| 1. |
- Aurell, Emelie, et al.
(författare)
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Mikroplaster : Redovisning av regeringsuppdrag om källor till mikroplaster och förslag på åtgärder för minskade utsläpp i Sverige
- 2017
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- I augusti 2015 fick Naturvårdsverket i uppdrag från regeringen att identifiera viktigare källor i Sverige till utsläpp av mikroplaster till havet och verka för att reducera utsläppen från dessa källor. I den här rapporten redovisar Naturvårdsverket uppdraget. Vi presenterar resultaten från den första, övergripande kartläggningen av källor till och spridning av mikroplaster i Sverige, en bedömning av vilka av de kartlagda källorna som primärt bör åtgärdas samt vilka steg som behöver tas för att förebygga utsläpp och minska spridning av mikroplaster till hav, sjöar och vattendrag från dessa källor.Förekomsten av mikroplast i den marina miljön har uppmärksammats allt mer under senare år, inte minst på global nivå. Mikroplast är ett samlingsnamn för små, små plastfragment (1 nm till 5 mm). De mikroplaster som hittats i världshaven, men även i sötvattensystem, har olika ursprung. Mikroplast kan bildas oavsiktligt när plastföremål slits och plastpartiklar frigörs, eller när vi inte återanvänder, återvinner eller slänger plastmaterial på rätt sätt utan plasten blir skräp som succesivt bryts ned till mindre och mindre bitar i naturen. Det finns också plast som från början tillverkas som små pellets eller korn.Utgångspunkten för arbetet har varit miljökvalitetsmålen Hav i balans samt levande kust och Levande sjöar och vattendrag samt målet om Giftfri miljö. Reduceradeutsläpp av mikroplaster till hav, sjöar och vattendrag bidrar till att nå dessa mål.Uppdraget har genomförts av Naturvårdsverket i samarbete med Havs- och vattenmyndigheten, andra berörda myndigheter, samt med deltagande av berörda organisationer och andra intressenter mellan augusti 2015 och maj 2017. Slutsatserna är Naturvårdsverkets egna.
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| 2. |
- Blomberg, Oscar, et al.
(författare)
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Adaptation of a guided low-intensity behavioral activation intervention for people with dementia in Sweden : a qualitative study exploring the needs and preferences of key stakeholders
- 2024
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Ingår i: BMC Geriatrics. - : Springer. - 1471-2318. ; 24:113
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Tidskriftsartikel (refereegranskat)abstract
- BackgroundDespite depression being prevalent in people with dementia, contributing to negative health outcomes and placing increased burden on individuals and family members, access to psychological interventions is limited. A potential solution is guided low-intensity behavioral activation, supported by informal caregivers and guided by healthcare professionals. However, it is necessary to adapt interventions to meet the needs and preferences of key stakeholders to enhance acceptability and relevance. Study objectives were to: (1) explore needs and preferences concerning the content and delivery model of the guided low-intensity behavioral activation intervention; and (2) adapt the intervention to ensure cultural appropriateness, relevancy, and acceptability to people with dementia and their caregivers in Sweden.MethodsSemi-structured interviews and focus group discussions were conducted with key stakeholders, including healthcare professionals (n = 18), community stakeholders (n = 7), people with dementia (n = 8), and informal caregivers (n = 19). A draft of the written low-intensity behavioral activation intervention and a description of the proposed intervention delivery model were provided to participants. Open-ended questions explored the perceived relevance of the intervention, alongside needs and preferences concerning content and delivery. A manifest content analysis approach was adopted.ResultsContent analysis resulted in three categories: Content, Delivery procedures, and Illness trajectory. Results highlighted a need to consider the intervention Content via increased cultural adaptation to the Swedish context, and increasing the inclusiveness of intervention content. Delivery procedures were identified as needing to be flexible given the unpredictable nature of caring for people with dementia, with the provision of additional guidance to informal caregivers supporting the intervention. Illness trajectory was viewed as essential to consider, with the intervention regarded as suitable for those early in the dementia trajectory, alongside a need to reduce workbook text to minimize burden given dementia symptomology.ConclusionsThe intervention and proposed delivery model were generally well received by all stakeholders. We were able to identify key adaptations to enhance cultural appropriateness, relevancy, and acceptability for a currently neglected population. Results will inform a feasibility study to explore the feasibility and acceptability of the intervention and study procedures to inform the design of a future superiority randomized controlled trial.
