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- Burgu, Berk, et al.
(författare)
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Both dorsal and ventral flaps can be used in previously circumcised hypospadic adults with comparable success rates.
- 2010
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Ingår i: International urology and nephrology. - : Springer Science and Business Media LLC. - 1573-2584 .- 0301-1623. ; 42:3, s. 689-95
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Tidskriftsartikel (refereegranskat)abstract
- To compare dorsal and ventral dartos flap outcomes for tubularized incised-plate urethroplasty (TIPU) in terms of success, complication rates and cosmetic appearance in adult circumcised hypospadic men.Forty-two circumcised adult men underwent primary distal or midpenile hypospadias repair for cosmetic reasons by a single surgeon in a prospective randomized trial. Twenty-two patients were randomly selected for TIPU repair with dorsal (Group1, mean age 22.3 years) dartos flap as second layer. Twenty patients were randomly selected for TIPU repair with ventral dartos flap (Group2, mean age 21.1 years). Satisfaction questionnaires were answered by patients before surgery and at postoperative 6 weeks. The operating surgeon also filled in the form blindly at the same postoperative period. The differences between pre and postoperative satisfaction scores for each group were also evaluated. Preoperatively, all cases were evaluated with uroflowmetry and compared with postoperative results measured at 6th week of surgery. P < 0.05 was considered as significant.Mean follow-up was 24 months (4-28). Complications were encountered in 18 and 20% of the patients in groups 1 and 2, respectively. Complications were urethrocutaneous fistula, meatal stenosis, retrusive/proximal meatus and residual curvature. Success rates were 82 and 80%, respectively. No differences were seen in overall satisfaction between the two groups (P = 0.07).Outcome of hypospadias repair in circumcised adults for cosmetic reasons is similar to uncircumcised hypospadics previously mentioned in the literature. Both dorsal and ventral flaps can be used in previously circumcised hypospadic adults with comparable satisfaction and complication rates and uroflow findings.
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- Dousdampanis, Periklis, et al.
(författare)
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Two icodextrin exchanges per day in peritoneal dialysis patients with ultrafiltration failure: one center's experience and review of the literature
- 2011
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Ingår i: International Urology and Nephrology. - : Springer Science and Business Media LLC. - 1573-2584 .- 0301-1623. ; 43:1, s. 203-209
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Tidskriftsartikel (refereegranskat)abstract
- At present, only one exchange of an icodextrin-based solution is recommended to increase peritoneal ultrafiltration (UF) during long-dwell exchanges in peritoneal dialysis (PD) patients with impaired UF. To review our experience with two icodextrin exchanges per day on net UF and body weight in PD patients with poor UF. Data were analyzed on nine patients with poor UF on chronic PD who were given two icodextrin exchanges per day for 6 months and had various clinical and biochemical parameters assessed monthly. Administration of icodextrin twice daily reduced the body weight in six of nine patients by an average of 2.9 +/- A 1.2 kg, a reduction that was maintained throughout the study; two patients gained 0.5 kg; and, in one patient, the measurements were inadequate. Mean blood pressure was reduced. Mean serum creatinine increased slightly. Serum sodium levels decreased from a mean baseline level of 134 +/- A 3 to 132 +/- A 4 mmol/L at three and six months. Among the diabetics in this group, average daily insulin requirements were 44 +/- A 35 units/day at baseline and 40 +/- A 23 units/day after 6 months. Hb1Ac levels remained stable throughout the study period. The use of two icodextrin exchanges per day reduced body weight in six of the nine patients and appeared to be safe. Long-term prospective studies are needed to assess the contribution of twice-daily icodextrin to the management of peritoneal dialysis patients with ultrafiltration failure and its long-term safety.
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- Elzanaty, Saad
(författare)
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Non-obstructive azoospermia and clinical varicocele: therapeutic options.
- 2013
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Ingår i: International Urology and Nephrology. - : Springer Science and Business Media LLC. - 1573-2584 .- 0301-1623. ; 45:3, s. 669-674
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Forskningsöversikt (refereegranskat)abstract
- Ten to fifteen percent of infertile men are azoospermic, and sixty percent of these men have been classified as having non-obstructive azoospermia (NOA). NOA results from testicular failure, and one of the causes of this is the presence of varicocele. Varicocele is observed in 5-10 % of men with NOA. This review discusses the impact of varicocele repair on semen quality and pregnancy rate among men with NOA. Based on the best available evidence, varicocele repair of men with NOA is associated with an improvement in semen quality and pregnancy rate. Thus, it appears to be an effective therapeutic option for this group of men, particularly for those with a female partner who is younger than 35 years of age, before an assisted reproductive technique (ART) is initiated. Semen cryopreservation is recommended once the patient has spermatozoa in the ejaculate. In addition, varicocele repair seems to improve the rate of spermatozoa recovery in testicular sperm extraction for those who requested ART.
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