 94%. Sulphate reducing bacteria are shown as a viable tool for the treatment of mercury contaminated, acidic, oxidative, iodide containing water, such as that produced by electrokinetic remediation. A second SRB step or other water treatment is required to reduce the mercury concentration to environmentally acceptable levels. Redox. potential is the most sensitive factor in the system.
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| 8. |
- Lindberg, Bo, et al.
(författare)
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Modeling of Cherenkov light emission from BWR nuclear fuel with missing or substituted rods
- 2006
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Ingår i: IAEA Symposium on International Safeguards: Addressing Verification Challenges.
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Konferensbidrag (populärvet., debatt m.m.)abstract
- Computer simulations of Cherenkov glow from spent nuclear fuel were carried out. Spent nuclear fuel in storage ponds are verified with the help of the Cherenkov viewing device (CVD) and the Digital Cherenkov viewing device (DCVD). The instruments image the Cherenkov glow generated by gamma ray emissions from spent fuel into the water. An attempt to build a realistic digital model of the DCVD image containing partial-length, missing, and substituted rods was made to see if the effects of the deviations from normal can be predicted. It was concluded that partial-length or missing rods in the model was in good agreement with measured data, but replaced rods in the model showed a weaker attenuation of the Cherenkov glow than the observed DCVD images.
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| 9. |
- Håkansson, Anna, 1978, et al.
(författare)
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Cyclooxygenase-2 polymorphisms in Parkinson's disease.
- 2007
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Ingår i: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. - : Wiley. - 1552-4841. ; 144:3, s. 367-9
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Tidskriftsartikel (refereegranskat)abstract
- Accumulating evidence indicate that cyclooxygenase-2 (COX-2) is of pathophysiological importance for the neurodegeneration in Parkinson's disease (PD). For example, in a large epidemiological study, use of NSAIDs was associated with a lower risk of PD. Genetic variants of the COX-2 gene might therefore influence the risk of developing the disease. The genotype distribution of four common single nucleotide polymorphisms (SNPs) in the COX-2 gene (rs689466:A496G, rs20417:G926C, rs5277:G3050C, rs5275:C8473T) was analyzed in PD patients and control subjects in a Swedish population. No differences could be seen between the PD-patient and controls regarding the A496G, G926C, and G3050C SNPs, but the allele frequency of the C8473T SNP was found to differ when male patients were compared to controls (P = 0.007). In females no difference could be seen between PD-patients and controls. In conclusion, the results suggest a possible influence of the COX-2 C8473T SNP in PD, although it only seems to be of importance in men.
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| 10. |
- Håkansson, Anna, 1978, et al.
(författare)
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Investigation of genes coding for inflammatory components in Parkinson's disease.
- 2005
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Ingår i: Movement disorders : official journal of the Movement Disorder Society. - : Wiley. - 0885-3185 .- 1531-8257. ; 20:5, s. 569-73
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Tidskriftsartikel (refereegranskat)abstract
- Several findings obtained recently indicate that inflammation may contribute to the pathogenesis in Parkinson's disease (PD). Genetic variants of genes coding for components involved in immune reactions in the brain might therefore influence the risk of developing PD or the age of disease onset. Five single nucleotide polymorphisms (SNPs) in the genes coding for interferon-gamma (IFN-gamma; T874A in intron 1), interferon-gamma receptor 2 (IFN-gamma R2; Gln64Arg), interleukin-10 (IL-10; G1082A in the promoter region), platelet-activating factor acetylhydrolase (PAF-AH; Val379Ala), and intercellular adhesion molecule 1 (ICAM-1; Lys469Glu) were genotyped, using pyrosequencing, in 265 patients with PD and 308 controls. None of the investigated SNPs was found to be associated with PD; however, the G1082A polymorphism in the IL-10 gene promoter was found to be related to the age of disease onset. Linear regression showed a significantly earlier onset with more A-alleles (P = 0.0095; after Bonferroni correction, P = 0.048), resulting in a 5-year delayed age of onset of the disease for individuals having two G-alleles compared with individuals having two A-alleles. The results indicate that the IL-10 G1082A SNP could possibly be related to the age of onset of PD.
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