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1.
  • Kim-Lim, P., et al. (författare)
  • Systematic Review of Systemic Corticosteroid Effects on Patch Testing
  • 2022
  • Ingår i: Dermatitis. - : Mary Ann Liebert Inc. - 1710-3568 .- 2162-5220. ; 33:6, s. 405-410
  • Tidskriftsartikel (refereegranskat)abstract
    • Systemic corticosteroids are commonly used as a short-term management option for inflammatory skin conditions, such as contact dermatitis. The purpose of our systematic review was to compare presence and degree of patch test reactions with or without different doses of systemic corticosteroid therapy. The relationship between 20, 30, and 40 mg daily doses of prednisone and retained, diminished, and negated reactions was not linear, whereas the reaction ratings for all patches placed with or without corticosteroid therapy revealed trends toward lower intensity reactions while receiving prednisone (P < 0.0001, chi(2), for all doses of prednisone). Our review provides insight into directions for future studies that examine the effect of corticosteroids on patch testing.
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2.
  • Lejding, Tina, et al. (författare)
  • Analysis of Hexavalent Chromium in Cement Samples From Countries Within and Outside the EU : A Study From the International Contact Dermatitis Research Group
  • 2023
  • Ingår i: Dermatitis : contact, atopic, occupational, drug. - : Mary Ann Liebert Inc. - 1710-3568. ; 34:4, s. 323-328
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Allergic contact dermatitis (ACD) caused by hexavalent chromium (Cr(VI)) is often severe and difficult to treat. The content of Cr(VI) in cement can be reduced by, for example, addition of iron(II) sulfate. Since 2005 the content of Cr(VI) in cement is regulated in the EU Directive 2003/53/EC and must not exceed 2 ppm. Since this regulation came into force, ACD caused by cement has markedly been reduced. Objective: To investigate Cr(VI) and total chromium content in samples of cement from countries within and outside the EU. Methods: The members of the International Contact Dermatitis Research Group (ICDRG) were invited to participate in the study with the aim to collect cement samples from geographically different areas. The content of Cr(VI) in the samples was estimated by the diphenyl carbazide spot test, atomic absorption spectroscopy was used to assess the total chromium content. Results: Forty-five cement samples were analyzed, containing amounts of Cr(VI) from <0.1 to >70 ppm. Twenty-one samples contained >2 ppm Cr(VI), 24 contained less. Four of 17 samples from within the EU contained >2 ppm Cr(VI), that is, higher amounts than stipulated in the EU directive, as compared with 17 samples from countries outside the EU. Conclusion: In countries outside the EU, significantly more cement samples contained >2 ppm Cr(VI).
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