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| 2. |
- Abd El-Wahed, Aida A., et al.
(författare)
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Unravelling the beehive air volatiles profile as analysed via solid-phase microextraction (SPME) and chemometrics
- 2021
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Ingår i: Journal of King Saud University – Science. - : Elsevier BV. - 1018-3647 .- 2213-686X. ; 33:5
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Tidskriftsartikel (refereegranskat)abstract
- Objective: Beehive air therapy is recognized as a potential remedy for treating asthma, bronchitis, lung fibrosis, and respiratory tract infections. Developed countries in which beehive air therapy is currently authorized include Germany, Hungary, Slovenia, and Austria. However, scientific proof of its efficacy is lacking which warrants further chemical and biological analyses as a proof of concept. In this study, beehive air volatile profile was determined for the first time along with its individual components (bees, venom, honey, and beeswax).Methods: Volatile compounds were collected from beehive air using solid phase micro-extraction (SPME) coupled to gas chromatography-mass spectrometry (GC–MS). Antimicrobial assay of the air released from 4 beehive products was further performed against Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, and multi drug-resistant Staphylococcus aureus (MRSA) using the in vitro agar-well diffusion and microtiter plate assays.Results and conclusions: A total of 56 volatile compounds were identified from beehive air, venom, bee insect and wax air including 6 fatty acids, 6 alcohols, 10 aldehydes, 5 esters, 1 ether, 9 hydrocarbons, 1 phenol, 7 ketones, 1 nitrogenous compound and 10 terpenes. The most abundant constituents were short-chain fatty acids (26.32%) while the lowest were the nitrogenous compounds (0.82%). The principal component analysis (PCA) scores plot of the UPLC/MS dataset showed the similarity of the beehive air to the insect bee's aroma profile. With regards to antimicrobial assay, beehive air and venom exerted the strongest antimicrobial activity among the examined bee products against S. aureus, K. pneumoniae, A. baumannii, and MRSA in agar-well diffusion assay but failing to exert an effect using microtiter plate assay as in case of bee venom against the aforementioned bacteria.
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| 4. |
- Asmoay, Ahmed, et al.
(författare)
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Water quality assessment in dry regions using statistical methods
- 2023
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Ingår i: Journal of King Saud University - Science. - : Elsevier. - 1018-3647. ; 35:5
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Tidskriftsartikel (refereegranskat)abstract
- Water demands have increased even more in recent decades because of the high population density. Surface and groundwater resources are insufficient to meet these demands. As a result, governments have turned to the treatment of sewage water. Sewage water contains multiple types of contamination, creating a major health risk. In the research region, 48 water samples were obtained, including 18 samples of surface water and 30 samples of groundwater. The Canadian Council Water Quality Index (CCWQI) program calculates the water quality index to evaluate the water quality for drinking and human use. The World Health Organization (WHO) and the Egyptian Ministry of Health (EMH) determined regulatory limits for drinking water and each value of the investigated parameter connected with them. According to the findings, 79% of the tested water samples are safe to drink and are excellent for human and wildlife use. Due to infiltration or recharging of groundwater with drainage water, as well as the involvement of dissolution, leaching processes, and anthropogenic activities that damage human health, animals, and some plants, these samples are unfit for drinking and domestic consumption. The heavy metal level of Cd and Pb in the examined water samples was found to be above WHO and EMH acceptable limits. Furthermore, due to oral exposures, the examined water samples may cause complex health concerns such as non-carcinogenic and carcinogenic influences for children over adults due to a reduction in children's immunity. As a result, water treatment should be carried out in the examined region to protect the health of the residents.
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| 5. |
- Aziz, Nudrat, et al.
(författare)
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Erythroid induction activity of Aquilegia fragrans and Aquilegia pubiflora and identification of compounds using liquid chromatography-tandem mass spectrometry
- 2021
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Ingår i: JOURNAL OF KING SAUD UNIVERSITY SCIENCE. - : Elsevier. - 1018-3647 .- 2213-686X. ; 33:1
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Tidskriftsartikel (refereegranskat)abstract
- Aquilegia fragrans (AF) and Aquilegia pubiflora (AP) are the two medicinally important species of genus Aquilegia used for the treatment of various diseases and infections. This paper describes the potential of fetal hemoglobin induction activity of the methanolic extracts of AF and AP in K562 cell line. AF and AP have shown 27.147 +/- 1.376 and 32.786 +/- 1.048 percent erythroid induction, respectively at 15.625 (mg/mL) concentration which suggested that both plants can be the source of potential fetal hemoglobin inducers and may be used for the treatment of beta-thalassemia. Phytochemical analyses of both species were also evaluated by using high-resolution LC-ESI-QTOF-MS/MS techniques. A Total of thirty compounds were identified using positive and negative ionization modes. The identification was based on the matching of high-resolution masses, isotopic pattern, and MS/MS fragmentation. Several statistical analyses were performed to evaluate the distribution of compounds in both species. Identified compounds belong to various classes including flavonoids, steroids, lignans, terpenoids, benzofuran and coumarins. The established chemical fingerprints will be helpful in standardization and quality control of plant extracts.
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| 6. |
- Faisal, Ayad A.H., et al.
