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- Andersson, Ola, et al.
(författare)
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Cord Management of the Term Newborn
- 2021
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Ingår i: Clinics in Perinatology. - : Elsevier BV. - 0095-5108. ; 48:3, s. 447-470
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Forskningsöversikt (refereegranskat)abstract
- Keeping the umbilical cord intact after delivery facilitates transition from fetal to neonatal circulation and allows a placental transfusion of a considerable amount of blood. A delay of at least 3 minutes improves neurodevelopmental outcomes in term infants. Although regarded as common sense and practiced by many midwives, implementation of delayed cord clamping into practice has been unduly slow, partly because of beliefs regarding theoretic risks of jaundice and lack of understanding regarding the long-term benefits. This article provides arguments for delaying cord clamping for a minimum of 3 minutes.
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- Fleiss, Bobbi, et al.
(författare)
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Stem Cell Therapy for Neonatal Brain Injury.
- 2014
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Ingår i: Clinics in perinatology. - : Elsevier BV. - 1557-9840 .- 0095-5108. ; 41:1, s. 133-148
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Tidskriftsartikel (refereegranskat)abstract
- This article introduces the basic concepts of modeling neonatal brain injury and provides background information regarding each of the commonly used types of stem cells. It summarizes the findings of preclinical research testing the therapeutic potential of stem cells in animal models of neonatal brain injury, reports briefly on the status of clinical trials, and discusses the important ongoing issues that need to be addressed before stem cell therapy is used to repair the injured brain.
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- Holmström, Gerd, et al.
(författare)
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Outcome of Retinopathy of Prematurity
- 2013
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Ingår i: Clinics of Perinatology. - : Elsevier BV. - 0095-5108 .- 1557-9840. ; 40:2, s. 311-321
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Tidskriftsartikel (refereegranskat)abstract
- In prematurely born children, various visual and ophthalmologic sequelae occur because of both retinopathy of prematurity (ROP) and preterm birth per se. Several long-term follow-up studies have described the outcome of ROP. Visual impairment and blindness are well-known consequences, but the prevalence varies globally because of differing neonatal and ophthalmologic care. Improving treatment options and criteria for the treatment of ROP are continuously changing the ophthalmologic outcome. The anatomic outcome has improved with treatment, but good anatomic outcome in treated severe ROP does not always reflect the functional outcome. There is no consensus regarding long-term follow-up of prematurely born children.
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- Smith, L. E., et al.
(författare)
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The Biology of Retinopathy of Prematurity How Knowledge of Pathogenesis Guides Treatment
- 2013
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Ingår i: Clinics in Perinatology. - : Elsevier BV. - 0095-5108. ; 40:2, s. 201-214
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Tidskriftsartikel (refereegranskat)abstract
- Retinopathy of prematurity occurs because the retina of a preterm infant at birth is incompletely vascularized, and if the postnatal environment does not match the in utero environment that supported retinal development, the vessels and neural retina will not grow normally. Risk factors determined from many clinical studies and animal studies fall into 2 categories: prenatal factors and postnatal factors.
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