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Sökning: WFRF:(Afshari Alireza)

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1.
  • Lozano, Rafael, et al. (författare)
  • Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017
  • 2018
  • Ingår i: The Lancet. - : Elsevier. - 1474-547X .- 0140-6736. ; 392:10159, s. 2091-2138
  • Tidskriftsartikel (refereegranskat)abstract
    • Background: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of “leaving no one behind”, it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017), we measured progress on 41 of 52 health-related SDG indicators and estimated the health-related SDG index for 195 countries and territories for the period 1990–2017, projected indicators to 2030, and analysed global attainment. Methods: We measured progress on 41 health-related SDG indicators from 1990 to 2017, an increase of four indicators since GBD 2016 (new indicators were health worker density, sexual violence by non-intimate partners, population census status, and prevalence of physical and sexual violence [reported separately]). We also improved the measurement of several previously reported indicators. We constructed national-level estimates and, for a subset of health-related SDGs, examined indicator-level differences by sex and Socio-demographic Index (SDI) quintile. We also did subnational assessments of performance for selected countries. To construct the health-related SDG index, we transformed the value for each indicator on a scale of 0–100, with 0 as the 2·5th percentile and 100 as the 97·5th percentile of 1000 draws calculated from 1990 to 2030, and took the geometric mean of the scaled indicators by target. To generate projections through 2030, we used a forecasting framework that drew estimates from the broader GBD study and used weighted averages of indicator-specific and country-specific annualised rates of change from 1990 to 2017 to inform future estimates. We assessed attainment of indicators with defined targets in two ways: first, using mean values projected for 2030, and then using the probability of attainment in 2030 calculated from 1000 draws. We also did a global attainment analysis of the feasibility of attaining SDG targets on the basis of past trends. Using 2015 global averages of indicators with defined SDG targets, we calculated the global annualised rates of change required from 2015 to 2030 to meet these targets, and then identified in what percentiles the required global annualised rates of change fell in the distribution of country-level rates of change from 1990 to 2015. We took the mean of these global percentile values across indicators and applied the past rate of change at this mean global percentile to all health-related SDG indicators, irrespective of target definition, to estimate the equivalent 2030 global average value and percentage change from 2015 to 2030 for each indicator. Findings: The global median health-related SDG index in 2017 was 59·4 (IQR 35·4–67·3), ranging from a low of 11·6 (95% uncertainty interval 9·6–14·0) to a high of 84·9 (83·1–86·7). SDG index values in countries assessed at the subnational level varied substantially, particularly in China and India, although scores in Japan and the UK were more homogeneous. Indicators also varied by SDI quintile and sex, with males having worse outcomes than females for non-communicable disease (NCD) mortality, alcohol use, and smoking, among others. Most countries were projected to have a higher health-related SDG index in 2030 than in 2017, while country-level probabilities of attainment by 2030 varied widely by indicator. Under-5 mortality, neonatal mortality, maternal mortality ratio, and malaria indicators had the most countries with at least 95% probability of target attainment. Other indicators, including NCD mortality and suicide mortality, had no countries projected to meet corresponding SDG targets on the basis of projected mean values for 2030 but showed some probability of attainment by 2030. For some indicators, including child malnutrition, several infectious diseases, and most violence measures, the annualised rates of change required to meet SDG targets far exceeded the pace of progress achieved by any country in the recent past. We found that applying the mean global annualised rate of change to indicators without defined targets would equate to about 19% and 22% reductions in global smoking and alcohol consumption, respectively; a 47% decline in adolescent birth rates; and a more than 85% increase in health worker density per 1000 population by 2030. Interpretation: The GBD study offers a unique, robust platform for monitoring the health-related SDGs across demographic and geographic dimensions. Our findings underscore the importance of increased collection and analysis of disaggregated data and highlight where more deliberate design or targeting of interventions could accelerate progress in attaining the SDGs. Current projections show that many health-related SDG indicators, NCDs, NCD-related risks, and violence-related indicators will require a concerted shift away from what might have driven past gains—curative interventions in the case of NCDs—towards multisectoral, prevention-oriented policy action and investments to achieve SDG aims. Notably, several targets, if they are to be met by 2030, demand a pace of progress that no country has achieved in the recent past. The future is fundamentally uncertain, and no model can fully predict what breakthroughs or events might alter the course of the SDGs. What is clear is that our actions—or inaction—today will ultimately dictate how close the world, collectively, can get to leaving no one behind by 2030.
