| 1. |
- Hammes, T. O., et al.
(författare)
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Lactobacillus rhamnosus GG reduces hepatic fibrosis in a model of chronic liver disease in rats
- 2017
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Ingår i: Nutricion Hospitalaria. - : ARAN Ediciones. - 0212-1611 .- 1699-5198. ; 34:3, s. 702-709
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Tidskriftsartikel (refereegranskat)abstract
- Background: The intestinal dysbiosis is common in chronic liver disease and can induce to inflammatory responses and mediate the collagen deposition in the liver. Aim: To evaluate the probiotic Lactobacillus rhamnosus GG (LGG) for the treatment of liver fibrosis in a model of chronic cholestatic liver disease in rats. Methods: Male adult Wistar rats (n = 29) were submitted to common bile duct ligation (BDL groups) or manipulation of common bile duct without ligation (Ctrl groups).Two weeks after surgery, each group was randomly divided to receive 1 ml of PBS (Ctrl and BDL) or PBS containing 2.5 x 10(7) CFU of LGG (Ctrl-P and BDL-P) through gavages for 14 days. Euthanasia occurred 33 days after surgery when samples of blood and liver tissue were collected. Results: The hepatic gene expression of Tlr4, Tnf alpha, IL-6, Tgf beta, and metalloproteinase-2 and -9 were higher in the BDL groups in comparison to Ctrl. The ductular reaction evaluated by immunocontent of cytokeratin-7 (CK7) and the content of collagen were increased in BDL groups. Also, there was an imbalance in the antioxidant defenses (superoxide dismutase and catalase) and an increase in the oxidative stress marker sulfhydryl in BDL groups. The treatment with LGG significantly reduced gene expression of IL-6, collagen deposition, and ductular reaction in hepatic tissue of animals from BDL-P groups. Conclusion: The treatment with the probiotic LGG was able to reduce liver fibrosis, ductular reaction, and hepatic gene expression of IL-6 in a model of cholestatic liver disease in rats.
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| 2. |
- Ljungqvist, Olle, 1954-, et al.
(författare)
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Under nutrition : a major health problem in Europe
- 2009
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Ingår i: Nutrición Hospitalaria. - Madrid, Spanien : Aula Medica Ediciones. - 0212-1611 .- 1699-5198. ; 24:3, s. 369-70
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Tidskriftsartikel (refereegranskat)
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| 3. |
- Mariscal-Arcas, M., et al.
(författare)
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Comparison of methods to evaluate the quality of the Mediterranean diet in a large representative sample of young people in Southern Spain
- 2010
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Ingår i: Nutrición Hospitalaria. - : Aula Médica Ediciones. - 0212-1611 .- 1699-5198. ; 25:6, s. 1006-1013
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Tidskriftsartikel (refereegranskat)abstract
- The objective of this study was to compare the usefulness of two methods to evaluate diet quality in young people in Southern Spain: a new Mediterranean Diet Pattern (MDP) and a modification of the Diet Quality Index-International (DQI-I) for the Mediterranean area. The study population was 3190 schoolchildren aged 8-15 yrs. The questionnaires used were first validated (Bland-Altman plot and Wilcoxon tests) in a randomized sample. The DQI gives a more detailed evaluation of food components, whereas the MDS gives global information on food groups but includes foods characteristically consumed in the Mediterranean region. Highly similar results were obtained using the MDP and the adapted DQI-I, which appear to be equally useful to evaluate diet quality in a Mediterranean population. The fact that we selected the same types of food for both indices may explain the similar overall evaluations. According to these results, both methods appear to be equally appropriate for evaluating diet quality in a Mediterranean population.
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| 4. |
- Mariscal-Arcas, Miguel, et al.