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| 3. |
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| 5. |
- Hammar, Linus, et al.
(författare)
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Symphony : Integrerat planeringsstöd för statlig havsplanering utifrån en ekosystemansats
- 2018
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- Symphony beräknar den kumulativa, sammanlagda, miljöpåverkan i havet. Beräkningarna baseras på en transparent vetenskaplig metod som framförallt baseras på nationellt täckande kartor över ekologiska värden och belastningar från mänskliga verksamheter.Genom Symphony kan havsplanernas effekt på miljöpåverkan bedömas och resultatet påverkar havsplanernas utformning. Denna rapport är framtagen för havsplaneringens samrådsskede 2018.Mycket nyttigt i bilagornaDu kan tända och släcka lager i den första kartan i bilaga 1 och 2 för att utforska materialet. Då behöver du en pdf-läsare som stödjer den funktionen, till exempel Adobe Reader eller Foxit Reader.Till rapporten hör flera bilagorMetadata visar båda kartorna från de olika påverkanslagerna och beskriver hur de data som påverkanslagerna representerar har tagits fram och skalats.Gröna kartan visar alla ekologiska värden som ligger till grund för kartorna.Känslighetsmatrisen visar hur de ekologiska värdena påverkas av belastningarna.Nuläget utan havsplan (bilagor 4 abc)Nuläget med havsplan, alltså havsplanens påverkan om den hade implementerats direkt (bilagor 5 abc)Utblick på hur miljöpåverkan utvecklats till år 2030 utan havsplan (bilagor 6 abc)
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| 6. |
- Lundqvist, Anders, et al.
(författare)
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Altering the biochemical state of individual cultured cells and organelles with ultramicroelectrodes.
- 1998
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - Univ Goteborg, Dept Chem, SE-41296 Goteborg, Sweden. Sahlgrens Univ Hosp, Inst Clin Neurosci, Dept Neurol, SE-41345 Goteborg, Sweden. : NATL ACAD SCIENCES. - 0027-8424 .- 1091-6490. ; 95:18, s. 10356-60
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Tidskriftsartikel (refereegranskat)abstract
- We describe an efficient technique for the selective chemical and biological manipulation of the contents of individual cells. This technique is based on the electric-field-induced permeabilization (electroporation) in biological membranes using a low-voltage pulse generator and microelectrodes. A spatially highly focused electric field allows introduction of polar cell-impermeant solutes such as fluorescent dyes, fluorogenic reagents, and DNA into single cells. The high spatial resolution of the technique allows for design of, for example, cellular network constructions in which cells in close contact with each other can be made to possess different biochemical, biophysical, and morphological properties. Fluorescein, and fluo-3 (a calcium-sensitive fluorophore), are electroporated into the soma of cultured single progenitor cells derived from adult rat hippocampus. Fluo-3 also is introduced into individual submicrometer diameter processes of thapsigargin-treated progenitor cells, and a plasmid vector cDNA construct (pRAY 1), expressing the green fluorescent protein, is electroporated into cultured single COS 7 cells. At high electric field strengths, observations of dye-transfer into organelles are proposed.
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| 7. |
- Skog, Frida, 1979-
(författare)
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The impact of family composition on adult earnings
- 2016
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- This thesis addresses to what extent childhood family composition – the number of siblings and whether the parents live together, or whether there are non-parental adults and/or half-siblings in the household or not – contributes to variations in adult earnings. The theoretical perspective suggests that resources mediate the effect. While research has shown that siblings, as well as divorce and remarriage, are negatively linked to child outcomes, there are inconsistencies in previous literature. There has been debate over the unconfoundedness of previous studies, something that is handled here by analyzing large sets of representative data using a robust parameter. The longitudinal dataset used is based on Swedish administrative data and the cohorts analyzed are born in the beginning of the 1970s. The data structure is well suited for the assumptions underlying the semi-parametric method propensity score matching.The findings show that family size impacts on adult earnings. However, this is not always of concern. For example, no effect of siblings is found in affluent families, and if siblings are closely spaced this results in better outcomes for children. Divorce and remarriage do not seem to lower the future earnings of children. Thus, this thesis shows that some of the most well-established patterns in the sociology of the family, namely the link between number of siblings and adult earnings, and between divorce/family re-formation and adult earnings, can be broken by resources.
