| 1. |
- Elzanaty, Saad, et al.
(författare)
-
Advances in male reproductive surgery : robotic-assisted vasovasostomy
- 2013
-
Ingår i: Current Urology. - : Ovid Technologies (Wolters Kluwer Health). - 1661-7649. ; 6:3, s. 7-113
-
Forskningsöversikt (refereegranskat)abstract
- It is estimated that 3-6% of all vasectomised men request vasectomy reversal for different reasons. Microsurgical vasovasostomy is the gold standard technique of vasectomy reversal. However, the microsurgical technique is time-consuming and challenging to most urological surgeons. Therefore, alternative methods of vasal anastomosis have been studied including robotic-assisted vasovasostomy. This review discusses the feasibility and practice of robotic-assisted vasovasostomy. Based on the available studies robotic-assisted vasovasostomy is feasible. The reported rate of vasal patency associated with this new technique is similar to that of microsurgical vasovasostomy. There is no clear difference between the 2 approaches in terms of operating time. Robotic-assisted vasovasostomy does not appear to afford significant advantages in the era of vasectomy reversal.
|
|
| 2. |
- Elzanaty, Saad, et al.
(författare)
-
Association between Erectile Function and Biomarkers of Subclinical Atherosclerosis : A Study Based on Middle-Aged Healthy Men from the General Population
- 2016
-
Ingår i: Current Urology. - : Ovid Technologies (Wolters Kluwer Health). - 1661-7649. ; 9:3, s. 119-123
-
Tidskriftsartikel (refereegranskat)abstract
- Introduction: Epidemiological studies suggest atherosclerosis as a common risk factor between cardiovascular diseases and erectile dysfunction (ED). We aimed to determine the association between erectile function and the biomarkers of subclinical atherosclerosis in 119 middle-aged healthy men from the general population. Methods: Erectile function was assessed using the International Index of Erectile Function-5 (IIEF-5). Serum levels of biomarkers of atherosclerosis: Apolipoprotein A, Apolipoprotein B, fibrinogen, and C-reactive protein (CRP) were measured. In addition, demographic data was collected. Results: The mean (SD) of age was 55 years (± 4.0). The prevalence of ED was 50%. There was a negative significant correlation between IIEF-5 and CRP levels (r = -0.20, p = 0.02), and BMI (r = -0.20, p = 0.03), respectively. No significant correlations between IIEF-5 and serum levels of Apolipoprotein A, Apolipoprotein B, and fibrinogen were found (p > 0.05). A positive significant correlation was found between BMI and fibrinogen (r = 0.20, p = 0.01), CRP (r = 0.30, p = 0.001). In a multivariate logistic regression model with IIEF-5 as the dependent variable, CRP was the only biomarker that predicted ED (odds ratio = 1.350; 95 % CI: 1.044-1.754). Conclusions: These results indicate that CRP is a biomarker of subclinical atherosclerosis associated with ED. This association seems to be linked to greater BMI among such men.
|
|
| 3. |
- Elzanaty, Saad, et al.
(författare)
-
Association between PSA Levels and Biomarkers of Subclinical Systemic Inflammation in Middle-Aged Healthy Men from the General Population
- 2016
-
Ingår i: Current Urology. - : Ovid Technologies (Wolters Kluwer Health). - 1661-7649. ; 9:3, s. 148-152
-
Tidskriftsartikel (refereegranskat)abstract
- Introduction: This study was aimed to determine the association between PSA levels and biomarkers of subclinical systemic inflammation based on data from 119 middle-aged healthy men from the general population. Materials and Methods: Serum levels of PSA and biomarkers of systemic inflammation (CRP and fibrinogen) were measured. Demographic data were also collected. Subjects were divided into two groups according to PSA levels; < 2 ng/ml and ≥ 2 ng/ml. Results: The mean (SD) age of men was 55 ± 4.0 years. We found a positive significant correlation between PSA and fibrinogen levels (r = 0.20, p = 0.04), and between CRP and fibrinogen levels (r = 0.60, p = 0.01). On the other hand, no significant correlation between PSA and CRP levels was found. Men with PSA values ≥ 2 ng/ml had significantly higher levels of fibrinogen as compared to those with PSA < 2 ng/ml (2.9 ng/ml vs. 2.4 ng/ml, p = 0.01). In a multivariate regression analysis model adjusted for the age of subjects, BMI, marital status, smoking, snuff, and alcohol intake with serum levels of PSA as a dependent variable, serum level of fibrinogen predicted higher PSA-values (odds ratio = 3.30, 95% CI = 1.05-10.20, p = 0.042). Conclusions: The present results indicate that serum fibrinogen is a biomarker of subclinical systemic inflammation associated with PSA elevation among middle-aged healthy men from the general population.
|
|
| 4. |
- Elzanaty, Saad, et al.
