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  • MacLeod, Dominic, et al. (författare)
  • A clinico-pathological study of 79 bronchoscopies in HIV-positive patients
  • 1993
  • Ingår i: Irish Medical Journal. - Dublin. - 0332-3102. ; 86:5, s. 167-169
  • Tidskriftsartikel (refereegranskat)abstract
    • We investigated lung pathology in 61 HIV-positive patients who underwent 79 bronchoscopies. There were 27 cases of pneumo cystis carinii pneumonia (PCP), 22 cases of pyogenic pulmonary infection and six cases of mycobacterial infection. Eleven cases of non-specific interstitial pneumonitis were found and 10 intravenous drug abusers had birefringent pulmonary talc granulomata in biopsy specimens. Women and intravenous drug abusers had higher rates of pyogenic pulmonary infection than men and other risk groups respectively. When compared with a previous survey from the same hospital using the same methodology the present study showed a change in the risk groups with 50 % more intravenous drug abusers, 42% more haemophiliacs and 45% fewer patients with sexually transmitted infection. However, apparent changes in the spectrum of diseases encountered were not significant.
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  • McLoughlin, Paul, et al. (författare)
  • Lung pathology in HIV positive patients
  • 1990
  • Ingår i: Irish Medical Journal. - Dublin : Irish Medical Association. - 0332-3102. ; 83:3, s. 109-111
  • Tidskriftsartikel (refereegranskat)abstract
    • We describe the results of 43 bronchoscopic examinations carried out on 35 patients who were HIV positive.  Of these, 13 were intravenous drug abusers, 13 were homosexual or bisexual, six were haemophiliacs, two were homosexual intravenous drug abusers and one was a heteroexual contact of a drug abuser.  All underwent investigation because of respiratory symptoms.  Aetiological diagnosis could not be made from physical examination, x-ray or routine laboratory tests but, was usually made using bronchoscopy and its associated investigations.  Using these techniques, Pneumocystis carinii pneumonia was the commonest diagnosis (19 cases) followed by bacterial infection.  Mycobacterial infection accounted for two cases and non-specific interstitial pneumonitis accounted for three.  Kaposi's sarcoma was found in one instance and eight investigations were non-diagnostic.
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