| 1. |
- Ekberg, Olle, et al.
(författare)
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Radiologic evaluation of dysphagia
- 1999
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Ingår i: Abdominal Imaging. - : Springer Science and Business Media LLC. - 0942-8925 .- 1432-0509. ; 24:5, s. 444-444
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Tidskriftsartikel (refereegranskat)
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| 2. |
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| 3. |
- Olsson, Rolf, et al.
(författare)
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Solid-state computerized manometry improves diagnostic yield in pharyngeal dysphagia: simultaneous videoradiography and manometry in dysphagia patients with normal barium swallows
- 1995
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Ingår i: Abdominal Imaging. - 0942-8925. ; 20:3, s. 230-235
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE: Dynamic barium radiology with cine- or video recording has been the most frequently used technique for assessing patients with pharyngeal dysphagia. Although the diagnostic yield of the barium swallow has been high, many patients with pharyngeal dysphagia have normal dynamic barium radiology and remain a diagnostic dilemma. Could manometry add important diagnostic information in these patients? MATERIAL AND METHODS: We examined 19 patients (12 men and 7 women, mean age 47 years, range 19-69 years) with pharyngeal dysphagia but a normal barium swallow with simultaneous videoradiography and pharyngeal manometry and compared their manometry to that found in 24 normal volunteers (11 men and 13 women, mean age 37 years, range 23-59 years). RESULTS: Comparing mean values, the patient group showed statistically significant differences from the control group for eight of 10 manometric parameters. Fourteen of 19 patients showed at least one (five patients) and in most cases multiple (nine patients) manometric abnormalities (values exceeding normal mean by +/- 2SD) which might have contributed to their dysphagia: five patients with high upper esophageal sphincter (UES) resting pressures, five with high UES residual pressures, three with weak pharyngeal contractions, three with pharyngeal "spasms," seven with prolonged contraction/relaxation times, five with reduced compliance, and seven with UES/P incoordination. CONCLUSIONS: Solid-state computerized manometry is a useful adjunct to videoradiography and can provide potentially important additional information in the diagnosis of dysphagia patients.
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| 4. |
- Solvig, J, et al.
(författare)
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Ultrasound examination of the small bowel: comparison with enteroclysis in patients with Crohn disease
- 1995
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Ingår i: Abdominal Imaging. - 0942-8925. ; 20:4, s. 323-326
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND: Screening for inflammatory small bowel disease has hereto relied on barium examination, usually performed after duodenal intubation. A noninvasive technique for imaging of the small bowel in such patients would be preferable. METHODS: A total of 59 patients were included in the study. A small bowel barium examination (SBE) was performed after duodenal intubation using a barium and air double-contrast technique. Ultrasound (US) of the right lower quadrant was performed with a 3.5- or 5-MHz transducer. The patients fasted overnight. RESULTS: In 37 of 39 patients with a normal SBE, US was also normal. In 20 patients, SBE showed lesions compatible with Crohn disease and in 18 of these the US study showed thickening of the bowel wall. One of these patients later tested positive for Yersinia enterocolitica. There were two false-positive and two false-negative US examinations. For detection of inflammatory disease of the small bowel, US was calculated to have a sensitivity of 0.95, specificity of 0.93, accuracy of 0.93, predictive value of a positive test was 0.90, and a predictive value of a negative test was 0.95. CONCLUSIONS: US, therefore, seems to be a reliable method in the workup of patients suspected of having inflammatory small bowel disease. Thereby, US probably can select patients for SBF.
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| 5. |
- Uher, Petr, et al.
(författare)
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Aneurysms of the pancreaticoduodenal artery associated with occlusion of the celiac artery
- 1995
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Ingår i: Abdominal Imaging. - 0942-8925. ; 20:5, s. 470-473
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Tidskriftsartikel (refereegranskat)abstract
- Aneurysms of the pancreaticoduodenal artery are rare and may be associated with celiac artery stenosis or occlusion. Twenty-eight patients are reported in the literature. The diagnostic findings and therapeutic alternatives of four additional patients form the basis of this report. One patient with ruptured pancreaticoduodenal aneurysm was successfully treated by transcatheter embolization, and one patient was treated surgically; both patients had an uneventful recovery. In the remaining two patients, the aneurysms were left untreated. One patient died 1 year later of an unrelated cause, and the other patient is symptom-free after 2 years.
