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- Castro-González, A., et al.
(författare)
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The K2-OjOS Project*New and revisited planets and candidates in K2 campaigns 5, 16, & 18
- 2022
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Ingår i: Monthly Notices of the Royal Astronomical Society. - : Oxford University Press (OUP). - 0035-8711 .- 1365-2966. ; 509:1, s. 1075-1095
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Tidskriftsartikel (refereegranskat)abstract
- We present the first results of K2-OjOS, a collaborative project between professional and amateur astronomers primarily aimed to detect, characterize, and validate new extrasolar planets. For this work, 10 amateur astronomers looked for planetary signals by visually inspecting the 20 427 light curves of K2 campaign 18 (C18). They found 42 planet candidates, of which 18 are new detections and 24 had been detected in the overlapping C5 by previous works. We used archival photometric and spectroscopic observations, as well as new high-spatial resolution images in order to carry out a complete analysis of the candidates found, including a homogeneous characterization of the host stars, transit modelling, search for transit timing variations and statistical validation. As a result, we report four new planets (K2-355 b, K2-356 b, K2-357 b, and K2-358 b) and 14 planet candidates. Besides, we refine the transit ephemeris of the previously published planets and candidates by modelling C5, C16 (when available) and C18 photometric data jointly, largely improving the period and mid-transit time precision. Regarding individual systems, we highlight the new planet K2-356 b and candidate EPIC 211537087.02 being near a 2:1 period commensurability, the detection of significant TTVs in the bright star K2-184 (V = 10.35), the location of K2-103 b inside the habitable zone according to optimistic models, the detection of a new single transit in the known system K2-274, and the disposition reassignment of K2-120 b, which we consider as a planet candidate as the origin of the signal cannot be ascertained.
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- Dahlman-Höglund, Anna, 1964, et al.
(författare)
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Exposure to parvalbumin allergen and aerosols among herring processing workers.
- 2013
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Ingår i: The Annals of occupational hygiene. - : Oxford University Press (OUP). - 1475-3162. ; 57:8, s. 1020-9
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Tidskriftsartikel (refereegranskat)abstract
- There are increasing reports of allergies and respiratory symptoms among workers in the fish processing industry, coinciding with an increasing use of high-pressure water in the processing plants. However, few studies have measured exposure in these work environments.
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- Gomez-Garrido, Jessica, et al.
(författare)
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Chromosome-level genome assembly of Lilford's wall lizard, Podarcis lilfordi (Günther, 1874) from the Balearic Islands (Spain)
- 2023
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Ingår i: DNA Research. - 1340-2838. ; 30:3
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Tidskriftsartikel (refereegranskat)abstract
- The Mediterranean lizard Podarcis lilfordi is an emblematic species of the Balearic Islands. The extensive phenotypic diversity among extant isolated populations makes the species a great insular model system for eco-evolutionary studies, as well as a challenging target for conservation management plans. Here we report the first high-quality chromosome-level assembly and annotation of the P. lilfordi genome, along with its mitogenome, based on a mixed sequencing strategy (10X Genomics linked reads, Oxford Nanopore Technologies long reads and Hi-C scaffolding) coupled with extensive transcriptomic data (Illumina and PacBio). The genome assembly (1.5 Gb) is highly contiguous (N50 = 90 Mb) and complete, with 99% of the sequence assigned to candidate chromosomal sequences and >97% gene completeness. We annotated a total of 25,663 protein-coding genes translating into 38,615 proteins. Comparison to the genome of the related species Podarcis muralis revealed substantial similarity in genome size, annotation metrics, repeat content, and a strong collinearity, despite their evolutionary distance (∼18-20 MYA). This genome expands the repertoire of available reptilian genomes and will facilitate the exploration of the molecular and evolutionary processes underlying the extraordinary phenotypic diversity of this insular species, while providing a critical resource for conservation genomics.
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- Klionsky, Daniel J., et al.
(författare)
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Guidelines for the use and interpretation of assays for monitoring autophagy
- 2012
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Ingår i: Autophagy. - : Informa UK Limited. - 1554-8635 .- 1554-8627. ; 8:4, s. 445-544
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Forskningsöversikt (refereegranskat)abstract
- In 2008 we published the first set of guidelines for standardizing research in autophagy. Since then, research on this topic has continued to accelerate, and many new scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Accordingly, it is important to update these guidelines for monitoring autophagy in different organisms. Various reviews have described the range of assays that have been used for this purpose. Nevertheless, there continues to be confusion regarding acceptable methods to measure autophagy, especially in multicellular eukaryotes. A key point that needs to be emphasized is that there is a difference between measurements that monitor the numbers or volume of autophagic elements (e.g., autophagosomes or autolysosomes) at any stage of the autophagic process vs. those that measure flux through the autophagy pathway (i.e., the complete process); thus, a block in macroautophagy that results in autophagosome accumulation needs to be differentiated from stimuli that result in increased autophagic activity, defined as increased autophagy induction coupled with increased delivery to, and degradation within, lysosomes (in most higher eukaryotes and some protists such as Dictyostelium) or the vacuole (in plants and fungi). In other words, it is especially important that investigators new to the field understand that the appearance of more autophagosomes does not necessarily equate with more autophagy. In fact, in many cases, autophagosomes accumulate because of a block in trafficking to lysosomes without a concomitant change in autophagosome biogenesis, whereas an increase in autolysosomes may reflect a reduction in degradative activity. Here, we present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes. These guidelines are not meant to be a formulaic set of rules, because the appropriate assays depend in part on the question being asked and the system being used. In addition, we emphasize that no individual assay is guaranteed to be the most appropriate one in every situation, and we strongly recommend the use of multiple assays to monitor autophagy. In these guidelines, we consider these various methods of assessing autophagy and what information can, or cannot, be obtained from them. Finally, by discussing the merits and limits of particular autophagy assays, we hope to encourage technical innovation in the field.
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- Palomino-Ángel, Sebastián, et al.
(författare)
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Analysis of Floodplain Dynamics in the Atrato River Colombia Using SAR Interferometry
- 2019
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Ingår i: Water. - : MDPI AG. - 2073-4441. ; 11:5
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Tidskriftsartikel (refereegranskat)abstract
- Floodplain water flows have large volumetric flowrates and high complexity in space and time that are difficult to understand using water level gauges. We here analyze the spatial and temporal fluctuations of surface water flows in the floodplain of the Atrato River, Colombia, in order to evaluate their hydrological connectivity. The basin is one of the rainiest areas of the world with wetland ecosystems threatened by the expansion of agriculture and mining activities. We used 16 Differential Interferometric Synthetic Aperture Radars (DInSAR) phase observations from the ALOS-PALSAR L-band instrument acquired between 2008-2010 to characterize the flow of surface water. We were able to observe water level change in vegetated wetland areas and identify flooding patterns. In the lower basin, flow patterns are conditioned by fluctuations in the levels of the main river channel, whereas in the middle basin, topography and superficial channels strongly influence the flow and connectivity. We found that the variations in water level in a station on the main channel 87 km upstream explained more than 56% of the variations in water level in the floodplain. This result shows that, despite current expansion of agriculture and mining activities, there remain significant hydrological connectivity between wetlands and the Atrato River. This study demonstrates the use of DInSAR for a spatially comprehensive monitoring of the Atrato River basin hydrology. For the first time, we identified the spatiotemporal patterns of surface water flow of the region. We recommend these observations serve as a baseline to monitor the potential impact of ongoing human activities on surface water flows across the Atrato River basin.
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