| 1. |
- Nahi, Hareth, et al.
(författare)
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An investigation into whether deletions in 9p reflect prognosis in adult precursor B-cell acute lymphoblastic leukemia : a multi-center study of 381 patients
- 2008
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Ingår i: Haematologica. - Pavia : Ferrata Storti Foundation (Haematologica). - 1592-8721 .- 0390-6078. ; 93:11, s. 8-1734
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Tidskriftsartikel (refereegranskat)abstract
- In acute lymphoblastic leukemia, besides age and white cell count at diagnosis, the cytogenetic abnormalities t(9;22)/BCR-ABL and t(4;11)/MLL-AF4 are important prognostic markers and are often included in the treatment stratification of patients with adult acute lymphoblastic leukemia. Deletions in 9p are seen in about 9% of cases of adult acute lymphoblastic leukemia, but their prognostic impact has been controversial. Cytogenetic data from 381 patients diagnosed with B-precursor acute lymphoblastic leukemia were reviewed. Chromosomal analysis was successful in 240 cases. Of these cases, 18 (8%) had abnormalities in 9p and they were compared with patients with normal karyotypes and patients with t(9;22)/BCR-ABL. Patients with abnormalities of chromosome 9 showed significantly shorter overall survival compared with patients with normal karyotypes. In fact, overall survival was similar to that in the poor prognosis t(9;22)/BCR-ABL-positive group. Our data suggest that chromosomal abnormalities involving 9p may have a significant negative impact on survival in adult B-precursor acute lymphoblastic leukemia.
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| 2. |
- Rogström, Lina, et al.
(författare)
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Age hardening in arc-evaporated ZrAlN thin films
- 2010
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Ingår i: Scripta Materialia. - Amsterdam : Elsevier Science B.V.. - 1359-6462 .- 1872-8456. ; 62:10, s. 739-741
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Tidskriftsartikel (refereegranskat)abstract
- Zr0.44Al0.56N1.20 films were deposited by reactive arc evaporation on WC-Co substrates. As-deposited films have a defect-rich NaCl-cubic and wurtzite phase mixture. During annealing at 1100 degrees C the films undergo simultaneous recovery of the ZrN-rich c-ZrAlN nanoscale domains and formation of semicoherent w-ZrAlN nanobricks, while the excess nitrogen is released. This process results in an age hardening effect as high as 36%, as determined by nanoindentation. At 1200 degrees C, the w-AlN recrystallizes and the hardening effect is lost.
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| 3. |
- Rogström, Lina, et al.
(författare)
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Thermal stability and mechanical properties of arc evaporated ZrN/ZrAlN multilayers
- 2010
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Ingår i: Thin Solid Films. - : Elsevier. - 0040-6090 .- 1879-2731. ; 519:2, s. 694-699
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Tidskriftsartikel (refereegranskat)abstract
- ZrN1.20/Zr0.44Al0.56N1.20 multilayer films as well as ZrN1.17 and Zr0.44Al0.56N1.20 films were deposited by reactive arc evaporation on WC–Co substrates. Samples were post-deposition annealed for 2 h at 800–1200 °C. As-deposited and heat treated films were characterized by scanning transmission electron microscopy, X-ray diffraction and nanoindentation. The thermal stability was studied using a combination of differential scanning calorimetry, thermogravimetry, and mass spectrometry. The as-deposited Zr0.44Al0.56N1.20 film exhibits a nanocomposite structure of cubic and wurtzite ZrAlN. During annealing, the formation of ZrN- and AlN-rich domains results in age hardening of both the Zr0.44Al0.56N1.20 and the ZrN/ZrAlN multilayers. The age hardening is enhanced in the ZrN/ZrAlN multilayer due to straining of the ZrAlN sublayers in which a maximum hardness of 31 GPa is obtained after annealing at 1100 °C.
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| 4. |
- Syed, Bilal, 1977-, et al.
(författare)
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Effect of work function and cohesive energy of the constituent phases of Ti-50 at.% Al cathode during arc deposition of Ti-Al-N coatings
- 2019
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Ingår i: Surface & Coatings Technology. - USA : Elsevier. - 0257-8972 .- 1879-3347. ; 357, s. 393-401
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Tidskriftsartikel (refereegranskat)abstract
- The differences in work function (W.F.) and cohesive energy (C.E.) of the phases constituting the cathode, plays an important role in the formation of the converted layer at its near-surface region during cathodic arc deposition. As a consequence, this also affects the deposition conditions for the coatings. In this study, we explore the effect of W.F. and C.E. of the constituent phases during arc evaporation by utilizing two kinds of customized Ti-50 at.% Al cathodes with different phase compositions. Our results show that during reactive arc evaporation the disparity in W.F. and C.E. among the constituent phases of Ti-50 at.% Al cathodes leads to preferential erosion of the phases with lower W.F. and C.E. The aforementioned preferential erosion begets higher surface roughness on the Ti-50 at.% Al cathode with a wider range of W.F. and C.E. disparity. It is also observed that the thermal conductivity of the Ti-50 at.% Al cathode plays a dominant role in the deposition rate of Ti-Al-N coating. This article also presents how the surface geometry of the cathode in the presence of arc guiding magnetic field significantly influences the microstructure of the deposited coatings.
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| 5. |
- Syed, Bilal, et al.
