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- Valentin, Lil, et al.
(författare)
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Fetal movement in the third trimester of normal pregnancy
- 1986
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Ingår i: Early Human Development. - : Elsevier BV. - 1872-6232 .- 0378-3782. ; 14:3-4, s. 295-306
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Tidskriftsartikel (refereegranskat)abstract
- Changes in fetal motor activity may reflect changes in central nervous function and in the health of the fetus. Recording of fetal movement (FM) has therefore been suggested as a method of assessing fetal well-being. To establish the normal range of FMs in the third trimester of pregnancy, FMs were studied cross-sectionally in 180 and longitudinally in 6 healthy women with normal pregnancies. FMs were recorded simultaneously by the mother and by a FM detector using four piezo-electric crystals attached to the maternal abdomen. The recordings lasted for 45 min (cross-sectional study) or 30 min (longitudinal study). The median numbers of FMs recorded during 45 min by the FM detector and by the mother were 85 (2.5th percentile, 14; 97.5th percentile, 232) and 41 (2.5th percentile, 10; 97.5th percentile, 135), respectively. The median 45-min incidences of FMs recorded by the FM detector and by the mother were 8.1% (2.5th percentile, 1.3; 97.5th percentile, 30.2) and 3.7% (2.5th percentile, 0.9; 97.5th percentile, 15.6), respectively. Neither the number nor the incidence of FMs changed appreciably as gestational age advanced. The interindividual variance in the number and incidence of FMs was two to three times greater than the intra-individual variance (longitudinal study). The large variation in the quantity of FMs recorded during 30 and 45 min limits the value of using quantitative FM recording for antepartum fetal monitoring. Individualized normal limits of the quantity of FMs might be preferable to general limits.
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| 2. |
- Eriksson, Mats, 1959-, et al.
(författare)
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Oral glucose and venepuncture reduce blood sampling pain in newborns
- 1999
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Ingår i: Early Human Development. - 0378-3782 .- 1872-6232. ; 55:3, s. 211-218
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Tidskriftsartikel (refereegranskat)abstract
- The objectives of this study were to measure pain symptoms in healthy fullterm newborns undergoing routine blood sampling with different methods. The 120 study subjects were randomly allocated to one of four groups with 30 babies in each, namely venepuncture or heel stick, with or without oral glucose administration. Pain was assessed from the duration of crying within the first 3 min, the Premature Infant Pain Profile (PIPP) and changes in heart rate. When the babies received 1 ml 30% glucose prior to skin puncture there was no significant difference between the heel stick and venepuncture group either in mean crying time (12.9 and 11.6 s, respectively) or in PIPP score (3.9 and 3.3). When no glucose was given crying time was 57.3 s in the heel stick group and 26.8 s in the venepuncture group (P=0.0041) and the mean PIPP scores were 8.4 and 6.0, respectively (P=0.0458). This study suggests that if oral glucose is given prior to skin puncture the choice of blood sampling method has no impact on the pain symptoms.
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| 4. |
- Hermansson, Liselotte, 1954-, et al.
(författare)
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Upper limb deficiencies in Swedish children : a comparison between a population-based and a clinic-based register
- 2001
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Ingår i: Early Human Development. - 0378-3782 .- 1872-6232. ; 63:2, s. 131-144
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: To validate information in the Swedish Register for Congenital Malformations (SRCM).METHODS: A comparison was made with a clinic-based register kept at the Limb Deficiency and Arm Prosthesis Centre (LDAPC). The report frequency and the quality of the information in SRCM were analysed. Cases were classified according to a detailed, clinically relevant classification, the ISO 8548-1:89 method.OUTCOME MEASURES: The completeness of SRCM was first estimated. The Kappa statistic was then used to assess the agreement between the two registers regarding individual categories and across all categories.RESULTS: For the period 1973-1987, we found 125 cases of upper limb reduction deficiencies (ULRD) in the clinic-based register, of which 117 was found in the national register. The completeness of SRCM was thus estimated to be 94% (95% confidence interval 89-98%). The inter-register agreement varied from almost perfect agreement in laterality of deficiency (Kappa 0.98) to substantial agreement in type and level of deficiency (Kappa 0.72-0.79). For specific levels of transverse deficiency, however, the agreement varied between -0.05 and 0.66.CONCLUSIONS: The results indicate that SRCM, with its calculated underestimation of 6%, can be used for studying the prevalence of ULRD in Sweden. However, as SRCM is a surveillance register, the quality of some information seems to be low, making detailed description of cases difficult. Use of the population register data for clinical purposes could therefore result in lower validity. Additional information and follow-up of specific cases are therefore recommended.
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