| 1. |
- Gårdhagen, Roland, et al.
(författare)
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Large Eddy Simulation of Flow through a Stenosed Pipe
- 2009
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Ingår i: ASME 2008 Summer Bioengineering Conference, Parts A and B. - : American Society of Mechanical Engineers. - 9780791843215 ; , s. 445-446
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Konferensbidrag (refereegranskat)abstract
- A majority of all deaths in the developed world are related to atherosclerosis, i.e. obstruction of blood vessels caused by growth of the vessel wall. Hemodynamic phenomena, especially wall shear stress, are since several decades thought to influence the risk to develop atherosclerosis; hence simulation of blood flow, either in order to elucidate the relation between the hemodynamic and disease initiation or to study the flow pattern, is an area of intense research [1,2].
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| 2. |
- Lantz, Jonas, et al.
(författare)
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Heating in a Stenosed Coronary Artery With Pulsating Flow and Non-Newtonian Viscosity
- 2009
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Ingår i: ASME 2008 Summer Bioengineering Conference. - : The American Society of Mechanical Engineers (ASME). - 9780791843215 ; , s. 331-332
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Konferensbidrag (refereegranskat)abstract
- Cardiovascular disease is the most prevalent cause of death in the developed countries and most deaths are due to coronary atherosclerosis [1]. During the development of atherosclerosis, several stages can be distinguished including vulnerable plaque. This group of plaque has an inclination for erosion and rupture and is therefore of particular interest. Due to the inflammatory response of vulnerable plaque including an increased metabolism and thereby a locally increased temperature, it is possible to detect such warm cores by intracoronally temperature measurement under some prerequisitions. Temperature differences up to 2.2 K on the surface of carotid plaques have been measured [2], but the relation between plaque vulnerability, inflammatory response, temperature increase and possibility to detection by means of temperature measurement is far from fully perceived.
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| 3. |
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| 4. |
- Renner, Johan, et al.
(författare)
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Subject Specific In-Vivo CFD Estimated Aortic WSS : Comparison Between Manual and Automated Segmentation Methods
- 2009
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Ingår i: ASME 2008 Summer Bioengineering Conference. - : The American Society of Mechanical Engineers (ASME). - 9780791843215 ; , s. 425-426
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Konferensbidrag (refereegranskat)abstract
- When making computational fluid dynamics (CFD) based estimations of wall shear stress (WSS) in the human aorta, medical image converting processes to 3D geometries are important as the result is strongly dependent on the quality of the geometry [1]. The image interpretation process or segmentation can be more or less automated; however in clinical work today the gold standard is to manually interpret the medical image information. This combined magnetic resonance imaging (MRI) and CFD method aims to estimate WSS in human arteries in-vivo as WSS is strongly linked to atherosclerosis [2]. More or less automated segmentation has been used in previous studies but normally based on a stack of 2D individually segmented slices which is combined into a 3D model [3]. The aim of this work is to compare manual 2D and automatic 3D segmentations.
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| 5. |
- Wren, Joakim, et al.
(författare)
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Radiofrequency Thermal Ablation of Liver Tumors : Impact of Large Vessels
- 2009
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Ingår i: ASME 2008 Summer Bioengineering Conference. - : The American Society of Mechanical Engineers (ASME). - 9780791843215 ; , s. 611-612
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Konferensbidrag (refereegranskat)abstract
- Surgical resection is the golden standard for treatment of both primary and metastatic liver tumors, and the method is associated with the highest long-time survival rates [1]. A large number of patients are however not candidates for tumor resection, for example due to un-sufficent hepatic reserve or tumor location relative to large blood vessels. In those cases, an alternative treatment strategy is to heat the tumor(s) to lethal temperatures by means of Radiofrequency (RF) current.
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