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- Forsgren, Eva, et al.
(författare)
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Bacterial Diseases in Honeybees
- 2018
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Ingår i: Current clinical microbiology reports. - : Springer Science and Business Media LLC. - 2196-5471. ; 5, s. 18-25
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Forskningsöversikt (refereegranskat)abstract
- Purpose of Review American foulbrood (AFB) and European foulbrood (EFB) are widely distributed and highly infectious bacterial diseases of honeybee brood causing colony losses and considerable economic strain on apiculture globally. In this review, we synthesize the most recent discoveries and achievements made towards understanding the pathogenesis and epidemiology of these two bacterial diseases and present current efforts in finding ways to combat them.Recent Findings Advancements in molecular methods, such as next-generation sequencing, have provided high-resolution insight into the epidemiological parameters and factors of virulence for the foulbroods of honeybees.Summary The recently gained detailed knowledge of the diversity, biogeography, and relatedness of strains and sub-types of the causative bacteria of AFB and EFB provides a background to study their epidemiology at many scales. Such information will help provide a more global perspective on honeybee disease epidemiology for an increasingly international beekeeping industry.
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| 2. |
- Leonard, Cory Ann, et al.
(författare)
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Pathogenic Interplay Between Chlamydia trachomatis and Neisseria gonorrhoeae that Influences Management and Control Efforts-More Questions than Answers?
- 2019
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Ingår i: Current Clinical Microbiology Reports. - : Springer. - 2196-5471. ; 6:3, s. 182-191
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Forskningsöversikt (refereegranskat)abstract
- Purpose of Review :To emphasize key gaps in knowledge impacting efforts to control single infection and co-infections with Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG), the most common bacterial sexually transmitted infections (STIs) worldwide.Recent Findings: Clinical and epidemiological studies describe gaps in understanding about female rectal CT infection, screening effectiveness, pelvic inflammatory disease, and influence of the microbiome. For NG, gaps in knowledge include factors increasing incidence in men who have sex with men, correlations between treatment and antibiotic resistance, the role of pharyngeal infection, and microbiome influence. CT/NG co-infections are poorly understood, and adequate models to explore pathophysiological consequences of co-infection urgently needed. The sole existing CT/NG co-infection mouse model showed that CT/NG interactions in vivo modulate host response and NG load/shedding-encouraging further consideration of this model and potential alternatives.Summary: We stress key challenges in controlling these important STIs. Appropriate, quality-assured animal models are essential to improve understanding of the pathogenic interplay in CT/NG co-infections.
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