| 1. |
- Aiello, M, et al.
(författare)
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Cognitive, Olfactory, and Affective Determinants of Body Weight in Aging Individuals
- 2019
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Ingår i: Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. - : Oxford University Press (OUP). - 1873-5843. ; 34:5, s. 637-647
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Tidskriftsartikel (refereegranskat)abstract
- ObjectiveA complex interplay of factors including cognitive, sensory and affective aspects has been associated in a controversial way with anthropometric measures related to body weight.MethodsHere we propose two studies to investigate whether and how cognitive, olfactory and affective variables resulted associated with body weight during healthy aging. In Study 1, we investigated the cognitive status, the odor identification skills, and the BMI of 209 individuals (50–96 yo). In Study 2 an extensive evaluation of cognitive functions (in particular executive functions and memory), odor threshold, discrimination and identification and affective skills (i.e., depression and anxiety) was performed in a group of 35 healthy, free-living aging individuals (58–85 yo).ResultsIn Study 1, greater BMI was not associated with performance on the odor identification task but was significantly associated with better cognitive skills. In Study 2, we observed that executive functions seemed to favor a successful managing of body weight, and individuals with greater BMI and waist circumference showed significantly better odor discrimination skills. Finally, lower waist circumference (but not BMI) was found significantly associated with greater levels of anxiety.ConclusionsThese results confirm that cognitive, olfactory and affective factors may influence body weight during healthy aging.
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| 2. |
- Backman, Linda, et al.
(författare)
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Monthlong Intubated Patient with Life-Threatening COVID-19 and Cerebral Microbleeds Suffers Only Mild Cognitive Sequelae at 8-Month Follow-up : A Case Report
- 2022
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Ingår i: Archives of clinical neuropsychology. - : Oxford University Press (OUP). - 0887-6177 .- 1873-5843. ; 37:2, s. 531-543
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Tidskriftsartikel (refereegranskat)abstract
- Objective: To elaborate on possible cognitive sequelae related to COVID-19, associated cerebrovascular injuries as well as the general consequences from intensive care. COVID-19 is known to have several, serious CNS-related consequences, but neuropsychological studies of severe COVID-19 are still rare.Methods: M., a 45-year-old man, who survived a severe COVID-19 disease course including Acute Respiratory Distress Syndrome (ARDS), cerebral microbleeds, and 35 days of mechanical ventilation, is described. We elaborate on M’s recovery and rehabilitation process from onset to the 8-month follow-up. The cognitive functions were evaluated with a comprehensive screening battery at 4 weeks after extubation and at the 8-month follow-up.Results: Following extubation, M. was delirious, reported visual hallucinations, and had severe sleeping difficulties. At about 3 months after COVID-19 onset, M. showed mild to moderate deficits on tests measuring processing speed, working memory, and attention. At assessments at 8 months, M. performed better, with results above average on tests measuring learning, memory, word fluency, and visuospatial functions. Minor deficits were still found regarding logical reasoning, attention, executive functioning, and processing speed. There were no lingering psychiatric symptoms. While M. had returned to a part-time job, he was not able to resume previous work-tasks.Conclusion: This case-study demonstrates possible cognitive deficits after severe COVID-19 and emphasizes the need of a neuropsychological follow-up, with tests sensitive to minor deficits. The main findings of this report provide some support that the long-term prognosis for cognition in severe COVID-19 may be hopeful.
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| 3. |
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| 4. |
- Karilampi, Ulla, et al.
(författare)
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Verbal learning in schizopsychotic outpatients and healthy volunteers as a function of cognitive performance levels
- 2007
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Ingår i: Archives of clinical neuropsychology. - : Oxford University Press (OUP). - 0887-6177 .- 1873-5843. ; 22:2, s. 161-174
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Tidskriftsartikel (refereegranskat)abstract
- OBJECTIVE The aim was to analyze and compare neurocognitive test profiles related to different levels of verbal learning performance among schizopsychotic patients and healthy volunteers. METHOD A single-center patient cohort of 196 participants was compared with an equal-sized volunteer group to form three cognitive subgroups based on the shared verbal learning performance. RESULTS 43.9% of the patients had normal learning ability. Despite this, all patients underperformed the volunteers on all subtests with the exception of working memory, and, for those with high learning ability, even verbal facility. All patients also presented equally poor visuomotor processing speed/efficacy. CONCLUSION A global neurocognitive retardation of speed-related processing in schizophrenia is suggested.
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| 5. |
- Stålhammar, Jacob, 1967, et al.
(författare)
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Neuropsychological Test Performance Among Native and Non-Native Swedes: Second Language Effects. : Neuropsykologisk testprestation hos infödda och icke infödda svensktalande: andraspråkseffekter
- 2022
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Ingår i: Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. - : Oxford University Press (OUP). - 1873-5843. ; 37:4, s. 826-838
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Tidskriftsartikel (refereegranskat)abstract
- We aimed to study second language effects on neuropsychological (NP) test performance.We administered an NP test battery in Swedish to 322 healthy community dwelling participants, recruited through the Gothenburg Pilot phase of the Swedish CArdioPulmonary BioImage Study (SCAPIS Pilot). All participants were conversationally fluent Swedish speakers (237 native, 85 non-native, mean age 61.1years). We compared the NP scores of native and non-native participants. We also investigated the influence of (a) age of arrival to Sweden, (b) majority language family of the birth country, and (c) proficiency in Swedish as assessed with a 30 item Boston naming test (BNT).Native speakers obtained better results on all NP tasks with a verbal component, whereas no significant differences were seen on completely nonverbal tasks (Rey complex figure). For non-native speakers, lower age at arrival to Sweden, arrival from a country where Swedish was also spoken, or arrival from a country with a majority language closer to Swedish, were all linked to better NP scores. Dichotomizing by BNT showed that normally-to-highly proficient non-native speakers obtained better scores.Second language effects may contribute to misclassification of non-native speakers. Assumptions of fluency based on short conversations may be misleading. A proficiency assessment with BNT may improve NP score interpretation among non-native speakers.
