| 1. |
- Fu, Le, et al.
(författare)
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Enhanced Bacteriostatic Properties of Ti Alloys by Surface Nitriding
- 2023
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Ingår i: Biomedical Materials & Devices. - : Springer Nature. - 2731-4812 .- 2731-4820. ; 1, s. 760-771
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Tidskriftsartikel (refereegranskat)abstract
- Surface nitriding has been widely used to improve the surface physicochemical properties of Ti alloys. However, the currently utilized surface nitriding methods, such as laser nitriding, typically require expensive and complicated instruments, which makes surface nitriding a less cost-effective process. Meanwhile, the antibacterial properties of surface-nitrided Ti alloy implants have not been evaluated. Thereafter, in this study, we were aiming to develop an effective, simple, and cost-effective surface nitriding strategy to enhance the antimicrobial properties of Ti alloy implants. The surface nitriding strategy was realized by wet-chemical etching and thermal treatment at controlled conditions. Results showed that the above surface modification treatments exerted significant effects on the phase composition and morphology of the newly formed phases on the surface of Ti samples. Crystalline TiN and TiO2 formed after treatments. Meanwhile, amorphous nitrides and oxynitride were also presented on the sample surfaces. The surface-modified Ti samples showed a bacterial inhibition effect compared with the non-treated Ti ones, and the bacterial inhibition effect was attributed to the released ammonia species from the surface of Ti samples. The surface modification strategy shows promise to improve the bacteriostatic property of Ti implants in dental and orthopedic fields.
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| 2. |
- Khan, Bangul, et al.
(författare)
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Drawbacks of Artificial Intelligence and Their Potential Solutions in the Healthcare Sector
- 2023
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Ingår i: Biomedical Materials & Devices. - : Springer Science and Business Media LLC. - 2731-4812 .- 2731-4820.
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Tidskriftsartikel (refereegranskat)abstract
- Artificial intelligence (AI) has the potential to make substantial progress toward the goal of making healthcare more personalized, predictive, preventative, and interactive. We believe AI will continue its present path and ultimately become a mature and effective tool for the healthcare sector. Besides this AI-based systems raise concerns regarding data security and privacy. Because health records are important and vulnerable, hackers often target them during data breaches. The absence of standard guidelines for the moral use of AI and ML in healthcare has only served to worsen the situation. There is debate about how far artificial intelligence (AI) may be utilized ethically in healthcare settings since there are no universal guidelines for its use. Therefore, maintaining the confidentiality of medical records is crucial. This study enlightens the possible drawbacks of AI in the implementation of healthcare sector and their solutions to overcome these situations.
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| 3. |
- Sehic, Edina, et al.
(författare)
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Progress in Preclinical Research on Uterus Bioengineering That Utilizes Scaffolds Derived from Decellularized Uterine Tissue
- 2022
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Ingår i: Biomedical Materials & Devices. - : Springer Science and Business Media LLC. - 2731-4812 .- 2731-4820.
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Tidskriftsartikel (refereegranskat)abstract
- During the last decade, uterus transplantation has evolved as the first treatment for absolute uterine factor infertility, caused by absence of a functional uterus. Current challenges in the area of uterus transplantation are organ shortage and side effects of immunosuppression. These hurdles may be solved with novel tissue engineering technologies to produce a uterus from stem cells. For example, the development of patient-specific grafts using a biomaterial together with the patient’s own cells might be utilized for a partial uterus repair therapy or a whole bioengineered uterus might be developed to replace an allogeneic graft in a uterus transplantation setting. During recent years, uterus bioengineering strategies with scaffolds based on decellularized tissue have been particularly assessed. Decellularization protocols were established for both small and large animal models, including the human uterus. Promising in vivo results using such scaffolds to repair a partially injured uterus showed restoration of fertility in rodent models. Scaffold generation protocols and recellularization methodologies including various cell sources are currently being optimized and translated to more clinically relevant injury models in large animals. This review provides a summary of the progress made to date, based on use of decellularized uterine tissue for uterus repair.
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