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| 6. |
- Coquand, Thierry, 1961, et al.
(författare)
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Generating non noetherian modules constructively
- 2004
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Ingår i: Manuscripta mathematica. - : Springer Science and Business Media LLC. - 0025-2611 .- 1432-1785. ; 115:4, s. 513-520
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Tidskriftsartikel (refereegranskat)abstract
- In [6], Heitmann gives a proof of a Basic Element Theorem, which has as corollaries some versions of the "Splitting-off" theorem of Serre and the Forster-Swan theorem in a non Noetherian setting. We give elementary and constructive proofs of such results. We introduce also a new notion of dimension for rings, which is only implicit in [6] and we present a generalisation of the Forster-Swan theorem, answering a question left open in [6].
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| 7. |
- Lindehell, Henrik, 1984-, et al.
(författare)
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Proximity ligation assays of protein and RNA interactions in the male-specific lethal complex on Drosophila melanogaster polytene chromosomes
- 2015
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Ingår i: Chromosoma. - : Springer Science and Business Media LLC. - 0009-5915 .- 1432-0886. ; 124:3, s. 385-395
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Tidskriftsartikel (refereegranskat)abstract
- In Drosophila, the male-specific lethal (MSL) complex specifically targets the male X chromosome and participates in a twofold increase in expression output leading to functional dosage compensation. The complex includes five proteins and two non-coding RNAs (ncRNAs). A number of additional associated factors have also been identified. However, the components' roles and interactions have not been fully elucidated. The in situ proximity ligation assay (PLA) provides a sensitive means to determine whether proteins and other factors have bound to chromosomes in close proximity to each other, and thus may interact. Thus, we modified, tested, and applied the assay to probe interactions of MSL complex components on polytene chromosomes. We show that in situ PLA can detect and map both protein-protein and protein-ncRNA interactions on polytene chromosomes at high resolution. We further show that all five protein components of the MSL complex are in close proximity to each other, and the ncRNAs roX1 and roX2 bind the complex in close proximity to MLE. Our results also indicate that JIL1, a histone H3 Ser10 kinase enriched on the male X chromosome, interacts with MSL1 and MSL2, but not MSL3 of the MSL complex. In addition, we corroborate proposed interactions of the MSL complex with both CLAMP and TopoII.
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| 8. |
- Ahmed, Sheikh Ali, et al.
(författare)
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Distribution of preservatives in thermally modified Scots pine and Norway spruce sapwood
- 2013
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Ingår i: Wood Science and Technology. - : Springer Science and Business Media LLC. - 0043-7719 .- 1432-5225. ; 47:3, s. 499-513
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Tidskriftsartikel (refereegranskat)abstract
- Studying the impregnation and distribution of oil-based preservative in dried wood is complicated as wood is a nonhomogeneous, hygroscopic and porous material, and especially of anisotropic nature. However, this study is important since it has influence on the durability of wood. To enhance the durability of thermally modified wood, a new method for preservative impregnation is introduced, avoiding the need for external pressure or vacuum. This article presents a study on preservative distribution in thermally treated Scots pine (Pinus sylvestris L.) and Norway spruce (Picea abies (L.) Karst.) sapwood using computed tomography scanning, light microscopy, and scanning electron microscopy. Secondary treatment of thermally modified wood was performed on a laboratory scale by impregnation with two types of preservatives, viz. Elit Träskydd (Beckers) and pine tar (tar), to evaluate their distribution in the wood cells. Preservative solutions were impregnated in the wood using a simple and effective method. Samples were preheated to 170°C in a drying oven and immediately submerged in preservative solutions for simultaneous impregnation and cooling. Tar penetration was found higher than Beckers, and their distribution decreased with increasing sample length. Owing to some anatomical properties, uptake of preservatives was low in spruce. Besides, dry-induced interstitial spaces, which are proven important flow paths for seasoned wood, were not observed in this species.
