| 1. |
- Ferrando, Carlos, et al.
(författare)
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Effects of oxygen on post-surgical infections during an individualised perioperative open-lung ventilatory strategy : a randomised controlled trial
- 2020
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Ingår i: British Journal of Anaesthesia. - : ELSEVIER SCI LTD. - 0007-0912 .- 1471-6771. ; 124:1, s. 110-120
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Tidskriftsartikel (refereegranskat)abstract
- Background: We aimed to examine whether using a high fraction of inspired oxygen (FIO2) in the context of an individualised intra- and postoperative open-lung ventilation approach could decrease surgical site infection (SSI) in patients scheduled for abdominal surgery. Methods: We performed a multicentre, randomised controlled clinical trial in a network of 21 university hospitals from June 6, 2017 to July 19, 2018. Patients undergoing abdominal surgery were randomly assigned to receive a high (0.80) or conventional (0.3) FIO2 during the intraoperative period and during the first 3 postoperative hours. All patients were mechanically ventilated with an open-lung strategy, which included recruitment manoeuvres and individualised positive end-expiratory pressure for the best respiratory-system compliance, and individualised continuous postoperative airway pressure for adequate peripheral oxyhaemoglobin saturation. The primary outcome was the prevalence of SSI within the first 7 postoperative days. The secondary outcomes were composites of systemic complications, length of intensive care and hospital stay, and 6-month mortality. Results: We enrolled 740 subjects: 371 in the high FIO2 group and 369 in the low FIO2 group. Data from 717 subjects were available for final analysis. The rate of SSI during the first postoperative week did not differ between high (8.9%) and low (9.4%) FIO2 groups (relative risk [RR]: 0.94; 95% confidence interval [CI]: 0.59-1.50; P=0.90]). Secondary outcomes, such as atelectasis (7.7% vs 9.8%; RR: 0.77; 95% CI: 0.48-1.25; P=0.38) and myocardial ischaemia (0.6% [n=2] vs 0% [n=0]; P=0.47) did not differ between groups. Conclusions: An oxygenation strategy using high FIO2 compared with conventional FIO2 did not reduce postoperative SSIs in abdominal surgery. No differences in secondary outcomes or adverse events were found.
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| 2. |
- Valdiosera, Cristina, et al.
(författare)
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Four millennia of Iberian biomolecular prehistory illustrate the impact of prehistoric migrations at the far end of Eurasia
- 2018
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Ingår i: Proceedings of the National Academy of Sciences of the United States of America. - : Proceedings of the National Academy of Sciences. - 0027-8424 .- 1091-6490. ; 115:13, s. 3428-3433
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Tidskriftsartikel (refereegranskat)abstract
- Population genomic studies of ancient human remains have shown how modern-day European population structure has been shaped by a number of prehistoric migrations. The Neolithization of Europe has been associated with large-scale migrations from Anatolia, which was followed by migrations of herders from the Pontic steppe at the onset of the Bronze Age. Southwestern Europe was one of the last parts of the continent reached by these migrations, and modern-day populations from this region show intriguing similarities to the initial Neolithic migrants. Partly due to climatic conditions that are unfavorable for DNA preservation, regional studies on the Mediterranean remain challenging. Here, we present genome-wide sequence data from 13 individuals combined with stable isotope analysis from the north and south of Iberia covering a four-millennial temporal transect (7,500-3,500 BP). Early Iberian farmers and Early Central European farmers exhibit significant genetic differences, suggesting two independent fronts of the Neolithic expansion. The first Neolithic migrants that arrived in Iberia had low levels of genetic diversity, potentially reflecting a small number of individuals; this diversity gradually increased over time from mixing with local hunter-gatherers and potential population expansion. The impact of post-Neolithic migrations on Iberia was much smaller than for the rest of the continent, showing little external influence from the Neolithic to the Bronze Age. Paleodietary reconstruction shows that these populations have a remarkable degree of dietary homogeneity across space and time, suggesting a strong reliance on terrestrial food resources despite changing culture and genetic make-up.
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| 3. |
- Vandaele, Ann Carine, et al.
(författare)
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Martian dust storm impact on atmospheric H2O and D/H observed by ExoMars Trace Gas Orbiter
- 2019
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Ingår i: Nature. - : Springer. - 1476-4687 .- 1476-4687 .- 0028-0836. ; 568:7753, s. 521-525
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Tidskriftsartikel (övrigt vetenskapligt/konstnärligt)abstract
- Global dust storms on Mars are rare1,2 but can affect the Martian atmosphere for several months. They can cause changes in atmospheric dynamics and inflation of the atmosphere3, primarily owing to solar heating of the dust3. In turn, changes in atmospheric dynamics can affect the distribution of atmospheric water vapour, with potential implications for the atmospheric photochemistry and climate on Mars4. Recent observations of the water vapour abundance in the Martian atmosphere during dust storm conditions revealed a high-altitude increase in atmospheric water vapour that was more pronounced at high northern latitudes5,6, as well as a decrease in the water column at low latitudes7,8. Here we present concurrent, high-resolution measurements of dust, water and semiheavy water (HDO) at the onset of a global dust storm, obtained by the NOMAD and ACS instruments onboard the ExoMars Trace Gas Orbiter. We report the vertical distribution of the HDO/H2O ratio (D/H) from the planetary boundary layer up to an altitude of 80 kilometres. Our findings suggest that before the onset of the dust storm, HDO abundances were reduced to levels below detectability at altitudes above 40 kilometres. This decrease in HDO coincided with the presence of water-ice clouds. During the storm, an increase in the abundance of H2O and HDO was observed at altitudes between 40 and 80 kilometres. We propose that these increased abundances may be the result of warmer temperatures during the dust storm causing stronger atmospheric circulation and preventing ice cloud formation, which may confine water vapour to lower altitudes through gravitational fall and subsequent sublimation of ice crystals3. The observed changes in H2O and HDO abundance occurred within a few days during the development of the dust storm, suggesting a fast impact of dust storms on the Martian atmosphere.