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2.
  • Abbafati, Cristiana, et al. (författare)
  • 2020
  • Tidskriftsartikel (refereegranskat)
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3.
  • Afshari, Alireza, 1956 (författare)
  • Determination of VOC Emissions from Surface Coatings by Environmental Test Chamber Measurements
  • 1999
  • Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
    • The emitting properties of different building materials are obtained by measurements in environmental chambers of a few established designs. In order to interpret the results from the measurements and to predict the influence on the indoor environment, it is necessary to have a good understanding of the parameters governing the emission process. The aim of this thesis is to contribute to this understanding by focusing on the process of emission of chemicals from building materials and on the influence of a number of parameters governing the process. In emission studies reported in the literature, few investigations deal with the comparison of the VOC emission rates obtained by measurements in different test chambers. In the present study, a 1m3-chamber, a CLIMPAQ and a FLEC were used for measurement of the concentrations of various compounds from surface coatings. The study focuses on parameters which could be considered to have a substantial influence on the emission rates, or which do not appear to have been thoroughly studied previously. Interest has mainly been focused on the influence of air velocity, airflow rate and sorption on the emission rate, when other parameters have been maintained constant. It was found that during the first 24 hours, by varying the airflow rate under given test conditions in a test chamber, a number of physical parameters have a direct influence on the emission process. From the start of the test until steady state has been reached, the measured concentration variations may be divided into three different phases. The results from measurements showed that the higher the airflow rates, the faster a steady state was attained. Furthermore, all the selected substances did not reach steady state at the same time during the experiments. The effect of the air velocity above the surface on the emission of VOCs was studied in the three mentioned environmental chambers. It was found that the emission rates of the compounds at 22, 23 and 24 hours after the start of the test systematically increase with increasing air velocity. It was possible to determine the magnitude of increase to 10-20%. However, it was difficult to determine the exact level of increase of the emission rate, due to the uncertainty of the measurements and the low levels of increase. Finally, the characterisation of adsorption of VOCs on the inside of the empty chambers has been studied. The experimental studies for all three chambers show that the sorption of substances in the 1 m3-chamber was slightly lower than in the FLEC. The CLIMPAQ shows a larger capacity of sorption with material specimens than without material specimens. This indicates that the gases emitted from painted plates adsorb again onto the test materials.
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4.
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5.
  • Afshari, Alireza, 1956, et al. (författare)
  • Impact of Ventilation Rate, Ozone and Limonene on Perceived Air Quality in Offices
  • 2002
  • Ingår i: Proceedings of the Indoor Air 2002 Conference.
  • Konferensbidrag (refereegranskat)abstract
    • The objective of this study has been to clarify to what extent ozone (03) and 03 !limonene in interaction with surface materials has an impact on the indoor air quality in typical low-polluting offices at various, realistic air change rates. Changes of environmental conditions were performed seven days before the chemical sampling. Organic compounds were collected on Tenax TA adsorbent tubes and the samples were analysed by gas chromatography with flame ionisation and mass selective detectors. The concentration of Total Volatile Organic Compounds were asexpected found to be inversely proportional to air change rates. Aldehydes and organic acids werefound at increased levels when the air change rate was decreased from 1.0 h1 to 0.3 h1. Increased ventilation rate to 3.0 h1 did not induce additional changes in the chemical composition of aldehydes and organic acids. The fractions of aldehydes and organic acids relative to nonreactive alkanes indicated that chemical transformation in the indoor environment indeed took place; however, it could not be clearly specified whether the chemical changes were of homogeneous or heterogeneous character. The effects of 03 and 03 /limonene in interaction with surface materials in the offices over seven weeks showed different reaction pattems depending material and treatment.
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7.
  • Afshari, Alireza, 1956, et al. (författare)
  • Naborøg og overførsel af partielforurening
  • 2010
  • Ingår i: HVAC - Magasin for klima- og energiteknik, miljø, bygningsinstalltioner & -Netværk. ; 1:2010, s. 24-30
  • Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)
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8.
  • Afshari, Alireza, 1956, et al. (författare)
  • Quantification of ultrafine particles from second-hand tobacco smoke infiltration
  • 2010
  • Ingår i: Proceedings of the CLIMA 2010 Conference: 10th REHVA World Congress 'Sustainable Energy use in Buildings', 8 pages.
