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1.
  • Breedvelt, Josefien J. F., et al. (författare)
  • An individual participant data meta-analysis of psychological interventions for preventing depression relapse
  • 2024
  • Ingår i: Nature Mental Health. - 2731-6076. ; 2:2, s. 154-163
  • Tidskriftsartikel (refereegranskat)abstract
    • Major depressive disorder is a leading cause of disability worldwide; identifying effective strategies to prevent depression relapse is crucial. This individual participant data meta-analysis addresses whether and for whom psychological interventions can be recommended for relapse prevention of major depressive disorder. One- and two-stage individual patient data meta-analyses were conducted on 14 randomized controlled trials (N = 1,720). The relapse risk over 12 months was substantially lower for those who received a psychological intervention versus treatment as usual, antidepressant medication, or evaluation-only control (hazard ratio, 0.60; 95% confidence interval, 0.48–0.74). The number of previous depression episodes moderated the treatment effect, with psychological interventions demonstrating greater efficacy for patients with three or more previous episodes. Our results suggest that adding psychological interventions to current treatment to prevent depression relapse is recommended. For patients at lower risk of relapse, less-intensive approaches may be indicated.
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3.
  • Seiferth, Caroline, et al. (författare)
  • How to e-mental health : a guideline for researchers and practitioners using digital technology in the context of mental health
  • 2023
  • Ingår i: Nature Mental Health. - : Springer Nature. - 2731-6076. ; 1:8, s. 542-554
  • Tidskriftsartikel (refereegranskat)abstract
    • Despite an exponentially growing number of digital or e-mental health services, methodological guidelines for research and practical implementation are scarce. Here we aim to promote the methodological quality, evidence and long-term implementation of technical innovations in the healthcare system. This expert consensus is based on an iterative Delphi adapted process and provides an overview of the current state-of-the-art guidelines and practical recommendations on the most relevant topics in e-mental health assessment and intervention. Covering three objectives, that is, development, study specifics and intervention evaluation, 11 topics were addressed and co-reviewed by 25 international experts and a think tank in the field of e-mental health. This expert consensus provides a comprehensive essence of scientific knowledge and practical recommendations for e-mental health researchers and clinicians. This way, we aim to enhance the promise of e-mental health: low-threshold access to mental health treatment worldwide.
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