| 1. |
- Ali, Akbar, et al.
(författare)
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Silver-chitosan nanobiocomposite as urea biosensor
- 2014
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Ingår i: Optoelectronics and Advanced Materials Rapid Communications. - : NATL INST OPTOELECTRONICS. - 1842-6573 .- 2065-3824. ; 8:11-12, s. 1238-1242
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Tidskriftsartikel (refereegranskat)abstract
- Silver nanoparticles (Ag NPs) were synthesized by aqueous chemical growth technique. The above mentioned synthesized materials were characterized by applying scanning electron microscope (SEM) and X-ray diffraction for confirmation of morphological analysis, compositional purity, and crystalline property and emission characteristics as well. In order to fabricate the urea biosensor (potentiometric), a solution of deionized water and chitosan was prepared having Ag NPs. The said solution was dropped on the glass fiber filter having diameter of 2 cm. A wire of copper having thickness of approximately 500 pm was used for the voltage signal to pull out from the said working nanoparticles (NPs). To improve the strength, sensitivity and the quality of the potentiometric urea biosensor, a specific functional surface of Ag NPs was attained by electrostatic restrained of an enzyme (urease) onto the chitosan-Ag (a nanobiocomposite). The potentiometric reaction was measured via electrochemical detection technique. The potentiometric urea biosensor illustrates significant sensibility at room temperature with approximate to 42 mV as per span. Furthermore, the said biosensor showed an appropriate stable response within 7 sec.
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| 2. |
- Fakhar-E-Alam, M., et al.
(författare)
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Anticancer effects of nanometallic oxides and their ligands with photosensitizers in osteosarcoma cells
- 2015
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Ingår i: Journal of Optoelectronics and Advanced Materials. - : NATL INST OPTOELECTRONICS. - 1454-4164 .- 1841-7132. ; 17:11-12, s. 1808-1815
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Tidskriftsartikel (refereegranskat)abstract
- We studied the cytotoxic effects in Osteosarcoma (U2OS) cells to different nanosized metallic oxides e.g. zinc oxide nanowires (ZnO-NRs), manganese di-oxide nanowires (MnO2 NWs), ferric oxide nanoparticles (Fe2O3 NPs) individually and their connplexed forms with photosensitizers photofrin (R), 5-Aminolevulinic acid (5-ALA), and protoporphyrin IX (Pp IX). Cellular toxicity was assayed by cellular morphology, reactive oxygen species (ROS) detection, MTT assay under ultraviolet (UV), visible light and laser exposed conditions. Prominent cell death with above cited nanomaterials in their complexed forms with Photosensitizer was observed in labeled U2OS cells. This cell death might be due to their synergetic effect via the release of singlet oxygen species in Osteosarcoma cells showing their anticancer-cell effects.
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