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- Lönngren, Vincent, 1977-, et al.
(författare)
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Neutrophilic and Eosinophilic Dermatitis Caused by Contact Allergic Reaction to Paraphenylenediamine in Hair Dye
- 2012
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Ingår i: Archives of Dermatology. - : American Medical Association (AMA). - 0003-987X .- 1538-3652. ; 148:11, s. 1299-1301
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Tidskriftsartikel (refereegranskat)abstract
- Background: Paraphenylenediamine (PPD) in hair dyes can cause systemic as well as cutaneous allergic reactions such as neutrophilic and eosinophilic dermatitis. The symptoms are often severe. The acute lesion is normally histologically indistinguishable from any eczematous reaction with marked spongiosis. Observations: We report a case of allergic contact dermatitis caused by the use of hair dye containing PPD that developed in a patient who had been using the same hair dye for many years. Her symptoms included scalp dermatitis and widespread skin lesions as well as lymphadenopathy and quite possibly dyspnea resembling asthma. What is most remarkable about this case is the histopathologic finding of neutrophilic cellulitis and a marked neutrophilic infiltrate with variable spongiosis. This unique finding was confirmed by histologic analysis of a patch test lesion specimen. Conclusion: It is always important to consider contact allergic dermatitis as a cause of dermatitis because of the variable presentation of the disease, including unique histologic findings that do not fit the conventional picture, as in the present case. Arch Dermatol. 2012;148(11):1299-1301
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- Menzies, Scott W, et al.
(författare)
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Dermoscopic evaluation of amelanotic and hypomelanotic melanoma.
- 2008
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Ingår i: Archives of dermatology. - : American Medical Association (AMA). - 1538-3652 .- 0003-987X. ; 144:9, s. 1120-7
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Tidskriftsartikel (refereegranskat)abstract
- To determine the predictive dermoscopic features of amelanotic and hypomelanotic melanoma.
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- Cordain, L, et al.
(författare)
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Acne vulgaris - A disease of western civilization
- 2002
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Ingår i: Archives of Dermatology. - : American Medical Association (AMA). - 0003-987X. ; 138:12, s. 1584-1590
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Tidskriftsartikel (refereegranskat)abstract
- Background: In westernized societies, acne vulgaris is a nearly universal skin disease afflicting 79% to 95% of the adolescent population. In men and women older than 25 years, 40% to 54% have some degree of facial acne, and clinical facial acne persists into middle age in 12% of women and 3% of men. Epidemiological evidence suggests that acne incidence rates are considerably lower in nonwesternized societies. Herein we report the prevalence of acne in 2 nonwesternized populations: the Kitavan Islanders of Papua New Guinea and the Ache hunter-gatherers of Paraguay. Additionally, we analyze how elements in nonwesternized environments may influence the development of acne. Observations: Of 1200 Kitavan subjects examined (including 300 aged 15-25 years), no case of acne (grade I with multiple comedones or grades 2-4) was observed. Of 115 Ache subjects examined (including 15 aged 15-25 years) over 843 days, no case of active acne (grades 1-4) was observed. Conclusions: The astonishing difference in acne incidence rates between nonwesternized and fully modernized societies cannot be solely attributed to genetic differences among populations but likely results from differing environmental factors. identification of these factors may be useful in the treatment of acne in Western populations.
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