  • Konferensbidrag (övrigt vetenskapligt/konstnärligt)abstract
    • This paper presents some of the results of a second-hand tobacco smoke intervention studycarried out in 19 flats in four different buildings. Two of the investigated buildings were nonrenovatedand two others were renovated. The aim of the study was to quantify infiltration ofultrafine particles from a smoker's flat into a non-smoker's flat. In addition, several tests werecarried out to describe some solutions for reduction of particle concentrations in the smoker'sflat and the non-smoker's flat. The air change rates and the indoor particle concentrationswere measured continuously during the measuring periods. The particle sources (particlegenerating activities) were cigarette-burning in the un-occupied buildings and candle-burningin the occupied buildings. Reductions of the concentration of ultrafine particles using aircleaning devices were studied. Results showed that the transfer of ultrafine particles wasabout 9% when the source flat was located below the receiving flat, whereas the transfer was1-2% when the source flat was on the same floor as, or above, the receiving flat.
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9.
  • Bräuner, Elvira Vaclavik, et al. (författare)
  • Indoor particles affect vascular function in the aged: an air filtration-based intervention study.
  • 2008
  • Ingår i: American journal of respiratory and critical care medicine. - 1535-4970. ; 177:4, s. 419-25
  • Tidskriftsartikel (refereegranskat)abstract
    • RATIONALE: Exposure to particulate matter is associated with risk of cardiovascular events, possibly through endothelial dysfunction, and indoor air may be most important. OBJECTIVES: We investigated effects of controlled exposure to indoor air particles on microvascular function (MVF) as the primary endpoint and biomarkers of inflammation and oxidative stress as secondary endpoints in a healthy elderly population. METHODS: A total of 21 nonsmoking couples participated in a randomized, double-blind, crossover study with two consecutive 48-hour exposures to either particle-filtered or nonfiltered air (2,533-4,058 and 7,718-12,988 particles/cm(3), respectively) in their homes. MEASUREMENTS AND MAIN RESULTS: MVF was assessed noninvasively by measuring digital peripheral artery tone after arm ischemia. Secondary endpoints included hemoglobin, red blood cells, platelet count, coagulation factors, P-selectin, plasma amyloid A, C-reactive protein, fibrinogen, IL-6, tumor necrosis factor-alpha, protein oxidation measured as 2-aminoadipic semialdehyde in plasma, urinary 8-iso-prostaglandin F(2alpha), and blood pressure. Indoor air filtration significantly improved MVF by 8.1% (95% confidence interval, 0.4-16.3%), and the particulate matter (diameter < 2.5 mum) mass of the indoor particles was more important than the total number concentration (10-700 nm) for these effects. MVF was significantly associated with personal exposure to iron, potassium, copper, zinc, arsenic, and lead in the fine fraction. After Bonferroni correction, none of the secondary biomarkers changed significantly. CONCLUSIONS: Reduction of particle exposure by filtration of recirculated indoor air for only 48 hours improved MVF in healthy elderly citizens, suggesting that this may be a feasible way of reducing the risk of cardiovascular disease.
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10.
  • Enze, Tian, et al. (författare)
  • Airborne Particles removal by Negative Ions Generated in Ambient Air and Inert Gas
  • 2017
  • Ingår i: In: Proceedings of the 10<sup>th</sup> International Symposium on Heating, Ventilation and Air Conditioning – ISHVAC 2017. 19-22 2017; Jinan, China.
  • Konferensbidrag (refereegranskat)abstract
    • Airborne particles can be removed by air ions in enclosed environment, but the main drawback of this method is the formation of harmful by-products such as ozone (O3). In this study, we use ambient air and inert gas, including argon (Ar) and Nitrogen (N2) to generate negative ions respectively, and then release those ions into an enclosed chamber with ambient air. We then investigated the particle concentration decay rates and O3 concentration increase in the chamber. We found that the particle concentration decay rates were 0.343 min-1, 0.209 min-1 and 0.274 min-1 when ions were generated in ambient air, Ar and N2 respectively. The ozone concentration does not show a marked increase when using either ambient air or inert gas (Ar and N2) to generate ions. Since the temperature and humidity of ambient air may influence the ozone generation during ionizing, further study should be investigated.
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