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| 4. |
- Alday, Juan, et al.
(författare)
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New constraints on Ganymede's hydrogen corona : Analysis of Lyman-alpha emissions observed by HST/STIS between 1998 and 2014
- 2017
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Ingår i: Planetary and Space Science. - : Elsevier. - 0032-0633 .- 1873-5088. ; 148, s. 35-44
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Tidskriftsartikel (refereegranskat)abstract
- Far-ultraviolet observations of Ganymede's atmospheric emissions were obtained with the Space Telescope Imaging Spectrograph (STIS) onboard of the Hubble Space Telescope (HST) on several occasions between 1998 and 2014. We analyze the Lyman-alpha emission from four HST campaigns in order to constrain the abundance and variation of atomic hydrogen in Ganymede's atmosphere. We apply a forward model that estimates surface reflection and resonant scattering in an escaping corona of the solar Lyman-alpha flux, taking into account the effects of the hydrogen in the interplanetary medium. The atmospheric emissions around Ganymede's disk derived for the observations taken between 1998 and 2011 are consistent with a hydrogen corona in the density range of (5-8) x 10(3) cm(-3) at the surface. The hydrogen density appears to be generally stable in that period. In 2014, Ganymede's corona brightness is approximately 3 times lower during two observations of Ganymede's trailing hemisphere and hardly detectable at all during two observations of the leading hemisphere. We also investigate extinction of Ganymede's coronal emissions in the Earth's upper atmosphere or geocorona. For small Doppler shifts, resonant scattering in the geocorona of the moon corona emissions can effectively reduce the brightness observed by HST. In the case of the 2014 leading hemisphere observations, an estimated extinction of 80% might explain the non-detection of Ganymede's hydrogen corona. Geocoronal extinction might also explain a previously detected hemispheric difference from Callisto's hydrogen corona.
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| 5. |
- Becker, Tracy M., et al.
(författare)
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Mid-ultraviolet Hubble Observations of Europa and the Global Surface Distribution of SO2
- 2022
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Ingår i: The Planetary Science Journal. - : IOP Publishing Ltd. - 2632-3338. ; 3:6
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Tidskriftsartikel (refereegranskat)abstract
- We present spatially resolved reflectance spectra of Europa's surface in the wavelength range of 210-315 nm obtained by the Hubble Space Telescope Imaging Spectrograph in 2018 and 2019. These data provide the first high-quality, near-global spectral observations of Europa from 210 to 240 nm. They show that the reflectance of Europa's leading, trailing, anti-Jovian, and sub-Jovian hemispheres is similar to 5% near 210 nm, with varying spectral slopes across the mid-UV. This low albedo, even on the more "pristine" leading hemisphere, indicates a lack of the signature far-UV spectral edge characteristic of water ice. We detected and mapped a strong absorption feature at 280 nm that is consistent with an S-O bond that has previously been attributed to SO2 on the surface, hypothesized to be formed through radiolytic processing of Iogenic sulfur ions that have been preferentially emplaced on Europa's trailing hemisphere by Jupiter's magnetic field. Our models show that small inclusions of SO2 (0.1%) within the water ice are sufficient to produce the 280 nm feature without producing a feature at 4.07 mu m, which has not been observed in ground-based spectral observations of Europa. This data set is the first to produce a spatially resolved, near-global map of the assumed SO2 feature, which is primarily concentrated near the apex of the trailing hemisphere and correlated with large-scale darker regions in both the visible and the ultraviolet. This distribution is consistent with "cold" exogenic sulfur ion bombardment on Europa.
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| 6. |
- Hagenbo, Andreas, 1987-, et al.