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| 6. |
- Sundgren, Mathias, et al.
(författare)
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Cognitive Impairment Has a Strong Relation to Nonsomatic Symptoms of Depression in RelapsingRemitting Multiple Sclerosis
- 2013
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Ingår i: Archives of clinical neuropsychology. - : Oxford University Press (OUP). - 0887-6177 .- 1873-5843. ; 28:2, s. 144-155
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Tidskriftsartikel (refereegranskat)abstract
- It is unclear how cognitive impairment in multiple sclerosis (MS) is influenced by physical disability, fatigue, and depression. Our aim was to identify the strongest clinical predictors for cognitive impairment in relapsing-remitting MS (RRMS) patients. The clinical risk factors included in the analysis were physical disability (EDSS), fatigue (FSS), the somatic and nonsomatic components of depression (BDI), disease progression rate [Multiple Sclerosis Severity Score (MSSS)], and psychotropic medication. Cognitive impairment had a prevalence of 30.5% in patients affecting preferentially attention, executive functions, processing speed and visual perception/organization. MSSS was not associated with cognitive impairment, depression, or fatigue. In regression models, cognitive performance was best predicted by the nonsomatic symptoms of depression alone or in combination with physical disability. Exclusion of patients with any psychotropic medication did not influence the results. Our results underscore the importance of evaluating depressive symptoms when suspecting cognitive impairment in patients with RRMS.
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| 7. |
- Tillman, Carin, et al.
(författare)
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Intellectual deficits in children with ADHD beyond central executive and non-executive functions
- 2009
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Ingår i: Archives of clinical neuropsychology. - : Oxford University Press (OUP). - 0887-6177 .- 1873-5843. ; 24:8, s. 769-782
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Tidskriftsartikel (refereegranskat)abstract
- This study aimed to specify the deficit in intellectual ability in children with attention deficit hyperactivity disorder (ADHD), by studying the mediating role of impairments in central executive function (EF)-related components (working memory, inhibition, sustained attention) and non-EFs (short-term memory and processing speed). Two hundred and thirty children aged 8-11 years from a population-based sample were assigned to either the ADHD group, the clinical comparison group, or the normal comparison group. The results showed that children with ADHD had poorer fluid and crystallized intelligence, relative to both comparison groups. Further, regarding fluid intelligence, these deficits were not fully mediated by, but rather went beyond, poorer functioning on the studied EF-related components and non-EFs. We tentatively interpret these fluid deficits in children with ADHD as representing deficiencies in a general intellectual resource reflecting executive attentional processes. Concerning crystallized ability, in contrast, the deficit signified impairment in the studied cognitive functions, as indicated by the significant full mediation effect.
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| 8. |
- Wehling, Eike, et al.
(författare)
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Unawareness of olfactory dysfunction and its association with cognitive functioning in middle aged and old adults
- 2011
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Ingår i: Archives of clinical neuropsychology. - : Oxford University Press. - 0887-6177 .- 1873-5843. ; 26:3, s. 260-269
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Tidskriftsartikel (refereegranskat)abstract
- The objective of this study was (a) to investigate the accordance of self-reported and objectively assessed olfactory functioning and (b) to compare performance on cognitive tests of individuals unaware of their olfactory dysfunction with individuals aware of their olfactory status. Two hundred forty participants, constituting two age groups, were evaluated with the Scandinavian Odor Identification Test, a question of self-evaluated olfactory function, tests of cognitive function, and a memory questionnaire. The proportion of individuals being unaware of an olfactory dysfunction was high in both middle aged (86%) and old (78%) participants. Performance on neuropsychological tests showed that persons unaware of their olfactory dysfunction performed poorer on tests of verbal learning and memory and attention/processing speed compared to individuals aware of a normal olfactory status as well as individuals aware of their olfactory dysfunction. The clinical relevance of unawareness of olfactory dysfunction, as suggested earlier, needs further investigation and stresses the need of an extensive multi-modal and longitudinal assessment of unawareness of sensory and cognitive function to learn more about the facets of the concept of unawareness.
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| 9. |
- Rahiminejad, Sofia, 1987, et al.
(författare)
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Micromachined Ridge Gap Waveguide and Resonator for Millimeter-Wave Applications
- 2012
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Ingår i: Sensors and Actuators, A: Physical. - : Elsevier BV. - 0924-4247 .- 1873-3069. ; 186, s. 264-269
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Tidskriftsartikel (refereegranskat)abstract
- The ridge gap waveguide is a fundamentally new high-frequency waveguide. It does not need any electrical contact between the split blocks which gives it an advantage compared to the rectangular waveguide which is the standard today. These waveguides are conventionally fabricated by milling, although above 100 GHz milling is not adequate anymore. MEMS technology on the other hand, can offer high-precision fabrication and thus opens the path for new types of high-frequency components. In this paper both a ridge gap waveguide and a ridge gap resonator have been fabricated for the frequencies 220–325 GHz using MEMS technology. Support packages have been designed to enable device measurements. Simulations show that the reflection coefficient for the ridge gap waveguide is below −15 dB between 240 and 340 GHz. Two resonance peaks were measured at the frequencies 234 GHz and 284 GHz for the ridge gap resonator with unloaded Q-values of 336 and 527 respectively. Both the waveguide and resonator have the potential to obtain similar performances as the rectangular waveguide without strict requirement on electrical contact, allowing simplified fabrication and assembly technique.
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