(författare)
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COMSOL multiphysics 3.5a package for simulating the cadmium transport in the sand bed-bentonite low permeable barrier
- 2020
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Ingår i: Journal of King Saud University - Science. - Netherlands : Elsevier. - 1018-3647. ; 32:3, s. 1944-1952
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Tidskriftsartikel (refereegranskat)abstract
- Here, batch study for Iraqi bentonite-cadmium aqueous solution interaction was conducted with condi- tions of contact time ::; 120 min, sorbent dosage from 0.05 to 1 g per 100 mL and shaking speed from 50 to 300 rpm for initial concentration of 50 mg/L with initial pH of 3 to simulate the acetogenic phase in the sanitary landfill. The best conditions were 1 h, 0.7 g/100 mL and 250 rpm, respectively to obtain the high- est removal (90%). The sorption data were well formulated by Freundlich and Langmuir models with determination coefficient (R2) 2: 0.98 and sorption capacity of 145.3 mg/g; so, the removal process gov- erned by the physico-chemical forces. The average coefficient of the hydraulic conductivity was found equal to 1.98 x 10-10 m/s and this is suitable for low permeable barrier (LPB). Finally, the predictions of COMSOL package were presented satisfactory simulation for the cadmium concentrations within two-dimensional physical model packed with sand aquifer and Iraqi bentonite. Two configurations of LPB were evaluated for restriction of contaminant front migration and the results proved that the sur- rounding of the location required to protect it from three sides against to the flow direction can be more dependable from continuous configuration.
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| 7. |
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| 8. |
- Mohamed, Rania Ali El Hadi, et al.
(författare)
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Detection of some haemorrhagic fever viruses in wild shrews collected from different habitats in Saudi Arabia : first record in the Middle East
- 2021
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Ingår i: Journal of King Saud University Science. - : Elsevier. - 1018-3647 .- 2213-686X. ; 33:8
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Tidskriftsartikel (refereegranskat)abstract
- Shrews (family Soricidae) are tiny mole-shaped mammals belong to the order Eulipotyphla. The main objective of this study is to screen wild specimens of shrews for specific RNA viruses cause hemorrhagic fevers. Wild specimens of shrews were collected from rural areas in Kingdom of Saudi Arabia. Collection of shrews were carried out from the traps then identified using the classical morphological keys. Specimens were dissected then extraction of single stranded RNA of shrews was performed from internal organs including lungs, livers, kidneys, and stomach using QiagenRNeasy Mini Kit. RT-PCR was utilized for screening of Crimean- Congo hemorrhagic fever virus (CCHFV), Rift Valley Fever Virus (RVFV), and Chikengunya virus (CHIKV), and Sindbis virus (SINV). The results revealed SINV, CHIKV, and CCHFV were all found in the internal viscera of shrews in four different groups. This demonstrated that the viruses were propagating and spreading throughout the tissues of the shrews.Conclusions: Depending to our knowledge results of this study constitute first record in Kingdom Saudi Arabia and significantly highlight some of the neglected wild reservoirs of arboviruses; therefore future studies should focus on evaluating other hosts, including bats.
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| 9. |
- Noreen, K., et al.
(författare)
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Some new constructions of minimal efficient circular nearly strongly balanced neighbor designs
- 2023
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Ingår i: Journal of King Saud University - Science. - : Elsevier. - 1018-3647. ; 35:6
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Tidskriftsartikel (refereegranskat)abstract
- Neighbor designs are popular to control neighbor effects. Among neighbor designs, strongly balanced neighbor designs are important to estimate treatment effects and neighbor effects independently. Minimal circular strongly balanced neighbor designs (MCSBNDs) can be obtained only for odd v (number of treatments). For v even, minimal circular nearly strongly balanced neighbor designs are used which satisfied all conditions of MCSBNDs except that the treatment labeled as (v − 1) does not appear as its own neighbor. These designs can be converted directly in some other useful classes of neighbor designs. These designs are efficient to minimize the bias due to the neighbor effects.
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| 10. |
- Rashid, Hayder M., et al.
(författare)
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Novel material from immobilization of magnesium oxide and cetyl trimethyl ammonium bromide nanoparticles onto waterworks sludge for removing methylene blue from aqueous solution
- 2023
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Ingår i: Journal of King Saud University - Science. - : Elsevier. - 1018-3647. ; 35:6
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Tidskriftsartikel (refereegranskat)abstract
- Utilizing the waterworks sludge byproduct in the treatment of wastewater contained methylene blue dye is one approach that has been taken in an effort to lessen the difficulties that are associated with managing such byproduct. The prime aim of this work is manufacturing of novel sorbent from co-precipitation of magnesium oxide nanoparticles on the surfaces of waterworks sludge in the existence of cetyl trimethyl ammonium bromide surfactant. Surfactant 0.04 g/50 mL, dose of sludge 2 g/50 mL, and pH 12 were the most efficient preparation parameters to remove 75.31% of adopted dye. The adsorption studies were conducted under various conditions of contact time (0–240 min), concentration of dye (10–300 mg/L), sorbent mass (0.05–1.5 g), and solution pH (3–12). The best values of batch parameters were identical to the highest percentages of contaminant removal. Results proved that the magnesium oxide nanoparticles are attached to the sludge surfaces. Freundlich and pseudo-second-order models have perfectly described sorption results with 59.92 mg/g maximum sorption capacity. The breakthrough curves can be accurately described by the Bohart-Adams model. The outputs of continuous tests have been paved the way for future usage of the prepared sorbent in the field permeable reactive barrier technology.
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