(författare)
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Differences in food intake and nutritional habits between Spanish adolescents who engage in ski activity and those who do not
- 2015
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Ingår i: Nutrición Hospitalaria. - : Aula Medica Ediciones. - 0212-1611 .- 1699-5198. ; 31:2, s. 936-943
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Increasing obesity among adolescents in the industrialized world may result from poor nutritional habits and inadequate exercise.AIM: To determine differences in food intake, nutritional habits, and body mass index between Spanish adolescents who engage in ski activity and those who do not.METHODS: A socio-demographic survey, food frequency questionnaire, 24-hr dietary recall, and physical activity questionnaire were completed by 300 Spanish schoolchildren aged 10 to 18 yrs. RESULTS were compared (Student's t, chi-square and Fisher's exact test) between adolescents engaged (SP) and not engaged (N-SP) in skiing according to their sex.RESULTS: SP adolescents devoted > 4 h/day to physical activity versus < 1 h for N-SP adolescents. No significant differences were found in nutrient intake or nutritional habits between SP and N-SP adolescents. Protein and fat intakes of both groups were above recommended levels. A higher proportion of N-SP than SP males were overweight. Logistic regression analysis showed that the maintenance of a normal weight was favored by the practice of skiing, the consumption of sugar-free drinks, and supplementation with vitamins/mineral salts and was negatively associated with body weight dissatisfaction, intake of nutritional supplements other than vitamins or minerals, and the consumption of snacks.CONCLUSIONS: The diet of this adolescent population was poorly balanced. Engagement in physical activity appears to be a key factor in maintaining a healthy body mass index.
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| 8. |
- Monteagudo, Celia, 1984-, et al.
(författare)
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School dietary habits and incidence of dental caries
- 2015
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Ingår i: Nutrición Hospitalaria. - : Aula Medica Ediciones. - 0212-1611. ; 32:1, s. 383-388
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Tidskriftsartikel (refereegranskat)abstract
- INTRODUCTION: healthy dietary habits are considered to improve oral health and tooth quality. Caries treatment comprises tooth restoration with dental composites and sealants, almost all (> 90%) of which contain bisphenol A (BPA). Study hypotheses were: a) breakfast and oral hygiene habits are important factors in dental caries development; and b) dental caries treatment with epoxy-resins entails a risk of oral exposure to monomers migrating from the polymeric material. We evaluated caries in the teeth of a Spanish school population and determined the percentage treated with dental composites.OBJECTIVE: to relate consumption of breakfast components and oral hygiene habits to dental caries and determine the presence of sealants/composites as potential sources of BPA exposure.METHODS: subjects: 582 schoolchildren from Granada city (Southern Spain) aged 7 yrs; mean (SD) of 7.55 (0.64) yrs.RESULTS: caries was detected in 21.7% of their teeth. Mean breakfast quality index (BQI) score, based on nutritional questionnaires, was 5.18 (1.29). Breakfast with foods rich in simple sugars representing > 5% of total daily energy was consumed by 24% of the population and was significantly associated with caries frequency in binary logistic regression analysis. Biscuit consumption was reported by 35.8% and significantly associated with caries frequency. Breakfast intake of bakery products/ cereals and of dairy products showed a significant inverse association with caries frequency. No significant relationship was observed between caries and BQI score or oral hygiene factors.CONCLUSION: further research is required to elucidate the role of diet in caries and the associated risk of exposure to estrogenic xenobiotics such as BPA.
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| 9. |
- Palacios, Cristina, et al.
(författare)
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Asociaciones entre los niveles de vitamina d y los marcadores de glucosa en mujeres embarazadas y sus bebés en puerto rico
- 2021
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Ingår i: Nutrición Hospitalaria. - : ARAN Ediciones. - 0212-1611 .- 1699-5198. ; 38:6, s. 1224-1231
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Tidskriftsartikel (refereegranskat)abstract
- Objectives: low vitamin D during pregnancy is common and could adversely affect health outcomes. This study evaluated vitamin D status during pregnancy and early in life, and its association with glucose metabolism. Methods: maternal serum 25(OH)D, glucose, and insulin levels were measured longitudinally during pregnancy in Hispanic women with overweight/ obesity (n = 31) and their infants at birth and 4 months. Results: insulin and HOMA-IR levels were higher among women with vitamin D below adequate levels compared to those with adequate levels in pregnancy (p < 0.05). Late in pregnancy, as vitamin D increased by one unit (ng/mL), insulin decreased by 0.44 units and HOMA-IR by 0.09 units. Maternal vitamin D late in pregnancy was correlated with infant vitamin D levels at birth (r = 0.89; p < 0.01) and 4 months (r = 0.9; p = 0.04), and with glucose (r = 0.79; p = 0.03) and insulin (r = 0.83; p = 0.04) at 4 months. Conclusion: maternal vitamin D status was associated with maternal and infant glucose metabolism in this sample.
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