| 1. |
- Maret-Ouda, John, et al.
(författare)
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The risk of mortality following secondary fundoplication in a population-based cohort study
- 2016
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Ingår i: The American Journal of Surgery. - Stockholm : Karolinska Institutet, Dept of Molecular Medicine and Surgery. - 0002-9610 .- 1879-1883.
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Mortality following laparoscopic fundoplication has been found to be negligible. However, some patients require secondary fundoplication, and the risk of mortality following such procedure is scarcely studied. METHODS: This nationwide Swedish population-based cohort study included all patients undergoing secondary fundoplication following primary laparoscopic fundoplication in 1997 to 2013, regardless of indication. Primary outcome was mortality within 90 days of surgery, and secondary outcome was postoperative length of hospital stay. RESULTS: A total of 9,765 patients underwent primary laparoscopic fundoplication, 540 (5.5%) patients underwent secondary fundoplication. About 382 (70.7%) were conducted laparoscopically, and 158 (29.3%) were conducted with an open technique. No deaths occurred within 90 days of the secondary fundoplication. Median length of stay was longer following secondary fundoplication (4.8 days, interquartile range 1.0 to 5.0 days), compared to primary laparoscopic fundoplication (2.5 days, interquartile range 1.0 to 3.0 days). CONCLUSIONS: This population-based cohort study indicates that secondary fundoplication following primary laparoscopic fundoplication is a safe procedure. The longer hospital stay following secondary fundoplication compared to primary laparoscopic fundoplication is likely explained by the higher rate of open surgical approach.
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| 2. |
- Arnbjörnsson, Einar
(författare)
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A neuromuscular basis for the development of right inguinal hernia after appendectomy
- 1982
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Ingår i: The American Journal of Surgery. - : Elsevier BV. - 0002-9610. ; 143:3, s. 367-369
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Tidskriftsartikel (refereegranskat)abstract
- Abdominal muscular contractions may have a protective influence against the development of indirect inguinal hernia. A portion of the transversus abdominus muscles acts on the internal inguinal rings and produces a closure mechanism during voluntary abdominal muscular activity. It follows, therefore, that injury or inactivation of this mechanism may be an etiologic factor in the development of indirect inguinal hernia. One cause of injury to this mechanism is denervation and regional muscle paralysis occurring during a surgical procedure. Electromyographic findings support the hypothesis that paralysis of inferior fibers of the transversus abdominus muscle occurred after appendectomy, and may have been important in the development of an inguinal hernia.
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| 3. |
- Arnbjörnsson, Einar, et al.
(författare)
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Changes in hospital costs for an appendectomy : 1955, 1965, and 1975
- 1983
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Ingår i: The American Journal of Surgery. - : Elsevier BV. - 0002-9610. ; 146:3, s. 342-345
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Tidskriftsartikel (refereegranskat)abstract
- A reduction in the number of postoperative bed days for patients who underwent appendectomy led to a study of changes in hospital costs of appendectomies for the years 1955, and 1965, and 1975. No significant changes were found in the total hospital costs. However, the postoperative costs decreased by 36 percent from 1955 to 1975 due to a decrease in the mean duration of hospital stay. During the same period of time, the perioperative costs increased by 90 percent due to increased length of operation time correlated with an increasing proportion of inexperienced operating surgeons. At present, there seem to be few possible ways to increase the cost efficiency of treating appendicitis.
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| 4. |
- Arnbjörnsson, Einar
(författare)
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Development of right inguinal hernia after appendectomy
- 1982
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Ingår i: The American Journal of Surgery. - : Elsevier BV. - 0002-9610. ; 143:1, s. 174-175
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Tidskriftsartikel (refereegranskat)abstract
- The incidence of right inguinal hernia is significantly greater in patients who have undergone appendectomy than in the general population. The most likely cause of such hernias is injury to the segmental nerve supply to the inguinal musculature. The choice of incision at appendectomy may therefore be important, and the surgeon should avoid injury to the nerve branches and important structures in the inguinal region, especially below the horizontal line extending from the anterosuperior iliac spine to the rectus muscle.
