| 1. |
- Tabiri, S, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 2. |
- Bravo, L, et al.
(författare)
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- 2021
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swepub:Mat__t
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| 3. |
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| 4. |
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| 5. |
- Alqahtani, F. Y., et al.
(författare)
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Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus : a retrospective study
- 2019
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Ingår i: Epidemiology and Infection. - : Cambridge University Press. - 0950-2688 .- 1469-4409. ; 147
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Tidskriftsartikel (refereegranskat)abstract
- The Middle East respiratory syndrome coronavirus (MERS-CoV) is a life-threatening respiratory disease with a high case fatality rate; however, its risk factors remain unclear. We aimed to explore the influence of demographic factors, clinical manifestations and underlying comorbidities on mortality in MERS-CoV patients. Retrospective chart reviews were performed to identify all laboratory-confirmed cases of MERS-COV infection in Saudi Arabia that were reported to the Ministry of Health of Saudi Arabia between 23 April 2014 and 7 June 2016. Statistical analyses were conducted to assess the effect of sex, age, clinical presentation and comorbidities on mortality from MERS-CoV. A total of 281 confirmed MERS-CoV cases were identified: 167 (59.4%) patients were male and 55 (20%) died. Mortality predominantly occurred among Saudi nationals and older patients and was significantly associated with respiratory failure and shortness of breath. Of the 281 confirmed cases, 160 (56.9%) involved comorbidities, wherein diabetes mellitus, hypertension, ischemic heart disease, congestive heart failure, end-stage renal disease and chronic kidney disease were significantly associated with mortality from MERS-CoV and two or three comorbidities significantly affected the fatality rates from MERS-CoV. The findings of this study show that old age and the existence of underlying comorbidities significantly increase mortality from MERS-CoV.
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| 6. |
- El-Kemary, Maged, et al.
(författare)
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Calendula officinalis-mediated biosynthesis of Silver Nanoparticles and their Electrochemical and Optical Characterization
- 2016
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Ingår i: International Journal of Electrochemical Science. - : Elsevier BV. - 1452-3981. ; 11:12, s. 10795-10805
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Tidskriftsartikel (refereegranskat)abstract
- The metal nanoparticles synthesis is highly explored field of nanotechnology. The biological methods seem to be more effective. A simple and elegant method is adopted to prepare Silver nanoparticles (AgNPs) in a single step using Calendula officinalis extract (COE) as reducing and stabilizing agent. The plant extract is mixed with AgNO3 to get biosynthesized AgNPs. The biosynthesized AgNPs were both optically and electrochemically characterized by UV-Vis, Infrared spectroscopy, Transmission Electron Microscopy, Fluorescence spectroscopy, Zeta potential and Cyclic Voltammetry. The results showed Calendula officinalis extract is a useful bioreductant for the synthesis of AgNPs. This study infers that the size of biosynthesized AgNPs ranges from 30 to 50 nm. The surface plasmon resonance peak in the UV-Vis absorption spectra shows maximum absorption at 435 nm. Fluorescence spectra of silver nanoparticles, which show an emission peak at 468 nm have also been studied. Zeta potential analysis ensured the biosynthesized AgNPs are highly stable. Using this environmentally friendly method of biological AgNPs production supplies rates of biosynthesis facile in comparison with other chemical and engineered routes. The employment of traditional medicine in biosynthesis protocols can potentially open new doors in various human health and well-being implications such as cosmetics, foods and medicine.
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