| 1. |
- Alfredsson, Joakim, et al.
(författare)
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Multiple Chronic Conditions in Older Adults with Acute Coronary Syndromes
- 2016
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Ingår i: Clinics in Geriatric Medicine. - : W B SAUNDERS CO-ELSEVIER INC. - 0749-0690 .- 1879-8853. ; 32:2, s. 291-
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Tidskriftsartikel (refereegranskat)abstract
- Older adults presenting with acute coronary syndromes (ACSs) often have multiple chronic conditions (MCCs). In addition to traditional cardiovascular (CV) risk factors (ie, hypertension, hyperlipidemia, and diabetes), common CV comorbidities include heart failure, stroke, and atrial fibrillation, whereas prevalent non-CV comorbidities include chronic kidney disease, anemia, depression, and chronic obstructive pulmonary disease. The presence of MCCs affects the presentation (eg, increased frequency of type 2 myocardial infarctions [MIs]), clinical course, and prognosis of ACS in older adults. In general, higher comorbidity burden increases mortality following MI, reduces utilization of ACS treatments, and increases the importance of developing individualized treatment plans.
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| 2. |
- Cederholm, Tommy E., et al.
(författare)
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Toward a Definition of Sarcopenia
- 2011
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Ingår i: Clinics in Geriatric Medicine. - : Elsevier BV. - 0749-0690 .- 1879-8853. ; 27:3, s. 341-353
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Tidskriftsartikel (refereegranskat)abstract
- The definition of sarcopenia has been thoroughly discussed by scientific stakeholders and industry representatives to increase the clinical applicability of the concept. The pooled consensus from 3 of 5 recent and parallel processes, of which 2 are pending, is that sarcopenia is mainly, but not only, an age-related condition defined by the combined presence of reduced muscle mass and muscle function. Contributing factors to sarcopenia are senescence, chronic disease, physical inactivity, and poor food intake. Cachexia may be considered as one etiologic pathway of an accelerated sarcopenia. The adjusted and extended definitions of sarcopenia promote the clinical use of the concept.
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| 3. |
- Hovstadius, Bo, 1955-, et al.
(författare)
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Factors leading to excessive polypharmacy.
- 2012
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Ingår i: Clinics in Geriatric Medicine. - : Elsevier. - 0749-0690 .- 1879-8853. ; 28:2, s. 159-172
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Tidskriftsartikel (refereegranskat)abstract
- There are numerous risk factors for patients to develop excessive polypharmacy. The most prominent risk factors are associated with sociodemographics and the patients’ conditions. Risk factors associated with patient behavior, such as patient’s self medication with all types of medications, have not been observed to the same extent but might be at the same level of importance for patients developing excessive polypharmacy. Risk factors related to physicians, and the interaction between patient and physician, are studied to a much lesser extent. The few studies conducted regarding the large variation in physicians’ individual prescribing practices, in terms of polypharmacy, add another perspective to the complexity of the area. Interventions aiming to improve communication between GP and hospital specialist, to create support systems for medical reviews that include all patients’ medications, and to improve the knowledge of multiple prescribing might have the largest potential to better manage excessive polypharmacy.
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| 4. |
- Michel, Jean-Pierre, et al.
(författare)
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Frailty, Exercise and Nutrition
- 2015
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Ingår i: Clinics in Geriatric Medicine. - : Elsevier BV. - 0749-0690 .- 1879-8853. ; 19:3, s. 375-387
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Tidskriftsartikel (refereegranskat)abstract
- This article first reports the spontaneous course of frailty conditions, and then focuses on randomized, controlled frailty interventions (such as physical exercise, nutrition, combined exercise plus nutrition, and multifactorial interventions) or metaanalysis in community-dwelling older adults or volunteers published in 2012, 2013, and 2014. The main take-home messages that emerge from recent literature are summarized.
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