SwePub - sökning: WFRF:(Aichholz Charlotte)

Numrering	Referens	Omslagsbild	Hitta
1.	Sauvage, Christopher, et al. (författare) Domestication rewired gene expression and nucleotide diversity patterns in tomato 2017 Ingår i: The Plant Journal. - : WILEY. - 0960-7412 .- 1365-313X. ; 91:4, s. 631-645 Tidskriftsartikel (refereegranskat)abstract Plant domestication has led to considerable phenotypic modifications from wild species to modern varieties. However, although changes in key traits have been well documented, less is known about the underlying molecular mechanisms, such as the reduction of molecular diversity or global gene co-expression patterns. In this study, we used a combination of gene expression and population genetics in wild and crop tomato to decipher the footprints of domestication. We found a set of 1729 differentially expressed genes (DEG) between the two genetic groups, belonging to 17 clusters of co-expressed DEG, suggesting that domestication affected not only individual genes but also regulatory networks. Five co-expression clusters were enriched in functional terms involving carbohydrate metabolism or epigenetic regulation of gene expression. We detected differences in nucleotide diversity between the crop and wild groups specific to DEG. Our study provides an extensive profiling of the rewiring of gene co-expression induced by the domestication syndrome in one of the main crop species.

Sauvage, Christopher, et al. (författare)
Domestication rewired gene expression and nucleotide diversity patterns in tomato
2017
Ingår i: The Plant Journal. - : WILEY. - 0960-7412 .- 1365-313X. ; 91:4, s. 631-645
Tidskriftsartikel (refereegranskat)abstract
- Plant domestication has led to considerable phenotypic modifications from wild species to modern varieties. However, although changes in key traits have been well documented, less is known about the underlying molecular mechanisms, such as the reduction of molecular diversity or global gene co-expression patterns. In this study, we used a combination of gene expression and population genetics in wild and crop tomato to decipher the footprints of domestication. We found a set of 1729 differentially expressed genes (DEG) between the two genetic groups, belonging to 17 clusters of co-expressed DEG, suggesting that domestication affected not only individual genes but also regulatory networks. Five co-expression clusters were enriched in functional terms involving carbohydrate metabolism or epigenetic regulation of gene expression. We detected differences in nucleotide diversity between the crop and wild groups specific to DEG. Our study provides an extensive profiling of the rewiring of gene co-expression induced by the domestication syndrome in one of the main crop species.

Träfflista för sökning "WFRF:(Aichholz Charlotte) "