(författare)
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Morphology and microstructure evolution of Ti-50 at.% Al cathodes during cathodic arc deposition of Ti-Al-N coatings
- 2017
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Ingår i: Journal of Applied Physics. - Melville, New York 11747-4300 : American Institute of Physics (AIP). - 0021-8979 .- 1089-7550. ; 121:24
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Tidskriftsartikel (refereegranskat)abstract
- Today's research on the cathodic arc deposition technique and coatings therefrom primarily focuses on the effects of, e.g., nitrogen partial pressure, growth temperature, and substrate bias. Detailed studies on the morphology and structure of the starting material—the cathode—during film growth and its influence on coating properties at different process conditions are rare. This work aims to study the evolution of the converted layer, its morphology, and microstructure, as a function of the cathode material grain size during deposition of Ti-Al-N coatings. The coatings were reactively grown in pure N2discharges from powder metallurgically manufactured Ti-50 at.% Al cathodes with grain size distribution averages close to 1800, 100, 50, and 10 μm, respectively, and characterized with respect to microstructure, composition, and mechanical properties. The results indicate that for the cathode of 1800 μm grain size the disparity in the work function among parent phases plays a dominant role in the pronounced erosion of Al, which yields the coatings rich in macro-particles and of high Al content. We further observed that a reduction in the grain size of Ti-50 at.% Al cathodes to 10 μm provides favorable conditions for self-sustaining reactions between Ti and Al phases upon arcing to form γ phase. The combination of self-sustaining reaction and the arc process not only result in the formation of hole-like and sub-hole features on the converted layer but also generate coatings of high Al content and laden with macro-particles.
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| 6. |
- Abrahamsson, Henrik, et al.
(författare)
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Connected Vehicles in Cellular Networks : Multi-Access Versus Single-Access Performance
- 2018
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Ingår i: TMA 2018 - Proceedings of the 2nd Network Traffic Measurement and Analysis Conference. - : Institute of Electrical and Electronics Engineers Inc.. - 9783903176096
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Konferensbidrag (refereegranskat)abstract
- Connected vehicles can make roads traffic safer and more efficient, but require the mobile networks to handle time-critical applications. Using the MONROE mobile broadband measurement testbed we conduct a multi-access measurement study on buses. The objective is to understand what network performance connected vehicles can expect in today's mobile networks, in terms of transaction times and availability. The goal is also to understand to what extent access to several operators in parallel can improve communication performance. In our measurement experiments we repeatedly transfer warning messages from moving buses to a stationary server. We triplicate the messages and always perform three transactions in parallel over three different cellular operators. This creates a dataset with which we can compare the operators in an objective way and with which we can study the potential for multi-access. In this paper we use the triple-access dataset to evaluate single-access selection strategies, where one operator is chosen for each transaction. We show that if we have access to three operators and for each transaction choose the operator with best access technology and best signal quality then we can significantly improve availability and transaction times compared to the individual operators. The median transaction time improves with 6% compared to the best single operator and with 61% compared to the worst single operator. The 90-percentile transaction time improves with 23% compared to the best single operator and with 65% compared to the worst single operator.
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| 7. |
- Abrahamsson, Henrik
(författare)
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Network overload avoidance by traffic engineering and content caching
- 2012
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Doktorsavhandling (övrigt vetenskapligt/konstnärligt)abstract
- The Internet traffic volume continues to grow at a great rate, now driven by video and TV distribution. For network operators it is important to avoid congestion in the network, and to meet service level agreements with their customers. This thesis presents work on two methods operators can use to reduce links loads in their networks: traffic engineering and content caching.This thesis studies access patterns for TV and video and the potential for caching. The investigation is done both using simulation and by analysis of logs from a large TV-on-Demand system over four months.The results show that there is a small set of programs that account for a large fraction of the requests and that a comparatively small local cache can be used to significantly reduce the peak link loads during prime time. The investigation also demonstrates how the popularity of programs changes over time and shows that the access pattern in a TV-on-Demand system very much depends on the content type.For traffic engineering the objective is to avoid congestion in the network and to make better use of available resources by adapting the routing to the current traffic situation. The main challenge for traffic engineering in IP networks is to cope with the dynamics of Internet traffic demands.This thesis proposes L-balanced routings that route the traffic on the shortest paths possible but make sure that no link is utilised to more than a given level L. L-balanced routing gives efficient routing of traffic and controlled spare capacity to handle unpredictable changes in traffic. We present an L-balanced routing algorithm and a heuristic search method for finding L-balanced weight settings for the legacy routing protocols OSPF and IS-IS. We show that the search and the resulting weight settings work well in real network scenarios.
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| 8. |
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| 9. |
- Ahlgren, Bengt, et al.
(författare)
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Integrated layer processing can be hazardous to your performance
- 1997. - 1
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Konferensbidrag (refereegranskat)abstract
- Integrated Layer Processing (ILP) has been presented as an implementation technique to improve communication protocol performance by reducing the number of memory references. Previous research has however not pointed out that in some circumstances ILP can significantly increase the number of memory references, resulting in lower communication throughput. We explore the performance effects of applying ILP to data manipulation functions with varying characteristics. The functions are generated from a set of parameters including input and output block size, state size and number of instructions. We present experimental data for varying function state sizes, number of integrated functions and instruction counts. The results clearly show that the aggregated state of the functions must fit in registers for ILP to be competitive.
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| 10. |
- Ahlgren, Bengt, et al.
(författare)
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Multimedia transport service and protocol issues
- 1992. - 1
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Rapport (övrigt vetenskapligt/konstnärligt)abstract
- This paper considers the issues of a real time transport service needed by multimedia applications for transferring digital video and audio. Three classes of transport service are defined with different levels of real time constraints. Methods for error control are considered for the classes, and the classes are discussed with respect to the application requirements.
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