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| 2. |
- Börjesson, Karl, 1982, et al.
(författare)
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A membrane anchored DNA-based energy/electron transfer assembly
- 2008
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Ingår i: Nucleic acids symposium series (2004). - 1746-8272. ; :52, s. 691-691
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Tidskriftsartikel (refereegranskat)abstract
- In this work the trapping and conversion of visible light energy into chemical energy is examined using a supramolecular assembly. This consists of a light absorbing antenna and a porphyrin redox centre both covalently attached to a DNA strand, which in turn is bound to a lipid membrane. The excitation energy is finally trapped as a benzoquinone radical anion that could potentially be used in subsequent chemical reactions.
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| 3. |
- Börjesson, Karl, 1982, et al.
(författare)
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Characterization and use of tricyclic fluorescent nucleic acid base analogues
- 2008
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Ingår i: Nucleic acids symposium series (2004). - 1746-8272. ; :52, s. 3-4
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Tidskriftsartikel (refereegranskat)abstract
- The two recently developed nucleic acid probe molecules tC and tC(O) both have unique properties compared to other molecules in the family of fluorescent base analogues.(1-5) These tricyclic base analogues both form very stable base pairs with guanine and give minimal perturbations to the native structure of DNA.(2) We have found that tC(O) is the brightest fluorescent base analogue reported(4) and that tC also is very bright and has a fluorescence quantum yield that is virtually insensitive to its surrounding microenvironment within the nucleic acid(3). These base analogues have so far been used in FRET-studies of a DNA-polymerase system(6) and in initial anisotropy-studies of DNA-containing systems(4).
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| 4. |
- Clausen, Anders Ranegaard, et al.
(författare)
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A multisubstrate deoxyribonucleoside kinase from plants.
- 2008
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Ingår i: Nucleic acids symposium series. - : Oxford University Press (OUP). - 0261-3166 .- 1746-8272. ; :52, s. 489-490
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Tidskriftsartikel (refereegranskat)abstract
- Deoxyribonucleoside kinases catalyze the rate limiting step during the salvage of deoxyribonucleosides and convert them into the corresponding monophosphate compounds. We have identified and characterized a unique multisubstrate deoxyribonucleoside kinase from plants. The phylogenetic relationship and biochemical properties suggest that this deoxyribonucleoside kinase represents a living fossil resembling the progenitor of the modern animal deoxycytidine, deoxyguanosine and thymidine 2 kinases. The broad substrate specificity makes this enzyme an interesting candidate to be evaluated as a suicide gene in anti-cancer therapy.
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| 5. |
- Hannestad, Jonas, 1981, et al.
(författare)
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Self-assembled DNA photonic wire
- 2008
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Ingår i: Nucleic acids symposium series (2004). - 1746-8272. ; :52, s. 685-685
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Tidskriftsartikel (refereegranskat)abstract
- DNA is a promising material for use in nanotechnology; the persistence length of double stranded DNA gives it a rigid structure in the several nanometer regime and its four letter alphabet enables addressability. We present the construction of a self-assembled DNA-based photonic wire capable of transporting excitation energy over a distance of more than 20 nm. Our results show that it is possible to create two component DNA-based photonic wires capable of long range energy transfer using a straightforward self-assembly approach.
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| 6. |
- Lundberg, Erik, 1981, et al.
(författare)
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Addressable molecular node assembly - high information density DNA nanostructures
- 2008
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Ingår i: Nucleic acids symposium series (2004). - 1746-8272. ; :52, s. 683-684
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Tidskriftsartikel (refereegranskat)abstract
- The inherent self-assembly properties of DNA make it ideal in nanotechnology. We present a fully addressable DNA nanostructure with the smallest possible unit cell, a hexagon with a side-length of only 3.4 nm.(2,3) Using novel three-way oligonucleotides, where each side has a unique double-stranded DNA sequence that can be assigned a specific address, we will build a non-repetitive two-dimensional grid.
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| 7. |
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| 8. |
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| 9. |
- Nordell, Pär, 1978, et al.
(författare)
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Finding at-DNA--kinetic recognition of long adenine-thymine stretches by metal-ligand complexes.
- 2008
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Ingår i: Nucleic acids symposium series (2004). - 1746-8272. ; :52, s. 131-132
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Tidskriftsartikel (refereegranskat)abstract
- High selectivity for long AT sequences can be attained by kinetically controlled DNA threading intercalation by binuclear ruthenium(II) complexes. The rate of intercalation is strongly correlated to the number of consecutive AT basepairs, being up to 2500 times faster with an AT polymer compared to mixed-sequence DNA.
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| 10. |
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