(författare)
-
Association between Serum Testosterone and PSA Levels in Middle-Aged Healthy Men from the General Population
- 2017
-
Ingår i: Current Urology. - : Ovid Technologies (Wolters Kluwer Health). - 1661-7649. ; 10:1, s. 40-44
-
Tidskriftsartikel (refereegranskat)abstract
- Introduction: The aim of the present study was to evaluate the association between serum testosterone and PSA levels in middle-aged healthy men from the general population. Materials and Methods: Based on 119 healthy men from the general population, total testosterone and PSA levels were measured. Demographic data regarding BMI, waist-to-hip ratio, smoking, and alcohol consumption were also collected. Men were classified into two groups according to testosterone levels; hypogonadal (testosterone ≤ 12 nmol/l), and eugonadal (testosterone > 12 nmol/l). Results: The mean age of the subjects was 55 years (range 46-60 years). No significant correlation between serum testosterone and PSA levels was found (p = 0.60). PSA levels were similar when compared between hypogonadal and eugonadal men (1.4 μg/l vs. 1.4 μg/l, p = 0.90).When using a multivariate analysis model adjusted for the age of the subjects, BMI, waist-to-hip ratio, smoking, and alcohol consumption, a positive significant association between testosterone and PSA levels was found (β = 0.03, 95 % CI = 0.003-0.062, p = 0.03). Conclusion: Only after adjusted multivariate analysis, our results indicated that testosterone was associated with PSA levels in middle-aged healthy men.
|
|
| 5. |
- Elzanaty, Saad, et al.
(författare)
-
Effect of microsurgical subinguinal varicocele repair on chronic dull scrotal pain in men with grade II-III lesions
- 2017
-
Ingår i: Current Urology. - : Ovid Technologies (Wolters Kluwer Health). - 1661-7649. ; 9:4, s. 188-191
-
Tidskriftsartikel (refereegranskat)abstract
- Introduction: We aimed to evaluate the effectiveness of microsurgical subinguinal varicocele repair in patients with grade II-III lesions and chronic dull scrotal pain. Materials and Methods: A total of 29 patients with grade II-III varicocele and chronic dull scrotal pain that had a microsurgical subinguinal varicocele repair were included in the study. They were followed-up for 6-12 months including pain assessment and scrotal examination. Results: Of the 29 patients, 28 (97%) reported complete resolution of pain with no palpable varicocele on scrotal examination. No cases of testicular atrophy or hydrocele formation were reported. Conclusion: These results indicated that microsurgical varicocele repair should be considered in patients with grade II-III lesions and chronic dull scrotal pain.
|
|
| 6. |
- Elzanaty, Saad, et al.
(författare)
-
Microsurgical Subinguinal Varicocele Repair of Grade II-III Lesions Associated with Improvements of Testosterone Levels
- 2017
-
Ingår i: Current Urology. - : Ovid Technologies (Wolters Kluwer Health). - 1661-7649. ; 10:1, s. 45-49
-
Tidskriftsartikel (refereegranskat)abstract
- Introduction: The results of reports on the association between varicocele repair and testosterone levels were conflicting. The aim of the present study is, therefore, to investigate the impact of varicocele repair on testosterone levels. Materials and Methods: The study is based on 20 men who experienced microsurgical subinguinal varicoceles repair because of chronic dull scrotal pain. All hormonal profiles available in the clinical records were reviewed. Follow-up evaluation was done at 1 and 12 months after surgery. Men were classified into groups based on the preoperative testosterone levels: euogonadal (serum levels of testosterone > 12 nmol/l), hypogonadal men (serum levels of testosterone ≤ 12 nmol/l). Results: Microsurgical subinguinal varicocele repair was associated with a significant improvements of testosterone levels at 1 and 12 months after surgery as compared to the preoperative levels (13 nmol/l vs. 18 nmol/l, p = 0.03; 13 nmol/l vs. 15 nmol/l, p = 0.01). The same trend was seen in men who were classified as being hypogonadal (7.0 nmol/l vs. 15 nmol/l, p = 0.01; 7.0 nmol/l vs. 10 nmol/l, p = 0.02). No significant improvements in testosterone levels were observed in euogonadal men (p > 0.05). Conclusion: Microsurgical subinguinal varicocele repair was associated with a significant improvements of testosterone levels in men with grade II-III lesions and low preoperative testosterone values.
|
|
| 7. |
|
|
| 8. |
|
|
| 9. |
- Karaköse, Ayhan, et al.
