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- Henriksson, Karl-Gösta, 1928-, et al.
(författare)
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The promise of N-methyl-D-aspartate receptor antagonists in fibromyalgia
- 2002
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Ingår i: Rheumatic Disease Clinics of North America. - 0889-857X .- 1558-3163. ; 28:2, s. 343-351
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Tidskriftsartikel (refereegranskat)abstract
- There is strong evidence that intravenous administration of ketamine following a standardized protocol could be used as a diagnostic test for a central sensitization in the central nervous system in patients with FM. The combination of a weak opioid and an NMDA-receptor antagonist with few side effects is presently a promise for treatment of pain in a subgroup of patients with FM. The response to intravenously administered ketamine may help select patients for this treatment modality.
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| 6. |
- Englund, Martin, et al.
(författare)
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The meniscus in knee osteoarthritis.
- 2009
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Ingår i: Rheumatic Disease Clinics of North America. - : Elsevier BV. - 0889-857X. ; 35:3, s. 579-579
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Tidskriftsartikel (refereegranskat)abstract
- The meniscus is a critical tissue in the healthy knee joint because of its shock absorption and load distribution properties. Meniscal damage is a frequent finding on MRI of the osteoarthritis (OA) knee. The damage appears as horizontal, flap, or complex tears; meniscal maceration; or destruction. Asymptomatic meniscal lesions are common incidental findings on knee MRI of the middle-aged or older person. This challenges the health professional in choosing the best treatment. A meniscal tear can lead to knee OA, but knee OA can also lead to a spontaneous meniscal tear. A degenerative meniscal lesion often suggests early-stage knee OA. Surgical resection of nonobstructive degenerate lesions may merely remove evidence of the disorder while the OA and associated symptoms proceed.
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| 7. |
- Englund, Martin
(författare)
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The role of the meniscus in osteoarthritis genesis.
- 2008
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Ingår i: Rheumatic Disease Clinics of North America. - : Elsevier BV. - 0889-857X. ; 34:3, s. 573-573
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Tidskriftsartikel (refereegranskat)abstract
- The menisci play a critical protective role for the knee joint through shock absorption and load distribution. Currently, the consensus in surgical treatment of meniscal tears is to preserve as much functional meniscal tissue as possible. The health professional is challenged to choose the best treatment, both in the short- and in the long-term. A degenerative lesion in the middle-aged or older patient could suggest early-stage knee osteoarthritis and should be treated accordingly. Surgical resection of nonobstructive degenerate lesions may remove only the evidence of the disorder while the osteoarthritis degradation proceeds. Well-designed randomized, controlled clinical trials are needed.
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| 10. |
- Riordan, Edward A., et al.
(författare)
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The Health and Structural Consequences of Acute Knee Injuries Involving Rupture of the Anterior Cruciate Ligament
- 2013
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Ingår i: Rheumatic Disease Clinics of North America. - : Elsevier BV. - 0889-857X. ; 39:1, s. 107-122
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Tidskriftsartikel (refereegranskat)abstract
- Although there is an abundance of literature regarding the development of knee osteoarthritis after rupture of the anterior cruciate ligament (ACL), the mechanism underlying this link is not clear. Recent studies have reported that several factors may be predictive of the development of osteoarthritis, including damage to the menisci and articular cartilage during the initial trauma, altered knee biomechanics after injury, and episodic instability. This article summarizes recent developments in the understanding of the joint damage resulting from an ACL tear, and the influence that current and future treatment methods may have on the long-term progression to osteoarthritis.
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