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| 5. |
- Arnbjörnsson, Einar, et al.
(författare)
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Role of obstruction in the pathogenesis of acute appendicitis
- 1984
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Ingår i: The American Journal of Surgery. - : Elsevier BV. - 1879-1883 .- 0002-9610. ; 147:3, s. 390-392
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Tidskriftsartikel (refereegranskat)abstract
- The role of obstruction in the pathogenesis of acute appendicitis was studied by measuring the pressure in the appendix perioperatively in 24 patients operated on with an appendectomy because of suspected acute appendicitis. The technique used involved inserting a fine needle through the apex into the appendix lumen and measuring the hydrostatic pressure required to inject saline solution. In three patients with a gangrenous appendix found at operation, and in two patients with a phlegmonous appendix, there were signs of obstruction of the appendix lumen as revealed by increased pressure within it. In 14 patients with a phlegmonous appendix found at operation, no signs of obstruction were found. These experimental data suggest that obstruction is not an important causative agent of acute appendicitis, but might develop as a result of the inflammatory process.
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| 6. |
- Thörne, Johan, et al.
(författare)
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Early posttraumatic pulmonary platelet trapping and its potentiation by oral pretreatment with alcohol
- 1986
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Ingår i: The American Journal of Surgery. - : Elsevier BV. - 1879-1883 .- 0002-9610. ; 151:2, s. 216-220
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Tidskriftsartikel (refereegranskat)abstract
- Soft tissue trauma is associated with platelet aggregation and sequestration in the lungs. This is believed to be an early step in the later development of adult respiratory distress syndrome. In the present experiment using a new method for in vivo dynamic studies of platelet sequestration, we wanted to evaluate the effect of soft tissue trauma on pulmonary platelet trapping in pigs and the influence of acute alcohol intoxication. The results show that significant pulmonary platelet trapping is registered within minutes of trauma and that alcohol significantly increases platelet sequestration in the lungs. This indicates an increased risk for posttraumatic pulmonary problems in alcohol-intoxicated trauma victims
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| 7. |
- Ahlman, Håkan, 1947, et al.
(författare)
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Neuroendocrine insights from the laboratory to the clinic.
- 1996
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Ingår i: American journal of surgery. - 0002-9610. ; 172:1, s. 61-7
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Tidskriftsartikel (refereegranskat)abstract
- The interaction between adrenergic nerves and enterochromaffin (EC) cells was studied in health and disease using animal models and patients with the midgut carcinoid syndrome.
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| 8. |
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| 9. |
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| 10. |
- Trulsson, Lena, 1950-, et al.
(författare)
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Telomerase activity in surgical specimens and fine-needle aspiration biopsies from hyperplastic and neoplastic human thyroid tissues
- 2003
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Ingår i: American Journal of Surgery. - 0002-9610 .- 1879-1883. ; 186:1, s. 83-88
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Tidskriftsartikel (refereegranskat)abstract
- Background: Telomerase activity (TA) indicates malignancy, but activated lymphocytes also express TA. Correlation between TA in thyroid tissues and fine-needle aspiration (FNA) samples and knowledge about TA in adjacent tissue are of importance. Methods: The telomeric repeat amplification protocol assay followed by enzyme-linked immunosorbent assay detection was performed on 78 thyroid cases including 53 suspected malignancies, preoperative and perioperative FNA specimens, and adjacent tissue. Results: Benign lesions in cancer-suspected cases were TA negative. Eight of 13 papillary (62%) and 4 of 5 follicular (80%) tumors were TA positive (TA+). Lower TA was observed in conventional papillary cancer than in follicular, tall cell variant of papillary and anaplastic cancers. Adjacent tissues with lymphocyte infiltration were TA+ in 9 of 17 cases (53%). Nine of 65 adjacent tissues (14%) were TA+. Three of 6 preoperative and 9 of 11 perioperative FNA samples from malignant tumors corresponded to the tissue TA. Conclusions: High TA may reflect more severe thyroid cancer. Telomerase activity in FNA biopsies does not add reliable diagnostic information, and presence of lymphocytes can give false-positive results.
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