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| 8. |
- Strömberg Celind, Frida, 1980, et al.
(författare)
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Higher parental education was associated with better asthma control
- 2019
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Ingår i: Acta Paediatrica. - : Wiley. - 0803-5253 .- 1651-2227. ; 108:5, s. 920-926
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Tidskriftsartikel (refereegranskat)abstract
- Inhaled corticosteroids have resulted in the improved control of asthma and a reduced need for hospitalisation. This study aimed to examine the prevalence of uncontrolled asthma and factors that affect asthma control.The data came from a longitudinal cohort study of children. The parents answered questionnaires from age 6months to 12years. The response rate at age 12years was 76% (3637/4777) and doctor-diagnosed asthma was reported in 6.4% (n=233). Asthma control was examined with the Asthma Control Test (ACT), where scores below 20 denote uncontrolled asthma.Of the children with asthma at age 12 years, 15% had an ACT value below 20, that is uncontrolled asthma. Independent risk factors for uncontrolled asthma were wheeze triggered by exercise (adjusted OR, aOR 5.6; 1.9-16.6), cat at home (aOR 3.5; 1.2-10.0) and current doctor-diagnosed rhinitis (aOR 2.8; 95% CI 1.1-7.0). A higher education in the parents reduced the risk of uncontrolled asthma (aOR 0.3; 95% CI 0.1-0.8). Only six children (i.e. 2.6%) reported hospitalisation due to asthma during the last year.Of the children with asthma, 15% had uncontrolled asthma. Higher education in the parents was associated with better asthma control in the children.
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| 9. |
- Svedin, Frida, Doktorand, et al.
(författare)
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Adapting a guided low-intensity behavioural activation intervention for people with dementia and depression in the Swedish healthcare context (INVOLVERA) : a study protocol using codesign and participatory action research.
- 2021
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Ingår i: BMJ Open. - : BMJ. - 2044-6055. ; 11:7
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Tidskriftsartikel (refereegranskat)abstract
- INTRODUCTION: Dementia is a worldwide health concern with incident rates continuing to increase. While depression prevalence is high in people with dementia and psychological interventions such as cognitive behavioural therapy (CBT) are effective, access to psychological interventions remains limited. Reliance on traditional CBT for people with dementia and depression may present difficulties given it is a complex psychological approach, costly to deliver, and professional training time is lengthy. An alternative approach is behavioural activation (BA), a simpler psychological intervention for depression. The present study seeks to work with people with dementia, informal caregivers, community stakeholders, and healthcare professionals, to adapt a guided low-intensity BA intervention for people with dementia and depression, while maximising implementation potential within the Swedish healthcare context.METHODS AND ANALYSIS: A mixed methods study using codesign, principles from participatory action research (PAR) and normalisation process theory to facilitate the cultural relevance, appropriateness and implementation potential of the intervention. The study will consist of four iterative PAR phases, using focus groups with healthcare professionals and community stakeholders, and semi-structured interviews with people with dementia and informal caregivers. A content analysis approach will be adopted to analyse the transcribed focus groups and semi-structured interviews recordings.ETHICS AND DISSEMINATION: The study will be conducted in accordance with the Declaration of Helsinki and data handled according to General Data Protection Regulation. Written informed consent will be obtained from all study participants. In accordance with the Swedish Health and Medical Services Act, capacity to consent will be examined by a member of the research team. Ethical approval has been obtained from the Swedish Ethical Review Authority (Dnr: 2020-05542 and Dnr: 2021-00925). Findings will be published in an open access peer-reviewed journal, presented at academic conferences, and disseminated among lay and healthcare professional audiences.
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