(författare)
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Production and turnover of mycorrhizal soil mycelium relate to variation in drought conditions in Mediterranean Pinus pinaster, Pinus sylvestris and Quercus ilex forests
- 2021
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Ingår i: New Phytologist. - : Wiley-Blackwell Publishing Inc.. - 0028-646X .- 1469-8137. ; 230:4, s. 1609-1622
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Tidskriftsartikel (refereegranskat)abstract
- In forests, ectomycorrhizal mycelium is pivotal for driving soil carbon and nutrient cycles, but how ectomycorrhizal mycelial dynamics vary in ecosystems with drought periods is unknown. We quantified production and turnover of mycorrhizal mycelium in Mediterranean Pinus pinaster, Pinus sylvestris and Quercus ilex forests and related the estimates to standardized precipitation index (SPI), to study how mycelial dynamics relates to tree species and drought-moisture conditions.Production and turnover of mycelium was estimated between July-February, by quantifying the fungal biomass (ergosterol) in ingrowth mesh bags and using statistical modelling. SPI for time scales of 1 to 3 months, was calculated from precipitation records and precipitation data over the study period.Forests dominated by Pinus trees displayed higher biomass but were seasonally more variable, as opposed to Q. ilex forests where the mycelial biomass remained lower and stable over the season. Production and turnover respectively varied between 1.4-5.9 kg ha-1 day-1 and 7.2-9.9 times year-1 over the different forest types and were positively correlated with 2- and 3-month SPI over the study period.Our results demonstrate that mycorrhizal mycelial biomass vary with season and tree species and we speculate that production and turnover are related to physiology and plant-host performance during drought.
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| 7. |
- Mogan, Shane R. Carberry R., et al.
(författare)
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Callisto's Atmosphere : First Evidence for H-2 and Constraints on H2O
- 2022
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Ingår i: Journal of Geophysical Research - Planets. - : American Geophysical Union (AGU). - 2169-9097 .- 2169-9100. ; 127:11
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Tidskriftsartikel (refereegranskat)abstract
- We explore the parameter space for the contribution to Callisto's H corona observed by the Hubble Space Telescope from sublimated H2O and radiolytically produced H-2 using the Direct Simulation Monte Carlo method. The spatial morphology of this corona produced via photoelectron and magnetospheric electron-impact-induced dissociation is described by tracking the motion of and simulating collisions between the hot H atoms and thermal molecules including a near-surface O-2 component. Our results indicate that sublimated H2O produced from the surface ice, whether assumed to be intimately mixed with or distinctly segregated from the dark nonice or ice-poor regolith, cannot explain the observed structure of the H corona. On the other hand, a global H-2 component can reproduce the observation, and is also capable of producing the enhanced electron densities observed at high altitudes by Galileo's plasma-wave instrument, providing the first evidence of H-2 in Callisto's atmosphere. The range of H-2 surface densities explored, under a variety of conditions, that are consistent with these observations is similar to(0.4-1) x 10(8) cm(-3). The simulated H-2 escape rates and estimated lifetimes suggest that Callisto has a neutral H-2 torus. We also place a rough upper limit on the peak H2O number density (less than or similar to 10(8) cm(-3)), column density (less than or similar to 10(15) cm(-2)), and sublimation flux (less than or similar to 10(12) cm(-2) s(-1)), all of which are 1-2 orders of magnitude less than that assumed in previous models. Finally, we discuss the implications of these results, as well as how they compare to Europa and Ganymede.
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| 8. |
- Roth, Lorenz, et al.
(författare)
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Detection of a hydrogen corona at Callisto
- 2017
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Ingår i: Journal of Geophysical Research - Planets. - : Blackwell Publishing. - 2169-9097 .- 2169-9100. ; 122:5, s. 1046-1055
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Tidskriftsartikel (refereegranskat)abstract
- In December 2001, the Space Telescope Imaging Spectrograph of the Hubble Space Telescope obtained far-ultraviolet spectral images of Jupiter's moon Callisto. The leading and trailing hemispheres were observed in the spectral range 1190 Å to 1720 Å when the moon was at eastern and western elongations, respectively. We analyzed the hydrogen Lyman α (1216 Å) signal in the two observations and found that faint atmospheric emissions extending up to several moon radii away are present in addition to the solar flux reflected off the surface. We show that the detected atmospheric Lyman α emissions are consistent with an escaping hydrogen corona with a vertical column density in the range of (6–12) ×1011 cm−2. The derived hydrogen abundance is about 2 times higher when the moon is at eastern elongation, possibly related to increased water sublimation when the visibly darker leading hemisphere is illuminated by the Sun. The detected hemispheric difference is larger than the measurement uncertainties providing first evidence for variations in Callisto's neutral atmosphere.
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| 9. |
- Trumbo, Samantha K., et al.
(författare)
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A New UV Spectral Feature on Europa : Confirmation of NaCl in Leading-hemisphere Chaos Terrain
- 2022
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Ingår i: The Planetary Science Journal. - : American Astronomical Society. - 2632-3338. ; 3:2
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Tidskriftsartikel (refereegranskat)abstract
- Recent visible-wavelength observations of Europa's surface obtained with the Hubble Space Telescope (HST) revealed the presence of an absorption feature near 450 nm that appears spatially correlated with leading-hemisphere chaos terrain. This feature was interpreted to reflect the presence of irradiated sodium chloride ultimately sourced from the interior. Here, we use ultraviolet spectra also collected with the HST to detect an additional previously unseen absorption near 230 nm, which spatially correlates with the 450 nm feature and with the same leading-hemisphere chaos terrain. We find that the new ultraviolet feature is also well matched by irradiated sodium chloride at Europa-like conditions. Such confirmation of sodium chloride within geologically young regions has important implications for Europa's subsurface composition.
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