(författare)
-
The Effect of Bisphosphonates on Bone Mineral Density in Metastatic Prostate Cancer Patients Who Are Treated with Anti-Androgen Drugs and Radiotherapy.
- 2014
-
Ingår i: Current urology. - : Ovid Technologies (Wolters Kluwer Health). - 1661-7649. ; 7:4, s. 181-4
-
Tidskriftsartikel (refereegranskat)abstract
- To evaluate the potential effect of bisphosphonates on bone mineral density (BMD) in patients who are treated with anti-androgen drugs and radiotherapy for metastatic prostate cancer.The data of 31 patients with metastatic prostate cancer who were treated with anti-androgen drugs and radiotherapy during a 1-year period were retrospectively reviewed. Patients were divided in 2 groups, in which 17 patients in group 1 were treated with zoledronic acid (4 mg/month, intravenous) and 14 patients in group 2 who did not receive zoledronic acid. BMD was measured before the treatment and at the end of the 1st year by dual energy X-ray absorptiometry. Statistical analyses were performed with the T test.Mean age of the patients was 71.42 ± 6.7(range 59-85) years. A significant increase was noted for pelvic bone, femoral neck, and lumbar vertebrae t scores when pretreatment and 1st year measurements were compared in group 1 (p < 0.05). In group 2 a significant decrease was noted for pelvic bone and femoral neck t scores at the end of the 1st year (p < 0.05). A significant increase was noted for pelvic bone and femoral neck follow-up in BMD values at the end of the 1st year compared to initial measurements in group 1. A significant decrease was noted for lumbar vertebrae follow-up in BMD values at the end of the 1st year when compared to initial values in group 2.Zoledronic acid significantly increases BMD and delays unfavorable outcomes for bones in men who are treated with anti-androgen drugs and radiotherapy for metastatic prostate cancer.
|
|
| 10. |
- Rezanezhad, Babak, et al.
(författare)
-
The Association between Serum Testosterone and Risk Factors for Atherosclerosis
- 2019
-
Ingår i: Current Urology. - : Ovid Technologies (Wolters Kluwer Health). - 1661-7649. ; 13:2, s. 101-106
-
Tidskriftsartikel (refereegranskat)abstract
- Objective: To study the associations between serum testosterone and risk factors for atherosclerosis in 119 men from general population. Methods: Systolic pressure, body mass index (BMI), testosterone, fasting glucose, glucose tolerance test, apolipoprotein A-1 (ApoA-1), apolipoprotein B (ApoB), and ApoB/ApoA-1 ratio were assessed. Subjects classified into hypogonadal (testosterone ≤ 12 nmol/l), and eugonadal men (testosterone > 12 nmol/l). Results: BMI (28 vs. 26 kg/m2, p = 0.01), systolic pressure (129 vs. 123 mmHg, p = 0.03), fasting glucose (5.9 vs. 5.5 mmol/l, p = 0.03), ApoB (1.1 vs. 1.0 g/l, p = 0.03), and ApoB/ApoA-1 ratio (0.8 vs. 0.7, p = 0.03) were higher in hypogonadal compared to eugonadal men, respectively. In adjusted multivariate regression analysis model, testosterone showed negative associations with BMI (β =-1.832, p = 0.030, 95% CI =-3.485-0.180), fasting glucose (β =-0.394, p = 0.011, 95% CI =-0.696-0.091), glucose tolerance test (β =-0.957, p = 0.045, 95% CI =-1.892-0.022), ApoB (β =-0.157, p = 0.017, 95% CI =-0.286-0.029), and ApoB/ApoA-1 ratio (β =-0.118, p = 0.046, 95% CI =-0.234-0.002). Conclusions: These results suggest an inverse association between testosterone levels and risk factors for atherosclerosis.
|
|