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| 9. |
- Lampinen, Maria, 1965-, et al.
(författare)
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Accumulation, activation and survival of neutrophils in ulcerative colitis : regulation by locally produced factors in the colon and impact of steroid treatment
- 2008
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Ingår i: International Journal of Colorectal Disease. - : Springer Science and Business Media LLC. - 0179-1958 .- 1432-1262. ; 23:10, s. 939-946
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Tidskriftsartikel (refereegranskat)abstract
- BACKGROUND AND AIMS: Neutrophil granulocytes infiltrate the intestinal mucosa in active ulcerative colitis (UC), and may contribute to tissue damage and inflammation. The aim of this investigation was to study the importance of locally produced factors and the impact of steroid treatment on neutrophil functions in UC. PATIENTS AND METHODS: Intestinal perfusion fluids from 11 patients with active distal UC before and after seven and 28 days of treatment with prednisolone and from seven control patients were used in the study. Neutrophil migration towards perfusion fluid was measured in a microchemotaxis chamber. The effect of perfusion fluids on neutrophil activation was assessed as the surface expression of CD66b by flow cytometry. Neutrophil survival was evaluated by staining with propidium iodide, annexin V, and fluorescein di-acetate. We also assessed the viability of freshly isolated tissue neutrophils from rectal biopsy samples. RESULTS: Perfusion fluids from untreated patients caused increased migration, activation, and survival of neutrophils. Perfusion fluids collected after treatment had no effect on neutrophil migration, but some of the activation and anti-apoptotic effects remained after 7 days. Anti-granulocyte-macrophage colony-stimulating factor (GM-CSF) inhibited the anti-apoptotic effect of perfusion fluids. Rectal tissue neutrophils from patients with active proctitis had increased viability compared to patients with inactive proctitis and control subjects. CONCLUSIONS: These data show that mediators in the colon of patients with active UC stimulate the migration, activation, and survival of neutrophils. The activities were partly neutralized by topical steroid treatment. We also identified GM-CSF as an anti-apoptotic factor for neutrophils in inflamed colon.
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| 10. |
- Ågren, Jon, et al.
(författare)
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Selection on floral display in insect-pollinated Primula farinosa : Effects of vegetation height and litter accumulation
- 2006
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Ingår i: Oecologia. - : Springer Science and Business Media LLC. - 0029-8549 .- 1432-1939. ; 150:2, s. 225-232
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Tidskriftsartikel (refereegranskat)abstract
- Grazing reduces litter thickness and vegetation height and may thereby indirectly affect reproductive success and selection on floral characters in plants with prostrate growth. Reductions in litter thickness and vegetation height should influence both the resource status of plants with leaves positioned close to the ground and the significance of inflorescence height for interactions with pollinators and seed predators. We experimentally examined how simulated grazing of surrounding vegetation affected pollen limitation, fruit predation and fecundity of short-scaped and long-scaped Primula farinosa, which differ markedly in floral display and therefore in expected attractiveness to pollinators. Litter removal and pruning of surrounding vegetation increased fruit and seed production per plant in the year of the treatment and the probability of flowering in the following year. Pollen limitation of fruit and seed production was stronger in the short-scaped morph than in the long-scaped morph, but was not significantly affected by litter removal and simulated grazing of surrounding vegetation. Supplemental hand-pollination reduced seed size in the year of the treatment and flowering probability in the second year, and these effects did not differ among scape morphs or grazing treatments. The results suggest that grazing indirectly favours seed production in P. farinosa, mainly because it increases the resource status of plants that escape damage. Contrary to expectation, there was no strong evidence that litter accumulation and tall vegetation increase the severity of pollen limitation or reduce the relative performance of the short-scaped morph.
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